The present invention relates to a stent graft, comprising: a hollow stent graft body having a lumen extending from one end of the stent graft body to the respective other end of the stent graft body, an expandable reservoir provided on an interior of the stent graft body, the expandable reservoir being covered with a separation layer on a side of the expandable reservoir facing the lumen, the expandable reservoir being arranged so as to swell when exposed to blood, the separation layer being arranged to prevent the expandable reservoir from being exposed to blood flowing through the lumen, the separation layer being arranged so that it can selectively expose the expandable reservoir to blood to cause the expandable reservoir to swell.

A delivery apparatus for controlling implantation of a prosthetic heart valve includes a handle housing and a release mechanism mounted on the handle housing. The release mechanism can be operably coupled to at least one actuation shaft. Actuation of the release mechanism can cause a distal end portion of the actuation shaft to be connected to or released from the prosthetic heart valve. The handle also includes an indicator tab configured to indicate whether the actuation shaft if connected to or released from the prosthetic heart valve.

A system for partial ossicular replacement with controllable stapedial engaging function is described; a respective process of manufacturing a partial ossicular replacement prosthesis with controllable stapedial engaging function and a partial ossicular replacement prosthesis are further described; the system comprises: a partial ossicular replacement prosthesis comprising a stapedial part and a tympanic part, an applicator device comprising a handpiece, an essentially planar static face, an elongated essentially cylindrically shaped plunger; the process comprises: providing a preform of at least stapedial part, forming a plurality of elongated cuts, shaping a centrical portion, shaping a distal portion; the partial ossicular replacement prosthesis comprises a stapedial part and a tympanic part.

Prosthetic ring valve assemblies are disclosed. A prosthetic valve ring assembly includes an outer tube and a plurality of anchors. The outer tube includes a plurality of windows. The plurality of anchors are positioned inside the outer tube and about a perimeter of the outer tube. The plurality of anchors are configured to be emitted from the plurality of windows in order to anchor the prosthetic valve ring assembly to annulus tissue of a patient.

A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.

Systems, devices and methods related to various heart valve implants and for delivery of those heart valve implants are described. The implants may be used to re-size a native valve annulus or to replace a native heart valve. The implants include a re-sizable frame having angled struts. Anchors secure the implant to tissue and collars are used to decrease the angle between the struts and contract the frame. The implant thus expands from a first size inside of a delivery catheter, to a second and larger deployed size inside the heart to engage and anchor with the tissue, and then to a third and contracted size to re-size the annulus and/or provide a secure fit for a replacement heart valve. Various delivery systems including imaging capabilities for precise delivery, positioning and anchoring of the various implants are further described.

An orthopedic device includes a hinge assembly, a frame having first and second frame components spaced apart from and connected to one another by the hinge assembly, a strap system extending between medial and lateral sides of the first frame component, and at least one tensioning element. The at least one tensioning element has a first end secured to the strap system and a second end coupled to the hinge assembly. Articulation of the hinge assembly pulls the strap system toward the frontal plane by the at least one tensioning element.

A prosthetic heart valve includes a frame, a valve, and an expansion element. The frame is movable between contracted and expanded configurations and includes first struts and second struts non-hingedly coupled together. The second struts are configured to pivot relative to the first struts as the frame moves between the contracted and expanded configurations. The valve is coupled to the frame and includes leaflets. The expansion element extends through a lumen of the first struts. The expansion element is slidable relative to the lumen of the first struts and is configured to move the frame incrementally from the contracted configuration and the expanded configuration and from the expanded configuration to the contracted configuration.

A method of placing a valve in a tubular organ including the steps of delivering an expandable tubular adapter to a site within the tubular organ, wherein the adapter includes an enclosed volume surrounded by an outer wall that is spaced from an inner wall, and first and second end walls. The method further includes expanding the outer wall relative to the inner wall so that the outer wall contacts the tubular organ, and placing a valve within the inner wall of the adapter. The method may further include inserting material into the enclosed volume of the adapter to expand the outer wall relative to the inner wall, which material may include liquid or gel. Alternatively, the valve may be positioned within the inner wall prior to the adapter being delivered to the desired site.

A size adjustable cover used for soft tissue reinforcement which is adapted to envelop an implantable device, such as a breast implant, in a surgical application. The cover is formed using a circular two-dimensional implantable matrix material having an inner circle and a plurality of fringes which radiate circumferentially from the inner circle. The implantable device is positioned upon the inner circle, and the plurality of fringes are folded inwardly to form an overlapping implant pocket which envelops the implantable device. Each fringe further has a punched opening, allowing a loop of suture thread to link each fringe together. Certain fringes are excluded from the loop to create stabilization tabs which radiate from the inner circle and are attached to a site of host implantation to stabilize the cover and the implantable device within.