The invention pertains to advances in real-time methods in nuclear magnetic resonance by offering a new dual-frequency dynamic nuclear polarization (DNP) method that uses a microwave beam to polarize the spins of electrons and concomitantly act as a NMR transmitter.

A method for killing or damaging cancerous cells in a living body comprising introducing glucose or other organic material as a biasing component into heating cancerous cells for purposes of destroying the cancerous cells with a second method of heating, such as by bombardment of energy from an external electromagnetic source, so as to raise the temperature of the tumor or cancerous cells to a degree that they are damaged or expire.

An apparatus for damaging or killing cancer cells in a living human body comprising a temperature monitoring apparatus that allows a user to monitor the temperature of a tumor and the surrounding tissue, such that when the tumor is at a temperature greater than the surrounding tissue, either because that is the nature of the tumor or because the tumor temperature has been raised through the introduction of an organic substance, an energy source may be used to elevate the temperature of the tumor above a critical temperature that damages or kills the tumor, but does not kill the surrounding non-cancerous cells because they start off at a lower temperature and are never allowed to go above the critical temperature that damages or kills those non-cancerous cells.

According to some embodiments, a system may treat blood outside the body of a patient. The system may include one or more pumps configured to draw blood from a patient into a fluid flow path at a rate, for example, of 5-7 liters per minute. The system may include one or more heat exchangers coupled to the fluid flow path and configured to heat the blood, for example, to a temperature above 42 degrees Celsius and below 43.2 degrees Celsius.

Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system is included having an electric field generating circuit configured to generate one or more electric fields and a control circuit in communication with the electric field generating circuit. The control circuit configured to control delivery of the one or more electric fields from the electric field generating circuit. The system can include two or more electrodes to deliver the electric fields to a site of a cancerous tumor within a patient and a temperature sensor to measure the temperature of tissue at the site of the cancerous tumor. The control circuit can cause the electric field generating circuit to generate one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz. Other embodiments are also included herein.

Exemplary embodiments of the present disclosure provide method and apparatus for effecting (e.g., lightening) an appearance of skin by cooling or freezing small separated surface regions of the skin to produce regions of local hypopigmentation. The width of the regions can be, for example, smaller than about 1 mm or 0.5 mm, and a distance between these frozen regions can be greater than about 3 times the width of the regions. An exemplary apparatus can be provided that includes a plurality of spatially-separated thermally conductive arrangements that can be affixed or otherwise coupled to a base. For example, the conductive arrangements can be regions of conductive material provided in or proximal to a thermal insulator, or thermally conductive protrusions affixed to the base. The conductive arrangements can be cooled and then contacted with the skin surface to produce the small regions of hypopigmentation.

A wearable back pad used to deliver targeted topical pain relief. The wearable vest or wrap product enables a person to apply topical pain-relievers right where it is needed in cases of unilateral neck or back pain or to the upper back area that is not reachable by the person's own hands. The back pad will act as a vehicle to hold and deliver the pain-relievers in the form of consumable patch or a pocket-insert that is placed by the users themselves in the specified area with the goal of maintaining the person's independence and decreasing the need for helping hands. Back pad consumables can hold and deliver anti-itch and skin care preparations to the back hence expanding this product's indication for use.

Exemplary embodiments of the present disclosure provide method and apparatus for effecting (e.g., lightening) an appearance of skin by cooling or freezing small separated surface regions of the skin to produce regions of local hypopigmentation. The width of the regions can be, for example, smaller than about 1 mm or 0.5 mm, and a distance between these frozen regions can be greater than about 3 times the width of the regions. An exemplary apparatus can be provided that includes a plurality of spatially-separated thermally conductive arrangements that can be affixed or otherwise coupled to a base. For example, the conductive arrangements can be regions of conductive material provided in or proximal to a thermal insulator, or thermally conductive protrusions affixed to the base. The conductive arrangements can be cooled and then contacted with the skin surface to produce the small regions of hypopigmentation.

A method includes generating a hyperthermia heat plan for tissue of interest, generating a hyperthermia adapted radiation therapy plan for the tissue of interest, controlling a heat source (126) to deliver heat to the tissue of interest according to the hyperthermia heat plan, and controlling a radiation source of a radiation therapy system (100) to deliver radiation to the tissue of interest according to the hyperthermia adapted radiation therapy plan. A system includes a radiation treatment planner (124) configured to generate a hyperthermia adapted radiation therapy plan for the tissue of interest, a radiation therapy system (100) configured to deliver radiation in accordance with the hyperthermia adapted radiation therapy plan, and a hyperthermia heat delivery system (126) configured to deliver heat in accordance with a hyperthermia plan.

The invention pertains to advances in real-time methods in nuclear magnetic resonance by offering a new dual-frequency dynamic nuclear polarization (DNP) method that uses a microwave beam to polarize the spins of electrons and concomitantly act as a NMR transmitter.