A compress for treating and preventing radiation dermatitis, comprising a reservoir layer configured to store and release a mixture of skin-cooling ingredients, wherein the compress is cold before applying to skin exposed to radiation therapy or becomes cold after applying to skin exposed to radiation therapy.

The invention is directed to a mouth piece for cooling of oral tissue of a patient during chemotherapy treatment. The mouth piece includes a cooling medium contained within the top element and the bottom element and able to retain a cooling environment within the mouth sufficient to reduce capillary blood flow to the patient's mouth. In one embodiment, an external chamber extends from the front of the mouth piece to house a cooling medium. A bladder is positioned inside the external chamber for storing a solution having a freezing temperature above the freezing point temperature of the cooling medium to assist in cooling the cooling medium.

The invention is directed to a mouth piece for cooling of oral tissue of a patient during chemotherapy treatment. The mouth piece includes a cooling medium contained within the top element and the bottom element and able to retain a cooling environment within the mouth sufficient to reduce capillary blood flow to the patient's mouth. In one embodiment, an external chamber extends from the front of the mouth piece to house a cooling medium. The external chamber can be configured so that it is removably attached to the mouth piece. A support device can be utilized to support the external chamber during use.

A composition for use in cooling therapy and treatment of chemically induced alopecia (CIA), said composition containing a reactive oxygen species (ROS) inhibitor.

Disclosed herein is a method to enable a user to use a hypothermia system to cool a body part involved in cancer therapy or in brain trauma. The method enables the user to operate the hypothermia system by her- or himself and still be mobile. The hypothermia system comprises a conformal cap system, a thermally conductive liquid located between the body part to be cooled and the cap system, thermal transfer fluids, phase change materials, thermally insulated cooler, physical measuring devices, mechanical and electrical components, a smart user interface device, a battery, and an uninterruptible power controller. The method allows a user to control the rate of and temperature of cooling down the body part, exhibits parameters associated with the process of cooling the body part, provides alerts if necessary, is portable and entirely self-managed. The hypothermia device is in communication with and can be controlled by an application installed on a smart device, such as a phone. The method of using the hypothermia system can help to eliminate hair loss caused by the side effects of certain chemotherapy treatments or to reduce the metabolic rate of ischemic tissue to prevent or minimize the severity of swelling.

Headwear (2) for removing heat from a person's scalp in order to prevent hair loss, comprising a body portion (4) for fitting over the scalp, an inlet (6) and an outlet (8), and fastener means (10) the headwear (2) being such that it opens to a flat condition when it is not in use on the person's head (12), and the body portion (4) comprises a plurality of internal walls (14) which define a passageway (18) through the body portion (4) from the inlet (6) to the outlet (8) whereby the cold fluid is able to circulate through the body portion (4), and the passageways (16) being such that they are expanded by the cold fluid and press against the person's scalp with a pressure which causes contact with the person's scalp and thereby to facilitate maximum cold transfer.

A non-user assisted, portable, entirely self-managed capable hypothermia device to eliminate hair loss caused by the side effects of certain chemotherapy treatments or to reduce the metabolic rate of ischemic tissue along with the severity of swelling is disclosed. The device consists of a conformal cap system, a thermally conductive liquid located between the body part to be cooled and the cap system, thermal transfer fluids, phase change materials, thermally insulated cooler, physical measuring devices, mechanical and electrical components, a smart user interface device, a battery, and an uninterruptible power controller.

The invention is directed to a mouth piece for cooling of oral tissue of a patient during chemotherapy treatment. The mouth piece includes a cooling medium contained within the top element and the bottom element and able to retain a cooling environment within the mouth sufficient to reduce capillary blood flow to the patient's mouth.

The invention relates to a device for use in the thermal therapy treatment of a selected region of the body of a human or of an animal, in particular for use in the treatment of tissue damage after surgical interventions, of injuries, of inflammations and of chronic diseases of the rheumatic type, and in particular for assisting chemotherapeutic treatments, comprising a temperature control device which is provided in order to control a temperature of a temperature control fluid, and a heat transfer device which is arranged to transfer heat to the selected region of the body, wherein the temperature control device is connected, in a fluid conducting manner, to the heat transfer device, and is further arranged to temper the heat transfer device with a heat transferring temperature control fluid flowing through the heat transfer device, and with a control device which is connected to the temperature control device and to the heat transfer device, wherein the control device is arranged to control the temperature control device, in order to cause the heat transfer device to be at least partially at an approximately uniform temperature in the region of a contact surface between the heat transfer device and the selected region of the body to be temperature controlled. The invention further relates to a method of operating the device.

A compress for treating and preventing radiation dermatitis, comprising a reservoir layer configured to store and release a mixture of skin-cooling ingredients, wherein the compress is cold before applying to skin exposed to radiation therapy or becomes cold after applying to skin exposed to radiation therapy.