A system for partial ossicular replacement with controllable stapedial engaging function is described; a respective process of manufacturing a partial ossicular replacement prosthesis with controllable stapedial engaging function and a partial ossicular replacement prosthesis are further described; the system comprises: a partial ossicular replacement prosthesis comprising a stapedial part and a tympanic part, an applicator device comprising a handpiece, an essentially planar static face, an elongated essentially cylindrically shaped plunger; the process comprises: providing a preform of at least stapedial part, forming a plurality of elongated cuts, shaping a centrical portion, shaping a distal portion; the partial ossicular replacement prosthesis comprises a stapedial part and a tympanic part.

Described are stent grafts with at least on branch and mandrels used to form the stent grafts. Methods of making and using them are also described.

It is an object to provide a woven fabric which can stably form a folding shape superior in shape retention and followability and which can be sewn while maintaining the folding structure, and also to provide a method for manufacturing the same. There is provided a woven fabric having pleats, wherein the height of the pleats is 2 to 10 times the average diameter of yarns arranged in the same direction as the pleats.

A manufacturing process forms a bored hollow lumen. The manufacturing process includes providing a solid rod of a bioresorbable material and boring a hole axially through the solid rod. The manufacturing process also includes modifying surface defects formed on a luminal surface by the boring, the luminal surface defining the hole, thereby forming the bored hollow lumen. A bored hollow lumen includes a lumen wall including a bioresorbable material. The lumen wall has an abluminal surface and a luminal surface. The luminal surface defines a bore through the bored hollow lumen. The bioresorbable material has a uniform crosslinking density.

An intraocular device that includes a fluid lens is provided. The fluid lens has an anterior side and posterior side that can be coupled together to form a closed cavity therebetween that can be filled with a liquid material. A channel can be formed in the posterior side that is configured to receive a joining substance that bonds the anterior side to the posterior side and inhibit the unintended spread of the joining substance. A syringe can be extended through a port in the fluid lens to flow liquid material into the closed cavity. Subsequently, a plug can be inserted into the port to prevent the escape of the liquid material.

In one embodiment, the present disclosure may be a method for preparing a soft tissue graft, comprising: passing a suture material through the soft tissue graft adjacent to a graft support filament at a first longitudinal location along the filament and graft, such that the suture material passes through the graft on a first side of the filament; passing the suture material over the filament and back through the graft adjacent to the filament at a second longitudinal location spaced longitudinally along the filament and graft from the first longitudinal location, such that the suture material passes through the graft on the first side of the filament; and tensioning the suture material to secure the filament to the graft along a length of the suture material between the first longitudinal location and the second longitudinal location.

A biodegradable flow diverting device (BFDD) that will regulate blood flow into an aneurysmal sac, act as a scaffold for endothelization at the neck of an aneurysm, and degrade after successful dissolution of aneurysm and remodeling of blood vessel. This BFDD and associated fabrication method have the following features: (1) This is a non-braided FDD. The pore shapes, sizes, architectures (especially at the inlet and outlet of the pores), pore densities and porosities can be controlled for the optimum performance depending on the blood vessel and aneurysmal morphologies from patient MRI images, (2) BFDD is developed on a rotary arm with programmable variable speed and diameter in conjunction with a micromotion stage (3) Fabrication system can take any material including blended/composite biomaterials by adjusting temperature of the electro-melt extruder/needle and (4) Fabrication system is compatible with CAM (computer aided manufacturing) software and able to operate based on the adapted G-code.

Embodiments of the present invention provide a unique new approach to generating operating condition information used for assessing flow assurance and structural integrity. More specifically, apparatuses, systems and sensor housing assemblies configured in accordance with embodiments of the present invention utilize fiber optic sensors for enabling monitoring of operating condition information within one or more elongated tubular members within a subsea environment. To this end, such fiber optic sensors connected by lengths of optical fiber are strategically placed at a plurality of locations along a length of each elongated tubular member thereby allowing critical operating conditions such as strain, temperature and pressure of the elongated tubular member and/or a fluid therein to be monitored. A viscous media is used for mitigating attenuation associated with exposure of optical fiber exposed to forces generated by pressure within the subsea environment.

The invention relates to a knit having barbs protruding outwards from both faces obtained by knitting yarns of biocompatible material in guide-bars B2, B3 and B4 of a knitting machine, wherein the knitting patterns followed by guide-bars B2 and B3 involve at least two needles and produce an arrangement of yarns defining two faces of the knit, the knitting pattern followed by guide-bar B4 making stitches generating loops protruding outwards from each of the faces of the knit, guide-bar B4 being threaded with a hot-melt monofilament yarn, heat-setting the knit, forming barbs by cutting the loops via melting.

The present invention relates to large scale manufacture of nanoscale microsheets for use in applications such as wound healing or modification of a biological or medical surface.