A kit preparation that enables drug dose adjustment. The kit preparation includes a bag which contains an infusion solution or pure water and at least one drug enclosing part in which a drug is enclosed and which is provided with a sealing part. The drug enclosing part is connected to the bag via the sealing part; and, when the sealing part is released, the bag is communicated with the drug enclosing part and thus the drug is poured into the bag so that a dispensing work can be carried out.

A system for the preparation and dispensing of a mixture comprising: i) a container (2) for a first substance; ii) a closure cap (4) of the container (2); iii) a capsule (3) applied to a mouth (20) of the container (2) and comprising: —a containment chamber (31) for the second substance; —a perforation means (32) for perforating the chamber (31) and the cap (4); said system (1) taking on a rest configuration wherein the inside of the container (2) and the inside of the containment chamber (31) are fluid-dynamically separated and an operating configuration wherein said perforation means (32) extends into the chamber (31) and passes through the cap (4); iv) a mixture withdrawal mouth (5) which is part of said container (2) or of said capsule (3); said withdrawal mouth (5) being intended to dispense the mixture of the first and second substances outside the system. The cap (4) may or may not be part of the capsule (3). A movement of said chamber (31) brings about the passage from the rest configuration to the operating configuration; said perforation means (32) comprising a conduit (320) which in said operating configuration places the inside of the container (2) in communication with the inside of the chamber (31). The withdrawal mouth (5) in the rest configuration, is in fluid communication with the chamber (31) or the container (2).

A device for training users in a proper mixing of pharmaceutical components, or for aiding in the mixing, or for performing the mixing, and administration of pharmaceutical components is disclosed. The device comprises a housing for receiving a pharmaceutical delivery device containing the pharmaceutical components. There is also a microcontroller disposed in the housing and a motion/orientation detection device disposed within or on the housing and in communication with the microcontroller. A method for use of the device is also disclosed, along with a substance for use as one of the pharmaceutical components.

A transfer device for transferring a medical fluid from a vial to a medical fluid injection device includes a vial holder where a vial spike positioned within the vial holder is configured to enter a vial containing a medical fluid when the vial is inserted into the vial holder. An expansion chamber having an interior cavity is in fluid communication with the vial spike. A pressurized gas cartridge is positioned with the interior cavity of the expansion chamber, while a puncture tip is configured to puncture the pressurized gas cartridge when actuated by a user. The vial spike is also configured to be in fluid communication with an injection device attached to the transfer device.

An apparatus for transferring a liquid between a storage container and at least one further use container has a storage-container sealing portion for leaktight abutment of a main body of the transfer apparatus against the storage container. A hollow-needle assembly has a hollow needle. The hollow-needle assembly can be displaced in a linear manner along a movement axis relative to the main body by means of a gear mechanism between a retracted rest position and an extended connecting position. In the latter, the hollow needle creates a liquid connecting duct between the storage container and the transfer apparatus. A connecting portion serves to connect the transfer apparatus to the use container in a leaktight manner. A rotary-actuation element is operatively connected to the hollow-needle assembly via the gear mechanism. The gear mechanism has a driver ring that is mounted in the main body axially and so as to be rotatable about the movement axis. Said driver ring interacts with a complementary thread of the hollow-needle assembly for the displacement thereof. The driver ring is connected to the rotary-actuation element for conjoint rotation during the displacement. This results in a transfer apparatus having improved operational reliability, in particular when used by inexperienced patients.

A device for administering an active principle via the oral mucous membrane, having an ampule (1) containing liquid, the ampule including an opening defining a peripheral axial edge (11) closed by a film (10); a syringe barrel (2) with a dispenser orifice; a piston (3) in the syringe barrel (2); a piston rod (4); and a connector (20) formed integrally with or fastened to the syringe barrel (2) and adapted to be connected in leaktight manner to the ampule. The connector includes a perforator (23) for perforating the film and connecting the inside of the ampule with the syringe barrel, the perforator forming the dispenser orifice while the active principle is dispensed. The connector includes an outer protective skirt (21) for creating a gum/cheek cavity while the liquid is deposited and includes an annular reception space (24) for receiving the peripheral axial edge of the ampule.

A system for injecting includes a syringe body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the syringe body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is retractable into plunger interior upon manipulation of the plunger member to actuate the energy-storage member latching member.

Improved apparatus for use with medication in fluid form, which is particularly beneficial for medications having a relatively high viscosity. The disclosed syringe adapter has an opening that is relatively large, as compared to a conventional needle, and thus affixing the disclosed syringe adapter to a syringe improves syringeability of higher-viscosity medications. Some embodiments feature a lateral extension that prevents inserting the syringe adapter too far into a medicine bottle, and some embodiments feature a component that assists in firmly grasping. When the disclosed syringe adapter is affixed to a pistol-grip or tab-handled syringe, the medication withdrawn into the pistol-grip syringe can be more easily administered from the syringe barrel. In some embodiments, the syringe adapter will be replaced with a needle prior to injecting the medication, while in some other embodiments, the needle is affixed to the in-place syringe adapter for the injection. In yet other embodiments, the needle is affixed to a needle holder that, in turn, is affixed to the in-place syringe adapter for the injection.

A method of powderizing a dry cake pharmaceutical drug product for injection within a vial may include securing a vial containing a dry cake pharmaceutical drug product for injection to a shaker device and powderizing the dry cake pharmaceutical drug product within the vial by shaking the vial with the shaker device operated at between about 100 to about 5000 cycles per minute for between about 10 minutes and about 1 hour.

Systems, methods and devices for administering medication are disclosed. One or more embodiments of a medication delivery device may include a syringe, a needle, a guiding element, and a volume limiter for limiting the amount of medication that can be drawn from a vial. At least one method for administering medication using a medication delivery device, may include: inserting a vial into a guiding element, drawing back on a plunger, removing the guiding element and the vial from a needle to expose the needle, inserting the needle into a patient, depressing the plunger to inject the medication into the patient, and withdrawing the medication delivery device from the patient.