A container adapter (1) for a medical delivery device, which medical delivery device has a container seat for holding a container in a predefined position, a dosage chamber, a dosing mechanism to transfer a liquid from the container held in the container seat to the dosage chamber and a lock mechanism adapted to prevent operation of the dosing mechanism when no container is held in the container seat and to allow operation of the dosing mechanism when the container is held in the container seat. The container adapter (1) comprises an adapter container seat (11), a joint structure (12) and an unlock mechanism. The adapter container seat (11) is configured to hold a container in a predefined position. The joint structure (12) is configured to be detachably positioned in the container seat of the medical delivery device and to connect the adapter container seat (11) to the dosing mechanism of the medical delivery device (3) when the joint structure (12) is positioned in the container seat of the medical delivery device (3). The unlock mechanism is configured to activate the lock mechanism of the medical delivery device when the joint structure (12) is positioned in the container seat of the medical delivery device and the container is properly held in the adapter container seat (11), and to prevent activation of the lock mechanism of the medical delivery device when the container is not properly held in the adapter container seat (11).

A system for the preparation and dispensing of a mixture comprising: i) a container (2) for a first substance; ii) a closure cap (4) of the container (2); iii) a capsule (3) applied to a mouth (20) of the container (2) and comprising: —a containment chamber (31) for the second substance; —a perforation means (32) for perforating the chamber (31) and the cap (4); said system (1) taking on a rest configuration wherein the inside of the container (2) and the inside of the containment chamber (31) are fluid-dynamically separated and an operating configuration wherein said perforation means (32) extends into the chamber (31) and passes through the cap (4); iv) a mixture withdrawal mouth (5) which is part of said container (2) or of said capsule (3); said withdrawal mouth (5) being intended to dispense the mixture of the first and second substances outside the system. The cap (4) may or may not be part of the capsule (3). A movement of said chamber (31) brings about the passage from the rest configuration to the operating configuration; said perforation means (32) comprising a conduit (320) which in said operating configuration places the inside of the container (2) in communication with the inside of the chamber (31). The withdrawal mouth (5) in the rest configuration, is in fluid communication with the chamber (31) or the container (2).

A sealed assembly for pill crushing and delivering and a method for using thereof are provided. The assembly includes: a connecting valve with different diameters, including a first end, a valve and a second end provided with a syringe-abutting interface, wherein, an opening diameter of the first end is larger than that of the second end; and a pill-crushing carrier including a sealed cavity having only one filling-in opening, the pill-crushing carrier has a first state when separated from the connecting valve and the filling-in opening is exposed for delivering pills into the carrier, and a second state when the filling-in opening is connected to the first end of the connecting valve, crushed and dissolved pill powders in the sealed cavity can be taken out through the connecting valve. The assembly can crush pills and dissolve powders in a sealed cavity, deliver powder-dissolved liquid and prevent powders from dispersing.

A connector for forming a fluid flow pathway by connection with a reciprocal connector. Both the connector and reciprocal connector include a fluid flow blockage part sheathed within an axially compressible sheath part. A first bearing surface receives an urging force to retract the blockage part axially along the sheath part. A terminal end of the sheath part defines a second bearing surface containing a fluid flow opening with the fluid flow blockage part retractably therein. A first chassis part includes a first catch part. A second chassis part includes a second catch part and a third bearing surface spaced from the second catch part along the second chassis part. Retraction of the blockage part forms a fluid flow pathway not sooner than immediately when the openings meet to allow fluid transfer the openings avoiding fluid leakage between connected connectors.

A method of powderizing a dry cake pharmaceutical drug product for injection within a vial may include securing a vial containing a dry cake pharmaceutical drug product for injection to a shaker device and powderizing the dry cake pharmaceutical drug product within the vial by shaking the vial with the shaker device operated at between about 100 to about 5000 cycles per minute for between about 10 minutes and about 1 hour.

A method for performing a medical procedure requiring effective, reliable and foolproof delivery of controlled amounts of a medical grade gas to a patient includes providing a compressed gas cylinder having a weight with medical grade gas sealed therein of at least twelve grams and not greater than fifty grams. The method also includes connecting the compressed gas cylinder to an integrated compressed gas unit including a regulator valve assembly positioned between an outlet port and an inlet port, wherein the regulator valve assembly includes a press button actuator and regulator adjustment dial. A flow control system is secured to the compressed gas unit and the medical grade gas is delivered in precisely controlled amounts by actuating the compressed gas unit and operating the flow control system to deliver the medical grade gas to vasculature of the patient.

A vial adapter assembly that includes a housing, a first receptacle formed within the housing and configured to receive a first vial within the housing, and a second receptacle formed within the housing and configured to receive a second vial within the housing. An opening of the first receptacle and an opening of the second receptacle is in fluid communication with the upper surface of the housing. The vial adapter assembly includes a cap that is coupled and movable relative to the housing from a closed configuration to an open configuration. In the closed configuration, the cap is configured to cover the opening of the first receptacle and the opening of the second receptacle on the upper surface. In the open configuration, the cap is configured to uncover the opening of the first receptacle and the opening of the second receptacle, and expose the upper surface.

A connector for forming a fluid flow pathway by connection with a reciprocal connector. Both the connector and reciprocal connector include a fluid flow blockage partsheathed within an axially compressible sheath part. A first bearing surface receives an urging force to retract the blockage part axially along the sheath part. A terminal end of the sheath part defines a second bearing surface containing a fluid flow opening with the fluid flow blockage part retractably therein. A first chassis part includes a first catch part. A second chassis part includes a second catch part and a third bearing surface spaced from the second catch part along the second chassis part. Retraction of the blockage part forms a fluid flow pathway not sooner than immediately when the openings meet to allow fluid transfer the openings avoiding fluid leakage between connected connectors.

A method for performing a medical procedure requiring effective, reliable and foolproof delivery of controlled amounts of a medical grade gas to a patient includes providing a compressed gas cylinder having a weight with medical grade gas sealed therein of at least twelve grams and not greater than fifty grams. The method also includes connecting the compressed gas cylinder to an integrated compressed gas unit including a regulator valve assembly positioned between an outlet port and an inlet port, wherein the regulator valve assembly includes a press button actuator and regulator adjustment dial. A flow control system is secured to the compressed gas unit and the medical grade gas is delivered in precisely controlled amounts by actuating the compressed gas unit and operating the flow control system to deliver the medical grade gas to vasculature of the patient.

The invention relates to a packaging in the form of an infusion bag, having a connector for a vial, said connector having a spike for piercing the septum of the vial to establish a fluid connection to the inner volume of the infusion bag. The spike is designed to be rotatable. When the vial is rotated, the spike is rotated and the fluid connection between the vial and the inner volume of the infusion bag is opened.