Sensing devices including sensors such as flexible and stretchable fabric-based pressure sensors, may be associated with or incorporated in garments, such as socks, intended to be worn against a body surface (directly or indirectly). Specific manifestations of a sensing system incorporated in a sock substrate are described in detail. Dedicated electronic devices interface electrically with sensors through intermediate conductive traces, optional conductive bridges, conductive contacts provided in a mounting tab.

A bandage system lances a skin tag from a person's body and thereafter projects the wound created. The system has a base layer that is adhesively attached to the person such that the skin tag passes through an opening of the base layer. A cutter is located atop the base layer and uses a pair of blades that are squeezed together to cut the skin tag protruding through the opening. After cutting, a protective layer is adhered to the base layer such that a medicine laden absorbent pad on the protective layer overlays the opening on the base layer absorbing any blood from the wound and applying the medicine to the wound. Thereafter, the system is worn as a typical bandage.

A natural peptide comprising a cellular growth promoting fragment of a protein selected from SEQ ID NOs: 1 to 13, and a composition comprising a plurality of growth promoting peptides, is described. Also disclosed is the use of the peptides and compositions in prevention of ageing of human skin, treatment of diseases or conditions characterised by damaged epithelial cells or tissue such as colon cancer and peripheral inflammatory disorders, and wound treatment. Specific pea and rice protein derived peptides are described in SEQ ID NOs: 15 to 505, and 546 to 704.

Apparatuses, systems, and methods for treating a tissue site are described. The apparatus includes a dressing for treating a tissue site. The dressing includes a contact layer having a first side and a second side configured to be positioned adjacent to the tissue site. A plurality of holes extend through the contact layer from the first side to the second side. The dressing also includes a retainer layer coupled to the first side of the contact layer.

Dressings, systems, and methods for treating a tissue site are described. The dressing includes a contact layer having a first side and a second side. The first side of the contact layer configured to be positioned adjacent to the tissue site. The contact layer has a plurality of holes extending through the contact layer from the first side to the second side. The dressing includes a cover layer having a first side and a second side. The first side of the cover layer is coupled to the contact layer. The dressing also includes at least one retainer layer removably coupled to the second side of the cover layer.

Compositions and methods for inhibiting and interrupting biofilm formation, and for destabilizing established biofilms are provided, the novel compositions including polymeric resins and monomeric non-polymerizable and polymerizable resins. More particularly, the compositions and methods enable the protection and removal of biofilms from surfaces in the context of medical, consumer, domestic, food service, environmental and industrial applications, where the effects constitute beneficial and desirable biofilm attenuating activity.

An aerosol spray device includes a container having first and second fluid reservoirs disposed therein that are divided from one another. The first fluid reservoir holds a first mixture including a first aerosol propellant and a first part of a silicone based topical skin adhesive that is dissolved in the first aerosol propellant. The second fluid reservoir holds a second mixture including a second aerosol propellant and a second part of the silicone based topical skin adhesive that is dissolved in the second aerosol propellant. An aerosol spray dispensing system is connected with the container, which is configured to combine the first and second mixtures to form the silicone based topical skin adhesive and dispense the silicone based topical skin adhesive from the container as an aerosol spray.

Polyurethane material for indicating pH at a locus, preferably as indication of presence of microbes, comprising a polyurethane network having immobilised therein one or more hydrophilic copolymers, the or each said copolymer comprising: hydrophilic monomer; and indicating monomer, which provides an indication in response to a change in hydrophilic state of said hydrophilic monomer and/or copolymer; characterised in that the or each copolymer further comprises one or a plurality of ionisable groups or moieties or polymerisable monomers having one or more characteristic pKa values in the range 5 to 10 and which are responsive to pH at the locus in the range pH 5 to pH 10 and in that hydrophilic state of hydrophilic copolymer is dependent on ionisation of said ionisable groups, moieties or monomers; kit and device comprising the material and process for preparation thereof; and use in detecting or sensing microbes or pH.

A system for analyzing a wound fluid. The system includes a transparent layer, a membrane layer, and an indicator layer that contains a colorimetric or fluorescent indicator reagent for detecting pH, a nitrite, an enzyme, a reactive oxygen species, a reactive nitrogen species, a nucleic acid, or a combination thereof. The membrane layer is impermeable to blood clots and cellular debris and is permeable to wound fluid. Also provided are methods for analyzing a wound fluid and for detecting biological fluid on biomedical instruments and waste materials using the system.

An orthopedic prosthesis for stimulating bone growth may include a substrate having at least one bone-facing surface and at least one internal surface, at least one piezoelectric nanostructure coupled to the at least one bone-facing surface of the substrate, at least one charge storing material placed within the orthopedic prosthesis proximate the at least one internal surface, and an interconnect in electrical communication with the at least one piezoelectric nanostructure and the charge storing material. The at least one piezoelectric nanostructure may be configured to generate an electric charge in response to at least one mechanical force applied to the at least one piezoelectric nanostructure and the interconnect may be configured to transfer the electric charge to the at least one charge storing material to promote bone in-growth within the orthopedic prosthesis and/or on the at least one bone-facing surface.