A medical device and method used for patient temperature management, wherein the device is designed to cool the surface of the patient's head and blood flow to the head and neck of a patient after trauma in order to prevent inflammation and reduce swelling in the brain, is portable with a rapid cooling capability feature, does not require an ICU setting, eliminates certain complications that could affect the patient otherwise, and can be easily placed on the patient with little training or expertise.

Thermal management devices and associated systems and methods are disclosed herein. In some embodiments, a representative device can comprise (i) thermoelectric components (TECs) each including a first side configured to be operated at a desired temperature and a second side opposite the first side, and (ii) a heat transfer system including an array of fluid distribution networks, an inlet passage coupled to the fluid distribution networks, and an outlet passage coupled to the fluid distribution networks. In operation, a working fluid flows through the fluid distribution networks from the inlet passage to the outlet passage, and absorbs heat from the fluid distribution networks. The inlet and outlet passages can be fluidically coupled to individual fluid distribution networks such that pressure drop and/or temperature drop of the working fluid across the individual fluid distribution networks is about the same as one another.

A warming device may include a batting layer having a phase change material. The batting layer may have a patient side and an upper side. A hot melt fabric adhesive may be applied to the patient side and upper side of the batting. A first fabric layer may be adhered to the hot melt fabric on the patient side of the batting. The first fabric layer may have a phase change material integrated coating. An insulation layer may be adhered to the hot melt fabric on the upper side of the batting. A second fabric layer may be coupled to the insulation layer.

A brassiere incorporating a hot flash mitigation system for cooling the upper torso, chest and neck area of a wearer is disclosed. The brassiere comprises two front panel sections connectively engaged to each other, at least one rear panel section connectively engaged to each of the two front panel sections. The hot flash mitigation system provides a deformable reservoir for containing and dispensing a fluid therefrom. The deformable reservoir is disposed in mating and contacting engagement with the brassiere and has an outlet in cooperative fluid engagement thereto. At least one duct disposed proximate to one of the at least two front panel sections is in fluid engagement with the outlet of the deformable reservoir. At least one nozzle disposed upon an end of the duct distal from the deformable reservoir operatively conveys the fluid from the duct to the upper torso, chest and neck area of the wearer.

Wearable heat transfer devices and associated systems and methods are disclosed herein. In some embodiments, a representative heat transfer device can comprise (i) thermoelectric components each having a first side and a second side, (ii) a heat transfer system having a heat exchanger and an array of fluid distribution networks, in which individual fluid distribution networks are thermally coupled to the second side of a corresponding one of the thermoelectric components and fluidically coupled to the heat exchanger, and (iii) a flexible support unit coupled to the first sides of the thermoelectric components and extending at least between individual thermoelectric components, wherein the flexible support unit is a heat spreader configured to enhance heat transfer from a target area.

A cerebral protection system generally includes an array of cold packs, an insulating cover, and optionally a set of trays. The cold pack contains two reactive materials separated by a rupturable membrane. When the first reactive material and the second reactive material are mixed, an endothermic reaction occurs. The system can be used to induce hypothermia in selected regions of the brain when used. The system can be used to treat conditions including concussion, traumatic brain injury (TBI), heatstroke, cardiac arrest, respiratory arrest, anoxic brain injury, ischemic stroke, transient ischemic attack (TIA), or hypoxic ischemic encephalopathy.

Described are methods for inducing browning of adipose tissue. More specifically, the present disclosure relates generally to methods for inducing browning of adipose tissue remote to the treatment location. The methods can include at least a first treatment and a second treatment, wherein the treatments comprise applying a cooling element to a local adipose tissue deposit, wherein the cooling element cools the local adipose tissue deposit to a temperature of between 0° C. to 30° C. for a period of time sufficient to induce browning of adipose tissue in one or more areas of the subject's body remote to the local adipose tissue deposit.

A cervical collar that facilitates therapeutic hypothermia is provided and includes a cooling device having a front portion and a back portion fixedly coupled to the front portion on one side and removably coupled to the front portion on an opposite side. A fastening device removably couples the back portion to the front portion on the opposite side. The cooling device induces hypothermia in at least a portion of a patient. A sensor is provided that measures a physical characteristic of the patient.

Wearable heat transfer devices and associated systems and methods are disclosed herein. In some embodiments, a representative heat transfer device can comprise (i) thermoelectric components each having a first side and a second side, (ii) a heat transfer system having a heat exchanger and an array of fluid distribution networks, in which individual fluid distribution networks are thermally coupled to the second side of a corresponding one of the thermoelectric components and fluidically coupled to the heat exchanger, and (iii) a flexible support unit coupled to the first sides of the thermoelectric components and extending at least between individual thermoelectric components, wherein the flexible support unit is a heat spreader configured to enhance heat transfer from a target area.

A cervical collar that facilitates therapeutic hypothermia is provided and includes a cooling device having a front portion and a back portion fixedly coupled to the front portion on one side and removably coupled to the front portion on an opposite side. A fastening device removably couples the back portion to the front portion on the opposite side. The cooling device induces hypothermia in at least a portion of a patient. A sensor is provided that measures a physical characteristic of the patient.