Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.

An apparatus and method for providing heat exchange in the lungs of the mammal during partial liquid ventilation are provided. The apparatus and method can control delivery and removal of partial liquid ventilation to the lungs of a mammal by responding to pressure change in the lungs to minimize danger of causing barotrauma to the patient.

The present invention relates to a unique therapeutic garment that wraps around the torso of a patient with a chest related ailment or recovering from a chest related procedure such as, without limitation, a mastectomy, lumpectomy, or the like. The therapeutic garment comprises a web, band or tube-like post-surgical wrap having two opposite ends along the length of the garment, which are secured together over the torso of the user. The therapeutic garment further comprises two pockets that are attached to, or integrally formed with, the wrap garment, such that one pocket covers the left breast of the wearer and the other pocket covers the right breast. Each of the pockets has an opening therein for receipt of a hot pack, cold pack and/or therapeutic device to combat swelling, pain and the like.

A heating patch assembly adapted for use on a human. The preferred heating patch assembly includes a heating patch assembly lining and a heating patch assembly thermal conductor. The preferred heating patch assembly thermal conductor is disposed within the heating patch assembly lining. The preferred heating patch assembly is adapted to induce vasodilation and increase cardiac output in the human. A method for increasing cardiac output including applying the heating patch assembly to a human chest.

A device applies therapeutic treatment to a subject. The therapeutic treatment includes any two modalities applied simultaneously, the modalities selected from compression, heat, vibration, and massage. The device includes a main body; hinges coupled to the main body on each side of the main body; and respective plates connected to the hinges, wherein the respective plates contact opposing surfaces of a body.

The present application relates to a heatable system suitable for use in a patient contacting plate used in medical imaging. The system comprises a heatable laminated structure with a plurality of layers each of which is transparent to imaging radiation and allows for thermal transfer. A heater layer, located between two of the plurality of layers, comprises an electrically resistive material and is transparent to imaging radiation. The laminated structure further includes a conductive path suitable for use in coupling a voltage source to the electrically resistive material in the heatable laminated structure, whereby the laminated structure is heated when current is passing through the conductive path. Also disclosed is a compression plate system and an imaging medical device comprising the heatable system. Methods of making the heatable system and of using it in medical imaging are also disclosed.

Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.

A device comprising a heat-generating component that comprises an alkali metal is provided. The alkali metal in the presence of water at a point of contact of the device undergoes an exothermic reaction to generate heat in situ. The amount of heat generated is proportional to and/or limited by the amount (or moles) of water at the point of contact, and the heat generated is sufficient to achieve an increase in temperature at the point of contact to achieve a therapeutic or beneficial result. In one embodiment, the device is used for reducing sweat production in a subject suffering from excessive sweating or hyperhidrosis. In other embodiments, the device is used to substantially sterilize a surface or render a surface substantially aseptic.

A device comprising a heat-generating component that comprises an alkali metal is provided. The alkali metal in the presence of water at a point of contact of the device undergoes an exothermic reaction to generate heat in situ. The amount of heat generated is proportional to and/or limited by the amount (or moles) of water at the point of contact, and the heat generated is sufficient to achieve an increase in temperature at the point of contact to achieve a therapeutic or beneficial result. In one embodiment, the device is used for reducing sweat production in a subject suffering from excessive sweating or hyperhidrosis. In other embodiments, the device is used to substantially sterilize a surface or render a surface substantially aseptic.

Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described as well as for providing for other treatments. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance of cellulite. Treatments can include cooling a surface of a patient's skin and detecting at least one freeze event in the cooled skin. The treatment system can continue cooling the patient's skin after the freeze event(s) are detected so to maintain at least a partially frozen state of the tissue for a period of time.