An IV adapter to allow for the mixing of multiple compatible medications with one another using a single bag of intravenous fluid. The IV adapter has multiple arms extending which gives rise to the ability to mix multiple medications. There is a spike within each arm to puncture the medication. The plurality of arms have built in mechanisms to control the flow of the medication and stop it from flowing in a certain direction. There are connections at the end of each arm allowing for a tight seal to be made to prevent any medication from leaking out of the IV line.

Various embodiments are disclosed herein related to fluidic connections for modules useable in combinatorial drug delivery devices. The fluidic connections allow for variable flow paths to be defined for serially-connected, and base-tray mounted, modules.

A valving arrangement is provided herein for regulating fluidics of modules usable in a combinatorial drug delivery device. The valving includes a slidable piston valve, adjustable to selectively seal an outlet path from a drug vial and a sealing port, in parallel to a vent, for selectively sealing an inlet path to the drug vial. Advantageously, the subject invention allows for applied negative pressure to adjust the valving to allow flow between serially-connected modules forming a drug delivery device.

A pre-filled medical delivery system can have a blow-fill-seal (BFS) component and a connection assembly. The BFS component can have first and second chambers, and first and second sealed ports. Each chamber can have a respective liquid agent therein. Each sealed port can be in fluid communication with a respective one of the chambers. The connection assembly can be constructed for coupling to the BFS component. When coupled to the BFS component, the connection assembly can breach the seals of the first and second ports and provide fluid communication therebetween. The disclosed systems, when assembled, can combine the liquid agents from the first and second chambers of the BFS component and deliver the combination as a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) to a patient.

A drug mixing device is configured to mix a first content in a liquid form in a first container and a second content in a liquid or powder form in a second container. According to an embodiment of the present disclosure, a first flow path extending from one end configured to allow a liquid inside the first container to flow into the first flow path through the one end to the other end configured to allow a liquid inside the second container to flow into the first flow path through the other end, a second flow path branching from a first branch point located on the first flow path and extending to an outlet port, and a third flow path extending to connect a second branch point located on the second flow path and a third branch point located on the first flow path are formed in the drug mixing device.

A fluid transfer device for transferring fluid between a supply reservoir and a fill reservoir includes a metering reservoir and a manifold that forms at least part of a first channel that is fluidly connected with the metering reservoir. The first channel comprises a first cannula extending from the manifold. The manifold forms at least part of a second channel fluidly connected with the metering reservoir. The second channel comprises a second cannula extending from the manifold. A third channel extends through the manifold and comprises a third cannula having a first end proximate a distal end of the first cannula and a second end proximate a distal end of the second cannula. A first check valve is disposed within the first channel and a second check valve is disposed within the second channel.

Disclosed is a transfer device for use in reconstituting dry drugs and for diluting liquid drugs in drug containers. The transfer device includes a multi-port manifold and a connector suitable to be attached to a drug container, a first conduit to transfer a liquid entering an inlet port of the manifold through the connector and into the drug container, and a second conduit to transfer a gaseous fluid through the connector to an outlet port of the manifold. Also disclosed is a closed liquid transfer system which includes the transfer device, a tube connectable to the inlet port for transporting a liquid to the transfer device, a tube connectable to the outlet port for transporting the gaseous fluid away from the transfer device, and a gas collection container to collect the gaseous fluid in the gas transporting tube.

The present relates to a component mixing device comprising a central unit (10) and a disposable cartridge, said central unit (10) comprising a control unit, a plurality of vial positioning elements (13) and a cavity 14 for receiving said disposable cartridge, and said disposable cartridge (20) comprising a tubing circuitry adapted to put the components housed in said plurality of vials into communication for mixing, characterized in that the mixing device is adapted to put each vial into communication with each other through said tubing circuitry of said disposable cartridge (20) and mixing said components through an compressed air mechanism (12) located in said central unit (10) and controlled by said control unit.

Various embodiments are generally directed to fluid container adapters that couple with a fluid container and enable different systems, such as endoscopic systems, to access the contents of the fluid container, such as via a tubing set. Several embodiments are particularly directed to a fluid container adapter that punctures a fluid container to couple with and gain access to the contents of the fluid container. In one embodiment, for example, a platform may be used to support a fluid container as one or more penetration members attached to a crossmember are advanced into the fluid container along rails connected between the platform and the crossmember. In such embodiments, the one or more penetration members may include lumens to enable a tubing set to access the contents of the fluid container.

An assembly for mixing drug components includes a housing to at least partially hold a first drug component container and a second drug component container. The assembly also includes a transfer member having first and second ends to fluidly couple the respective first and second drug component containers. The assembly further includes a pressure member to fluidly couple the first drug component container to a pressure generation chamber. In addition, the assembly includes an energy storage member to generate pressure in the pressure generation chamber to transfer a fluid from the first drug component container into the second drug component container. Moreover, the assembly includes an exit member to fluidly couple the second drug component container to an exterior of the assembly.