The present invention provides a black plaster producing device that comprises a workbench, longitudinal supports, a transverse bottom plate, an electric-heated thermostatic drying oven, and a storage rack structure for classified storage, a storage bucket, a stove, a boiling furnace, a furnace cover, a stirring box, a box cover, a stirring motor, a stirring pipe, a crushing blade, an adjustable partition frame structure, a rolling frame structure, a gas inlet pipe, a pipe valve, a stirring switch, a rolling switch and a receiving bucket, wherein the longitudinal supports are welded at four corners at the lower part of the workbench respectively, and the transverse bottom plate is screwed at the lower part of the longitudinal supports on the inner side. The transverse partition plate of the present invention is screwed at the central position inside the storage box, which facilitates the convenient storage of materials in the storage box during use and can classify the stored materials at the same time. The semiconductor refrigerating chip is screwed on the rear side of the inner wall at the lower part of the storage box, which facilitates the refrigeration and preservation of the materials stored at the bottom of the storage box on the inner side during use.

The present invention provides a black plaster producing device that comprises a workbench, longitudinal supports, a transverse bottom plate, an electric-heated thermostatic drying oven, and a storage rack structure for classified storage, a storage bucket, a stove, a boiling furnace, a furnace cover, a stirring box, a box cover, a stirring motor, a stirring pipe, a crushing blade, an adjustable partition frame structure, a rolling frame structure, a gas inlet pipe, a pipe valve, a stirring switch, a rolling switch and a receiving bucket, wherein the longitudinal supports are welded at four corners at the lower part of the workbench respectively, and the transverse bottom plate is screwed at the lower part of the longitudinal supports on the inner side. The transverse partition plate of the present invention is screwed at the central position inside the storage box, which facilitates the convenient storage of materials in the storage box during use and can classify the stored materials at the same time. The semiconductor refrigerating chip is screwed on the rear side of the inner wall at the lower part of the storage box, which facilitates the refrigeration and preservation of the materials stored at the bottom of the storage box on the inner side during use.

The present disclosure provides peptides and peptide compositions, optionally in the from of a vaccine, which facilitate the delivery of an active agent or an active agent carrier wherein the compositions are capable of penetrating the stratum corneum (SC) and/or the cellular membranes of viable cells. Also provided are methods of employing the peptides and peptide compositions to deliver active agents; treat diseases or disorders; and inducing immune responses.

A topical applicator of the propel/repel type includes a reservoir, an attachable applicator cap, and a metered dosing system. The reservoir is suitable for mixing a topical formulation of multiple constituents using an electronic mortar and pestle and is closed using the applicator cap. Alternatively, the reservoir may be prefilled with a ready-to-use cream and medicament formulation, then sealed with a removable seal. The topical applicator can include a fast purge feature that overrides the metered dosing system to facilitate removal of air from the reservoir. The topical applicator can also include a one-way ratcheting feature to prevent reverse movement (repel) of the metered dosing system. Metered doses can be dispensed through holes in the applicator cap by rotating a knob, which has detent positions that correspond to discrete doses, and which provides audible and tactile feedback.

A dispensing container and adapter system for use with a planetary mixer is disclosed. The dispensing container has a longitudinal axis and a transverse axis. The dispensing container may include a nozzle and a removable cap to cover the nozzle. The removable cap may have a first width dimension measured along the transverse axis. The dispensing container may include a body having a second width dimension measured along the transverse axis. An adapter may receive the dispensing container. The adapter may include a cavity to receive the removable cap. The cavity may have a cavity width that exceeds the first width dimension. The adapter may also include a recess for receiving a portion of the dispensing container. The recess may extend from the cavity. At least a portion of the recess may have a width dimension smaller than both the first width dimension and the second width dimension.

A dispensing container and adapter system for use with a planetary mixer is disclosed. The dispensing container has a longitudinal axis and a transverse axis. The dispensing container may include a nozzle and a removable cap to cover the nozzle. The removable cap may have a first width dimension measured along the transverse axis. The dispensing container may include a body having a second width dimension measured along the transverse axis. An adapter may receive the dispensing container. The adapter may include a cavity to receive the removable cap. The cavity may have a cavity width that exceeds the first width dimension. The adapter may also include a recess for receiving a portion of the dispensing container. The recess may extend from the cavity. At least a portion of the recess may have a width dimension smaller than both the first width dimension and the second width dimension.

A topical applicator of the propel/repel type includes a reservoir, an attachable applicator cap, and a metered dosing system. The reservoir is suitable for mixing a topical formulation of multiple constituents using an electronic mortar and pestle and is closed using the applicator cap. Alternatively, the reservoir may be prefilled with a ready-to-use cream and medicament formulation, then sealed with a removable seal. The topical applicator can include a fast purge feature that overrides the metered dosing system to facilitate removal of air from the reservoir. The topical applicator can also include a one-way ratcheting feature to prevent reverse movement (repel) of the metered dosing system. Metered doses can be dispensed through holes in the applicator cap by rotating a knob, which has detent positions that correspond to discrete doses, and which provides audible and tactile feedback.

The present disclosure relates to a combination including an outer container for mounting in a container holder of a planetary mixer, the outer container receiving an inner container arrangement allowing to mix ingredients into the inner container arrangement with the planetary mixer to produce in the inner container arrangement a pharmaceutical composition. The outer container may include a body having an outer wall and an inner wall. The inner wall may delimit a central cavity for nestably receiving the inner container arrangement. The outer container may also include a slot on the inner wall. The slot may engage with a protrusion on the inner container arrangement when the inner container arrangement is received in the central cavity to inhibit rotational motion of the inner container arrangement within the outer container, induced as a result of combined rotation and revolution imparted to the outer container by the planetary mixer.

The present disclosure relates to a combination including an outer container for mounting in a container holder of a planetary mixer, the outer container receiving an inner container arrangement allowing to mix ingredients into the inner container arrangement with the planetary mixer to produce in the inner container arrangement a pharmaceutical composition. The outer container may include a body having an outer wall and an inner wall. The inner wall may delimit a central cavity for nestably receiving the inner container arrangement. The outer container may also include a slot on the inner wall. The slot may engage with a protrusion on the inner container arrangement when the inner container arrangement is received in the central cavity to inhibit rotational motion of the inner container arrangement within the outer container, induced as a result of combined rotation and revolution imparted to the outer container by the planetary mixer.

The present disclosure relates to a system and process for manufacturing patient personalized pharmaceutical compositions using superimposed revolution and rotation movements for dispersing, milling, melting, and/or de-aerating, where these superimposed revolution and rotation movements can be carried out in a single device in a pharmacy setting.