Mechanoneural Interfaces (MIs) and methods of forming MIs are provided, including cutaneous mechanoneural interfaces (CMIs) and proprioceptive mechanoneural interfaces (PMIs). A CMI includes a device in operative arrangement with a muscle actuator to stimulate muscle contraction, the muscle actuator disposed in a substantially circumferential configuration about a skin flap that includes a native or regenerative neurovascular structure of an amputated body segment. A PMI includes an actuator mechanically linked to a muscle end organ and configured to apply a force to the muscle end organ, the actuator including a synthetic actuator or a biological muscle actuator. The muscle end organ is of an agonist-antagonist muscle pair and can include at least one of a native or regenerative neurovascular structure. CMIs and PMIs can each further include a controller configured to provide a stimulation signal or operate an actuator based on a signal received from a sensor of a prosthetic device.

The present invention relates to a system for neuromuscular rehabilitation of a patient having an affected limb comprising: a feedback member arranged to give real-time visual feedback; a plurality of electrodes arranged to acquire an electric signal corresponding to an intent to move said affected limb; a control unit configured to: perform pattern recognition of said electric signals, wherein at least one feature in said electric signal is used to predict motion intent of said affected limb adjacent to at least one joint, such aggregated motions of said affected limb are predicted; based on output signals from said performed pattern recognition, control said feedback member to perform actions corresponding to said motions, whereby said actions of said feedback member are individually and simultaneously controlled by said patient via said intended motions.

A prosthetic arm apparatus comprising a plurality of segments that provide a user of the prosthetic arm apparatus with substantially the same movement capability and function as a human arm. The segments are connectable to one another and connectable to a harness mount that may be adorned by the user. Each segment of the plurality of segments provides a portion of the movement capability, enabling the plurality of connected segments connected to the harness mount to provide substantially the same movement capability as that lacking in the user.

An orthosis or prosthesis system comprising at least one orthosis or prosthesis, at least one pair of electrodes for contacting the body of the user of the orthosis or prosthesis in order to capture muscle-related signals, at least one evaluation unit for muscle-related signals captured by the at least one electrode pair, at least one actuator for moving the at least one orthosis or prosthesis, and at least one control unit for controlling the at least one actuator. The at least one electrode pair is designed to capture at least a first muscle-related signal using a first measurement frequency and a second muscle-related signal using a second measurement frequency. The at least one evaluation unit evaluates a phase of the first signal and a phase of the second signal. The muscle-related signals can be bioimpedance signals. The system makes it possible to distinguish between muscle contractions and interfering signals.

Proprioceptive feedback is provided in a residual limb of a person that includes forming a linkage between a pair of agonist and antagonist muscles, forming a sliding surface over which the agonist and antagonist muscles slide. The sliding surface can include a synovial sleeve, a bridge formed between the distal ends of bones, or a fixture that is osseointegrated into the bone. The invention also includes a system for transdermal electrical communication in a person that includes a percutaneous access device, a sensory device that communicates signals between a muscle and the percutaneous device, and a stimulation device in communication with the percutaneous access device. In another embodiment, a closed-loop functional stimulation system restores lost functionality to a person that suffers from impairment of a neurological control system or at least partial loss of a limb.

Methods and systems to interface between physiological devices and a prosthetic device, including to receive a plurality of types of physiological activity signals from a user, decode a user movement intent from each of the plurality of signals types, and fuse the movement intents into a joint decision to control moveable elements of the prosthetic device.

A prosthetic arm apparatus comprising a plurality of segments that provide a user of the prosthetic arm apparatus with substantially the same movement capability and function as a human arm. The segments are connectable to one another and connectable to a harness mount that may be adorned by the user. Each segment of the plurality of segments provides a portion of the movement capability, enabling the plurality of connected segments connected to the harness mount to provide substantially the same movement capability as that lacking in the user.

Proprioceptive feedback is provided in a residual limb of a person that includes forming a linkage between a pair of agonist and antagonist muscles, forming a sliding surface over which the agonist and antagonist muscles slide. The sliding surface can include a synovial sleeve, a bridge formed between the distal ends of bones, or a fixture that is osseointegrated into the bone. The invention also includes a system for transdermal electrical communication in a person that includes a percutaneous access device, a sensory device that communicates signals between a muscle and the percutaneous device, and a stimulation device in communication with the percutaneous access device. In another embodiment, a closed-loop functional stimulation system restores lost functionality to a person that suffers from impairment of a neurological control system or at least partial loss of a limb.

An orthosis or prosthesis system comprising at least one orthosis or prosthesis, at least one pair of electrodes for contacting the body of the user of the orthosis or prosthesis in order to capture muscle-related signals, at least one evaluation unit for muscle-related signals captured by the at least one electrode pair, at least one actuator for moving the at least one orthosis or prosthesis, and at least one control unit for controlling the at least one actuator. The at least one electrode pair is designed to capture at least a first muscle-related signal using a first measurement frequency and a second muscle-related signal using a second measurement frequency. The at least one evaluation unit evaluates a phase of the first signal and a phase of the second signal. The muscle-relates signals can be bioimpedance signals. The system makes it possible to distinguish between muscle contractions and interfering signals.

Methods and systems to interface between physiological devices and a prosthetic device, including to receive a plurality of types of physiological activity signals from a user, decode a user movement intent from each of the plurality of signals types, and fuse the movement intents into a joint decision to control moveable elements of the prosthetic device.