The present disclosure relates to an implant component (10, 20) having at least one connecting portion (30, 60), the connecting portion being at least partly coated with a Zr coating and the coating having a thickness of 1-20 μm, preferably 1-6 μm. The present disclosure further relates to a modular endoprosthesis comprising an implant component, to the use of a Zr coating to prevent crevice corrosion and/or fretting corrosion, and to the use of an implant component in patients suffering from a metal allergy.

Implants for prevention of cold welding, corrosion and tissue overgrowth on surfaces between medical implant components include a first medical implant component having a first implant contact surface, a second medical implant component having a second implant contact surface positionally interfacing with the first implant contact surface of the first medical implant and a separation coating material on at least one of the first implant contact surface and the second implant contact surface. Methods for prevention of cold welding and/or corrosion between and/or tissue/bone overgrowth on implant components and methods of sealing an interface between a first implant component and a second implant component in a prosthesis system are also disclosed.

Stents formed from dissimilar materials configured to control tissue growth. A stent may be formed from a composite wire helically wound into a stent having a tubular configuration. The composite wire includes a first wire and a second wire coupled together, the first and second wires being formed from dissimilar metals such that a potential difference is formed when the dissimilar metals are exposed to bodily fluids. The potential difference is configured to inhibit cell proliferation and thereby control tissue growth around the stent after implantation. A stent may be formed from a hollow composite wire including an inner member that includes first and second longitudinal strips formed from dissimilar metals. A stent may be formed from a composite wire having a plurality of windows along a length of the composite wire. An insert formed from a dissimilar metal is disposed within each window of the plurality of windows.

Implantable devices disclosed herein may be configured to modulate the localized pH at an implantation site of the implantable device. By controlling, modulating, or otherwise adjusting the localized pH, various benefits can be achieved, such as controlling cell proliferation. The implantable device may include a body and one or more metallic features. Generally, the implantable device forms a galvanic cell such that a first metallic feature is configured to be preferentially oxidized to alter the localized pH environment in the vicinity of the implantable device.

Implants for prevention of cold welding, corrosion and tissue overgrowth on surfaces between medical implant components include a first medical implant component having a first implant contact surface, a second medical implant component having a second implant contact surface positionally interfacing with the first implant contact surface of the first medical implant and a separation coating material on at least one of the first implant contact surface and the second implant contact surface. Methods for prevention of cold welding and/or corrosion between and/or tissue/bone overgrowth on implant components and methods of scaling an interface between a first implant component and a second implant component in a prosthesis system are also disclosed.

Methods for prevention of cold welding and/or corrosion between and/or tissue/bone overgrowth on implant components may include obtaining a first medical implant component having a first implant contact surface; obtaining a second medical implant component having a second implant contact surface, the second implant contact surface adapted for placement into contact with the first implant contact surface, the first implant contact surface and the second implant contact surface encompassing all points of contact between the first medical implant component and the second medical implant component; and applying a nonmetallic biocompatible separation coating material having a wax formulation on at least one of the first implant contact surface and the second implant contact surface, the nonmetallic biocompatible separation coating material separates the first implant contact surface from the second implant contact surface at all of the points of contact between the first medical implant component and the second medical implant component. Medical implant for prevention of cold welding, corrosion and tissue overgrowth on medical implant components are also disclosed.

Disclosed is an absorbable iron-based instrument (10). The absorbable iron-based instrument includes an iron-based matrix (100), a zinc-containing protective layer (200), a corrosion-promoting layer (300) and a drug controlled-release layer (400); the iron-based matrix (100) is provided with an outer wall (110), an inner wall (120) and a side wall (130); the zinc-containing protective layer (200) covers at least the outer wall (110) and the inner wall (120) of the iron-based matrix (100); the corrosion-promoting layer (300) fully covers the zinc-containing protective layer (200); the drug controlled-release layer (400) partially covers at least the corrosion-promoting layer (300); the corrosion-promoting layer (300) and the drug controlled-release layer (400) each contain degradable polymers; the weight-average molecular weight of the degradable polymers in the corrosion-promoting layer (300) is greater than the weight-average molecular weight of the degradable polymers in the drug controlled-release layer (400); and the thickness ratio of a portion of the zinc-containing protective layer (200) that is located at the inner wall (120) to a portion of the corrosion-promoting layer (300) that is located at the inner wall (120) is greater than the thickness ratio of a portion of the zinc-containing protective layer (200) that is located at the outer wall (110) to a portion of the corrosion-promoting layer (300) that is located at the outer wall (110). The corrosion behavior of the absorbable iron-based instrument (10) meets the requirements of clinical use, and the occurrence of adverse histological reactions is rare or avoided.

Stents formed from dissimilar materials configured to control tissue growth. A stent may be formed from a composite wire helically wound into a stent having a tubular configuration. The composite wire includes a first wire and a second wire coupled together, the first and second wires being formed from dissimilar metals such that a potential difference is formed when the dissimilar metals are exposed to bodily fluids. The potential difference is configured to inhibit cell proliferation and thereby control tissue growth around the stent after implantation. A stent may be formed from a hollow composite wire including an inner member that includes first and second longitudinal strips formed from dissimilar metals. A stent may be formed from a composite wire having a plurality of windows along a length of the composite wire. An insert formed from a dissimilar metal is disposed within each window of the plurality of windows.

The present disclosure relates to a loop vascular device and a method to retrieve said device from the body vessel of a patient. The loop vascular device comprises a loop having a first portion extending distally to a splitting portion, and a second portion also extending distally to the splitting portion, defining a close state of the loop. The splitting portion may be split such that the first portion is separated from the second portion when in the body vessel, defining an open state of the loop. In the open state, the loop may be easily retrieved through ingrowth in the body vessel, reducing or eliminating possible negative effects to the vessel wall.

The present disclosure relates to a loop vascular device and a method to retrieve said device from the body vessel of a patient. The loop vascular device comprises a loop having a first portion extending distally to a first bar, and a second portion extending distally to a second bar. In a close state of the loop, the first and second bars are maintained or housed inside a first cannula. The first cannula may be in contact with a second cannula. Upon desiring to open the loop, the physician may separate the first cannula from the second cannula, allowing the bars to exit the first cannula and disconnect from each other, defining the open state of the loop. In the open state, the loop may be easily retrieved through any ingrowth in the body vessel.