Patent classifications
A61K2236/13
COMPOUND PREPARATION FOR NEURANAGENESIS, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Disclosed are a compound preparation for neuranagenesis, and a preparation method therefor and the use thereof. The compound preparation for neuranagenesis comprises the raw medicinal materials in parts by weight: 10-20 parts of raw Astragali radix, 10-20 parts of Rehmaimiae Radix praeparata, 10-20 parts of Actyranthes bidentata, 6-15 parts of Jujubae fructus, 6-15 parts of Lycii fructus, 6-15 parts of parched Ziziphi spinosae semen, 6-12 parts of Angelicae smensis radix, 3-9 parts of Carthami flos, 6-15 parts of Poria, 6-15 parts of parched Atractylodis macrocephalae rhizoma and 10-20 parts of Zaocys. The compound preparation can be used for preparing drugs to treat nerve damage diseases, and can be prepared into oral liquids, granules, dissolved granules and tablets.
COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING PULMONARY HYPERTENSION
The present invention provides a method of treating and/or preventing pulmonary hypertension in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a bioactive peptide preparation derived from at least one botanical source.
Arginine-rich Peptide Mixture, their Application Thereof in Cervical Cancer Therapy, and a Process for Producing same
A process for producing an arginine-rich peptide mixture and the application thereof in cervical cancer therapy is provided. The process includes the following steps: A suspension of walnut meal and egg albumin is pretreated with ultrahigh pressure, and then digested by alkaline proteinase and papain in separated steps with the ultrasonic and microwave-assisted extraction. The peptides of interest are isolated from filtration supernatant obtained after the enzyme digestion by reversed phase high-performance liquid chromatography. By using the peptide mixture as a template, acrylic acid and methyl acrylic acid as functional monomers, triethylene glycol dimethacrylate as cross-linking agent, and isopropylthioxanthone in acetone as a photoinitiator, polymerization is induced by ultraviolet light to form a surface imprinted membrane for isolating and enriching the peptides of interest from the supernatant. The arginine content in the peptide mixture is more than 18%. The arginine-rich peptide mixture is able to strongly suppress the proliferation of human cervical cancer Hela cells. The approach is applicable to reduce the cost of production and speed up the commercialization of large-scale production.
PROCESS TO ENHANCE THE BIOACTIVITY OF ASHWAGANDHA EXTRACTS
The invention relates to an extract of Ashwagandha that exhibit enhanced bioactivity and bioavailability comprising of enriched withanolide glycosides and saponins; with negligible amount of alkaloids, withanolide aglycones and oligosaccharides. The extract as disclosed prepared from root, stems, leaves and whole plant of Ashwagandha further shows improved immunomodulatory activity, anti-inflammatory activity, anti stress activity, antidiabetic activity and sleep quality. The disclosure also provides a method of improving bioactivity of withanolide glycosides even at lower doses, by the administration of an enteric coated formulation of extract of Ashwagandha to humans. The enteric coating protects the composition from hydrolysis in the acidic environment of the stomach to release the withanolide glycoside in neutral/ alkaline pH in gastrointestinal tract (GIT) thus enhancing the absorption. Further the process of preparation of the extract of Ashwagandha enriched with withanolide glycosides and saponins are disclosed along with various formulations.
Method for separating eight components in Chinese traditional medicine composition
The solution provides a method for separating a Chinese traditional medicine composition. To explain a pharmacological effect mechanism of a medicine made of two or more components and scientific content in rules of compatibility among components of a compound medicine, systematic researches on the material basis is very necessary. Accordingly, deep researches are done on chemical components of the pharmaceutical composition in the solution, and eight compounds are separated, which are 10-O-(p-hydroxycinnamoyl)-adoxosidic acid, aloe-emodin-8-O-β-D-glucopyranoside, quercitrin, matairesinol-4′-O-glucoside, liquiritin apioside, epi-vogeloside, vogeloside and ethyl caffeate, which provides a new quality control method for the composition in the solution.
Alvoecore a Respiratory System Protection Product and Immune System Booster
The present invention is a respiratory system protection product and a method for creating said product. The product is created by separating an aloe vera gel from a quantity of aloe vera leaves. The aloe vera gel is added to a heating vessel. A first solution is prepared and added to cover the aloe vera gel. The heating vessel is covered, heated, and stirred until boiling, then removed from heat. After cooling to room temperature an oil component is added. The mixture is blended and amalgamated, then filtered to remove solid materials.
Curcumin nanoparticle and preparation and application thereof
Disclosed is a curcumin nanoparticle, including curcumin as core material and a wall material, where a weight ratio of the curcumin to the wall material is (5.5-7.5):100, and the wall material includes gum arabic and zein in a weight ratio of (1-5):5. The disclosure further provides a method of making the curcumin nanoparticle and a curcumin beverage containing the curcumin nanoparticle.
COMPOSITION FOR ELIMINATING HOUSEHOLD PET ALLERGENS
The present invention discloses a preparation method and application of anti-cat-and-dog allergen finishing composition solution. The preparation process is as follows: Japanese Diospyros rhombifolia Hemsl and Canangaodorata petals were washed for 3˜5 times, ground and ultrasonically treated to prepare suspension liquid; the suspension liquid was treated by microwave and then centrifuged to obtain light yellow supernate; the light yellow supernate was performed with membrane separation treatment to form a mixed extract of Japanese Diospyros rhombifolia Hemsl and Canangaodorata; the obtained mixed extract of Japanese Diospyros rhombifolia Hemsl and Canangaodorata was mixed with silver ion compound, Eucalyptus oil, fatty alcohol polyoxyethylene ether, sodium dodecyl benzene sulfonate, sodium laurate, sodium stearate, citric acid, serine protease, pectinase, cellulase, xylanase, beta-glucanase, glycerol, cetyldimethyl benzyl ammonium chloride, chitosan, pigment, plant essence, preservative and deionized water evenly, according to a certain mass share ratio; ultrasonically vibrating the mixture at a certain temperature for a certain time, and cooling the mixture to room temperature to obtain the anti-cat-and-dog allergen finishing composition solution. The preparation method of the composition is simple, and can be used for daily spraying and wiping, and can also be used in the washing or drying process of clothes.
HIGHLY RESISTANT STARCH AND MANUFACTURING PROCESS THEREFOR
The present disclosure relates to highly resistant starch compositions, methods for preparing such highly resistant starch compositions, and methods of using such highly resistant starch compositions to treat or prevent a disease or condition associated with dysregulation and/or dysfunction of the intestinal microbiome.
THE USE OF UNRIPENED GREEN MANGIFERA INDICA AS A NATURAL PREPARATION TO TREAT SARS-COV-2
The present disclosure provides a method for an effective decoction preparation of unripe green Mangifera indica to treat and prevent anti-SARS-CoV-2. The disclosure extends to uses of such preparation as medicaments and to methods of treating anti-SARS-CoV-2 infections, and tolerating the vaccine side-effects. The disclosure further extends to methods for preventing anti-SARS-CoV-2 infections by coating objects and surfaces with the compositions.