A delivery apparatus for controlling implantation of a prosthetic heart valve includes a handle housing and a release mechanism mounted on the handle housing. The release mechanism can be operably coupled to at least one actuation shaft. Actuation of the release mechanism can cause a distal end portion of the actuation shaft to be connected to or released from the prosthetic heart valve. The handle also includes an indicator tab configured to indicate whether the actuation shaft if connected to or released from the prosthetic heart valve.

An intraocular device that includes a fluid lens is provided. The fluid lens has an anterior side and posterior side that can be coupled together to form a closed cavity therebetween that can be filled with a liquid material. A channel can be formed in the posterior side that is configured to receive a joining substance that bonds the anterior side to the posterior side and inhibit the unintended spread of the joining substance. A syringe can be extended through a port in the fluid lens to flow liquid material into the closed cavity. Subsequently, a plug can be inserted into the port to prevent the escape of the liquid material.

Devices and methods for gastrointestinal bypass are described. A gastrointestinal bypass device includes a gastrointestinal cuff and a gastrointestinal sleeve. The cuff may be configured to be attached in the esophagus, and may be sufficiently flexible to expand and collapse to conform with the inside of the esophagus to allow the esophagus to function substantially normally. The sleeve is configured to be coupled to the cuff, and may be made of a material that is floppy or flaccid but does not substantially expand radially.

Stent delivery device including an inner member having a distal tip, a stent support member, and a stent disposed over a stent receiving region of the stent support member. An elongated outer sheath is slidably disposed over the inner member and the stent. The stent delivery device includes a distal junction removably coupling the distal end of the outer sheath to the distal tip, where the distal junction is actuatable to decouple the outer sheath from the distal tip. The stent delivery device includes a proximal junction removably coupling a distal portion of the outer sheath to a proximal portion of the outer sheath, where the proximal junction is actuatable to decouple the distal portion of the outer sheath from the proximal portion of the outer sheath. The distal and proximal junctions may be separately actuatable by rotating the inner member relative to the proximal portion of the outer sheath.

A multi-piece IOL assembly is provided that includes a platform and an optic. The platform has an inner periphery surrounding an inner zone of the platform. The optic has an optical zone, an outer periphery and a retention mechanism disposed on the outer periphery. The optic is configured to be disposed in the inner zone of the platform and to extend to a location between the inner periphery and the outer periphery of the platform to be secured to the platform at the location. The platform can be secured to an inner periphery of the eye or can be formed into a natural lens by cutting the lens using a laser or other energy source.

A selectively expanding spine cage has a minimized cross section in its unexpanded state that is smaller than the diameter of the neuroforamen through which it passes in the distracted spine. The cage conformably engages between the endplates of the adjacent vertebrae to effectively distract the anterior disc space, stabilize the motion segments and eliminate pathologic spine motion. Expanding selectively (anteriorly, along the vertical axis of the spine) rather than uniformly, the cage height increases and holds the vertebrae with fixation forces greater than adjacent bone and soft tissue failure forces in natural lordosis. Stability is thus achieved immediately, enabling patient function by eliminating painful motion. The cage shape intends to rest proximate to the anterior column cortices securing the desired spread and fixation, allowing for bone graft in, around, and through the implant for arthrodesis whereas for arthroplasty it fixes to endpoints but cushions the spine naturally.

Aortic root replacement grafts, systems and methods for implanting an aortic root replacement graft are disclosed. The graft includes a tubular portion; a bulged portion with a first end and a second end, wherein the second end of the bulged portion is coupled to a first end of the tubular portion; a cuff portion coupled to the first end of the bulged portion; and at least one side arm coupled to and extending from the bulged portion. Methods for implanting an aortic root replacement graft with two side arms are also disclosed.

A method of providing support in an aortic region. The method includes wrapping a landing band around an outside of a portion of an aortic vessel in a vicinity of a sinotubular junction (STJ) to form a wrapped portion of the aortic vessel. The method further includes securing the landing band to form a secured landing band. The method also includes endovascularly delivering a stent graft in a radially constricted configuration into the aortic vessel. The method also includes deploying the stent graft to a radially expanded configuration such that the stent graft contacts the wrapped portion of the aortic vessel. The method also includes connecting the stent graft in the radially expanded configuration to the secured landing band.

Prosthesis (1) comprising a patch (2) made of biocompatible material, said patch having a generally plane geometric shape that defines two opposite faces, a centre, a length and a width of said patch, characterized in that said patch is provided, on one (2a) of its faces, with a single marking means (3) designed to indicate both the centre (C) of the patch and also the longitudinal direction of said patch.

An accommodative intraocular lens includes an optic body having an optical power changing structure. There are two supporting structures disposed opposite one another about the optic body, each supporting structure configured to be connected at a distal end to a ciliary body after implantation in an eye of a patient and connected at a proximal end to the optic body. The two supporting structures are a zeroing supporting structure and an actuating supporting structure. The zeroing supporting structure is configured to not change the optical power of the optic body in an installation mode and an operation mode of the accommodative intraocular lens. An actuating supporting structure is configured to not change the optical power of the optic body in the installation mode but is configured to change the optical power of the optic body in the operation mode of the accommodative intraocular lens.