An intervertebral implant may include a shaft having a proximal end, a distal end, a longitudinal axis, a minor diameter, and a helical thread disposed about the shaft along the longitudinal axis between the proximal end and the distal end of the shaft. The helical thread may include a major diameter and a concave undercut surface angled towards one of the proximal end and the distal end of the shaft. The intervertebral implant may be implanted within an intervertebral space between a superior vertebral body and an inferior vertebral body. A ratio of the major diameter to the minor diameter may be less than 1.50. The concave undercut surface may engage the superior vertebral body and the inferior vertebral body and may be shaped to resist at least one force transmitted between the superior vertebral body and the inferior vertebral body to stabilize the intervertebral space.

A bone disunion instrument system may include a first bone pin, a second bone pin, and a guide block. The guide block may include first and second bone pin holes to receive the first and second bone pins, and a window intermediate the first and second bone pin holes. The first bone pin may be anchored in a first bone portion and inserted through the first bone pin hole, and the second bone pin may be anchored in a second bone portion and inserted through the second bone pin hole to impart a compression or distraction force on a bone disunion between the first and second bone portions. The window formed through the guide block may provide access for an implant placed through the window to stabilize the bone disunion while the bone disunion is placed under a compression or distraction force.

A bone disunion fastener may include a fastener shaft, a helical thread, and a bone staple. The helical thread may include a concave undercut surface oriented towards one end of the fastener shaft. The bone staple may include a first bone-engaging feature, a second bone-engaging feature, and a middle portion with an opening. The bone disunion fastener may be implanted along a disunion between a first bone portion and a second bone portion. The concave undercut surface may be shaped to resist at least one force transmitted between the first bone portion and the second bone portion to stabilize the disunion. The first bone-engaging feature may engage the first bone portion and the second bone-engaging feature may engage the second bone portion to couple the bone staple to the bone portions and resist at least one force transmitted between the bone portions to stabilize the disunion.

A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.

Systems and methods are described for correcting sagittal imbalance in a spine including instruments for performing the controlled release of the anterior longitudinal ligament through a lateral access corridor and hyper-lordotic lateral implants.

An alloprosthetic composite implant comprising includes a structural porous scaffold having a pore density profile corresponding to a density profile of bone to be replaced. A plurality of cells are seeded within pores of the porous scaffold and grown by incubation. The cells may include osteoblasts and/or stem cells to form the structure of the implant, and one or more cartilage layers may be grown on top of the scaffold. The pore density profile of the scaffold may be formed based on one or both of the bone density profile of the bone to be removed, and the bone density profile of the native bone that will be in contact with the alloprosthetic implant. A robot may be employed reo resect the native bone and also to shape the alloprosthetic implant to fit into place in the native bone.

Systems and methods are described for correcting sagittal imbalance in a spine including instruments for performing the controlled release of the anterior longitudinal ligament through a lateral access corridor and hyper-lordotic lateral implants.

An expandable interspinous process fixation system capable of restoring spinal stability and facilitating fusion. In one embodiment, the expandable interspinous process fixation system includes a central ramp, a first endplate, and a second endplate, the central ramp capable of being moved in a first direction to move the first and second endplates outwardly and into an expanded configuration. Each endplate supporting fixed and/or adjustable spinous process engaging plates.

The present invention relates to an expandable implant for engagement between vertebrae generally comprising an inner member, outer member, and gear member positioned coaxial with respect to each other such that the inner and outer members are moveable relative to each other along an axis. The gear member is axially fixed to the outer member and freely rotatable with respect to the outer member and the gear member threadedly engages a threaded portion of the inner member to translate inner member along the axis. The implant is configured to engage the vertebrae in a predetermined alignment and the gear member includes gear teeth exposed to the exterior and configured to be accessible by a tool member at a plurality of angular positions around the perimeter of the implant device.

The present invention provides an expandable fusion device capable of being installed inside an intervertebral disc space to maintain normal disc spacing and restore spinal stability, thereby facilitating an intervertebral fusion. In one embodiment, the fusion device includes a central ramp, a first endplate, and a second endplate, the central ramp capable of being moved in a first direction to move the first and second endplates outwardly and into an expanded configuration. The fusion device is capable of being deployed down an endoscopic tube.