Systems, apparatus, and methods related to wound closure devices comprising one or more microstructures are described herein. In some embodiments, the wound closure devices include a backing and a microstructure array. The microstructure array may include a first portion, a second portion, and a bridge portion. The first portion and the second portion each include one or more microstructures configured to penetrate tissue. Additionally, the first portion and the second portion each include one or more expandable portions such that the wound closure device is configured to expand in length. The wound closure device is configured to grip tissue surrounding a wound to either close the wound or secure the tissue in place.

Systems, apparatus, and methods related to wound closure devices comprising one or more microstructures are described herein. In some embodiments, the wound closure devices include a backing and a microstructure array. The microstructure array may include a first portion, a second portion, and a bridge portion. The first portion and the second portion each include one or more microstructures configured to penetrate tissue. Additionally, the first portion and the second portion each include one or more expandable portions such that the wound closure device is configured to expand in length. The wound closure device is configured to grip tissue surrounding a wound to either close the wound or secure the tissue in place.

An adhesion device incorporates element block assemblies partially disposed within an element support body having an engagement surface. Each element block assembly may include an element activation sheet, an element deployment sheet, a plurality of engagement elements, and an element transition mechanism operatively coupled to the engagement elements. The element transition mechanism is reversible to transition from a neutral configuration wherein the element activation sheet is substantially adjacent to the element deployment sheet, and an expanded configuration wherein the element activation sheet and the element deployment sheet are separated by a transition gap. The element support body, while each element transition mechanism is disposed in the neutral configuration, constrains each engagement element in a deployment state with a substantially straightened configuration perpendicular to the engagement surface and suitable for insertion into (or removal from) a target material. The element support body, while each element transition mechanism is disposed in the expanded configuration, constrains each engagement element in an engagement state eccentrically tensioned as the result of the transition gap into a reactive flexure to capture surrounding target material.

Systems, apparatus, and methods related to wound closure devices comprising one or more microstructures are described herein. In some embodiments, the wound closure devices include a backing and a microstructure array. The microstructure array may include a first portion, a second portion, and a bridge portion. The first portion and the second portion each include one or more microstructures configured to penetrate tissue. Additionally, the first portion and the second portion each include one or more expandable portions such that the wound closure device is configured to expand in length. The wound closure device is configured to grip tissue surrounding a wound to either close the wound or secure the tissue in place.

An adhesion device incorporating a plurality of element block assemblies which are partially disposed within an element support body having an engagement surface. Each element block assembly may include an element activation sheet, an element deployment sheet, a plurality of engagement elements, and an element transition mechanism which is operatively coupled to the engagement elements. The element transition mechanism is configured to reversible transition from a neutral configuration wherein the element activation sheet is substantially adjacent to the element deployment sheet, and an expanded configuration wherein the element activation sheet and the element deployment sheet are separated by a transition gap. The element support body being configured while each element transition mechanism is disposed in the neutral configuration to constrain each engagement element in a deployment state wherein each engagement element disposed in a substantially straightened configuration which is substantially perpendicular to the engagement surface and which is suitable for insertion into (or removal from) a target material.

A wound dressing having a perforated material including through-holes. The perforated material having a first and second face. A low adhesive resin coating at least the first face of the perforated material without closing the through holes. The perforated material is a knitted fabric or a woven fabric formed of a multifilament. The perforated material has an average opening area of the through-holes of 0.02 to 1.2 mm.sup.2 and an average number of through-holes of 40 to 220 cm.sup.2.

The present invention relates generally to wound closure device comprising one or more microstructures. The devices are designed such that the microstructures are able to grip the skin or tissue surrounding a wound, optionally closing the wound, or securing the tissue or skin in place. Also provided are wound closure systems that comprise one or more microstructure wound closure devices along with other components, such as protective covers and wound healing therapeutics. A variety of packaging specifications are disclosed, as is dispenser apparatus configured to enable simple one-handed application of the wound closure devices. Methods described herein provide for the closure of various wounds with the wound closure devices and systems.

The present invention relates generally to wound closure devices comprising one or more microstructures. The devices are designed such that the microstructures are able to grip the skin or tissue surrounding a wound, optionally closing the wound, or securing the tissue or skin in place. Also provided are wound closure systems that comprise one or more microstructure wound closure devices along with other components, such as protective covers and wound healing therapeutics. A variety of packaging specifications are disclosed, as is a dispenser apparatus configured to enable simple one-handed application of the wound closure devices. Methods described herein provide for the closure of various wounds with the wound closure devices and systems.

Systems, apparatus, and methods related to wound closure devices comprising one or more microstructures are described herein. In some embodiments, the wound closure devices include a backing and a microstructure array. The microstructure array may include a first portion, a second portion, and a bridge portion. The first portion and the second portion each include one or more microstructures configured to penetrate tissue. Additionally, the first portion and the second portion each include one or more expandable portions such that the wound closure device is configured to expand in length. The wound closure device is configured to grip tissue surrounding a wound to either close the wound or secure the tissue in place.

An adhesion device incorporating a plurality of element block assemblies which are partially disposed within an element support body having an engagement surface. Each element block assembly may include an element activation sheet, an element deployment sheet, a plurality of engagement elements, and an element transition mechanism which is operatively coupled to the engagement elements. The element transition mechanism is configured to reversible transition from a neutral configuration wherein the element activation sheet is substantially adjacent to the element deployment sheet, and an expanded configuration wherein the element activation sheet and the element deployment sheet are separated by a transition gap. The element support body being configured while each element transition mechanism is disposed in the neutral configuration to constrain each engagement element in a deployment state wherein each engagement element disposed in a substantially straightened configuration which is substantially perpendicular to the engagement surface and which is suitable for insertion into (or removal from) a target material.