A method of making a delivery system for a prosthesis includes providing a catheter shaft, sliding a plurality of rings over the catheter shaft, each of the rings having an inner diameter larger than an outer diameter of the catheter shaft, fixing a pull wire to each of the plurality of rings at a common circumferential location of the catheter shaft, and coupling a sheath to the pull wire, the sheath positioned over the prosthesis at a distal end of the catheter shaft. Fixing the pull wire to each of the plurality of rings can include wrapping a heat shrink film around each of the plurality of rings and the pull wire, and heating the heat shrink material.

The disclosure relates to a medical kit for the treatment of vascular malformations, in particular aneurysms and/or fistulas, having a permanently implantable covering device, in particular a stent, for covering the vascular malformation, the covering device having a tubular, self-expandable lattice structure and a covering made of an electrospun fabric, the covering being connected to the lattice structure and overlapping the lattice structure at least in part such that, when implanted, the covering is placed over the vascular malformation; and an embolisation means, which can be applied by a feed means in the implanted state for treatment of the vascular malformation, the covering forming a porous membrane which can be penetrated by the feed means for application of the embolisation means and which is designed to lie against the outer periphery of the feed means in the penetrated state.

A medical device delivery system includes a joining element with a bumper having a distal end portion configured to engage a proximal portion of a medical device and a proximal end portion adjacent a distal end portion of an elongated tubular member. The proximal end portion defines a slot having a length along a first direction. The joining element further includes an aperture extending through the bumper and having a first, greater, cross-sectional dimension along a second direction and a second, smaller, cross-sectional dimension along a third direction. The system can include an elongated shaft having a distal region and a flattened region proximal of the distal region, the flattened region having a greatest cross-sectional dimension that is smaller than the first cross-sectional dimension but larger than the second cross-sectional dimension The flattened region can be received within the slot.

A biodegradable flow diverting device (BFDD) that will regulate blood flow into an aneurysmal sac, act as a scaffold for endothelization at the neck of an aneurysm, and degrade after successful dissolution of aneurysm and remodeling of blood vessel. This BFDD and associated fabrication method have the following features: (1) This is a non-braided FDD. The pore shapes, sizes, architectures (especially at the inlet and outlet of the pores), pore densities and porosities can be controlled for the optimum performance depending on the blood vessel and aneurysmal morphologies from patient MRI images, (2) BFDD is developed on a rotary arm with programmable variable speed and diameter in conjunction with a micromotion stage (3) Fabrication system can take any material including blended/composite biomaterials by adjusting temperature of the electro-melt extruder/needle and (4) Fabrication system is compatible with CAM (computer aided manufacturing) software and able to operate based on the adapted G-code.

In one embodiment according to the present invention, a stent is described having a generally cylindrical body formed from a single woven nitinol wire. The distal and proximal ends of the stent include a plurality of loops, some of which include marker members used for visualizing the position of the stent. In another embodiment, the previously described stent includes an inner flow diverting layer.

The invention relates to an insertion system for an implant (1) for influencing the blood flow in the region of aneurysms (22) located at vascular bifurcations. The implant (1) has two distal tubular implant portions (2) which are intended to be placed in blood vessels (21) branching off from the stem blood vessel (20) and which are connected to one another at a branching point (4). The insertion system has two sleeves (5) which are each designed to hold a distal tubular implant portion (2). The two sleeves (5) each have a distal sleeve portion (6) and the distal sleeve portions (6) each have an opening zone (7) extending in the longitudinal direction. The distal sleeve portions (6) are each adjoined proximally by a proximal portion (8), by means of which the sleeves (5) can be retracted in the proximal direction so that the opening zones (7) open and the distal tubular implant portions (2) each pass through the opening zones (7) and are released into the branching blood vessels (21). Alternatively, it is also possible to use an individual sleeve which has an opening zone for gradual release of the implant (1) or an insertion system with the implant (1) releasably attached to the outside.

A method of reducing blood flow within an aneurysm includes: injecting a contrast agent into a blood vessel including an aneurysm; expanding a stent, from a delivery device, across the aneurysm; and confirming that a stagnated area forms in the aneurysm. The stagnated area can form a crescent shape, a mushroom shape, a hemispherical shape, and/or a flat side. Upon confirming that the stagnated area forms in the aneurysm, the delivery device can be withdrawn from the blood vessel. The stagnated area can include the contrast agent. If the stagnated area does not form in the aneurysm, a second occluding device may be deployed. After withdrawing the delivery device, substantially all of the aneurysm progressively thromboses.

In one embodiment according to the present invention, a stent is described having a generally cylindrical body formed from a single woven nitinol wire. The distal and proximal ends of the stent include a plurality of loops, some of which include marker members used for visualizing the position of the stent. In another embodiment, the previously described stent includes an inner flow diverting layer.

A stent assembly system and a stent assembly method are provided. The stent assembly system includes a stent and an assembly instrument; the assembly instrument is configured to assemble and deliver the stent, and includes a sheath core tube, an outer sheath tube, and an assembly part; the outer sheath tube slidably surrounds the sheath core tube in an axial direction; an accommodating cavity for accommodating the stent is formed between the inner wall of the outer sheath tube and the outer wall of the sheath core tube; the assembly part has a fixed end and a free end opposite to the fixed end, and the fixed end is connected to the sheath core tube; and when the stent is crimped radially on the sheath core tube, the free end is hooked to the stent to limit the stent.

A stent with varying porosity is described. The stent can be comprised of multiple stents attached together. A braided stent may have selected regions of increased thickness. The stent may be comprised of wires that are welded together at their ends in order to minimize vessel trauma. The stent may comprise a helically wound radiopaque wire wound through the stent.