Provided are liquid and powder grape extracts having elevated phenolic content. The extracts can be made from grape seeds, grape skins, or a combination thereof. In some instances, extracts may be blends of grape seed extracts and grape skin extracts. Methods of manufacturing such extracts area also provided. Such methods involve controlled temperature conditions to increase yield of phenolic compounds in the extracts. Methods of using the extraction for treating subjects are also provided, including treatment of cancer and end-organ damage relating to hypertension.

A traditional Chinese medicine composition, made from cassia twig, poria, Cortex moutan, Radix paeoniae alba, peach kernel in equal proportions. The traditional Chinese medicine composition comprises paeoniflorin, amygdalin, benzoylpaeoniflorin, cinnamic acid, paeonol, and cinnamaldehyde. The composition has the advantages of high production efficiency, high content of effective ingredients, high transfer rate of poria acid, reduced hygroscopicity, and improved dissolution of index ingredients.

A Fructus Forsythiae and Radix Astragali compound preparation, and a preparation method therefor and a use thereof is provided. Traditional Chinese medicine formulation components consist of the following raw materials or raw material extracts in parts by mass: 9-11 parts of Flos Lonicerae, 9-11 parts of Fructus Forsythiae, 9-11 parts of Radix Scutellariae, 9-11 parts of Herba Artemisiae Annuae, 9-11 parts of Radix Astragali, 9-11 parts of stir-fried Rhizoma Atractylodis Macrocephalae, 9-11 parts of Herba Pogostemonis, 5-7 parts of Radix Saposhnikoviae, 9-11 parts of Radix Ophiopogonis, and 5-7 parts of Radix Glycyrrhizae. The components can be made into an oral liquid, a granule, a dissolved medicine, or a tablet. Further disclosed is a use of the Fructus Forsythiae and Radix Astragali compound preparation in preparation of medicines for preventing and/or treating a viral influenza disease.

Disclosed are a compound preparation for neuranagenesis, and a preparation method therefor and the use thereof. The compound preparation for neuranagenesis comprises the raw medicinal materials in parts by weight: 10-20 parts of raw Astragali radix, 10-20 parts of Rehmaimiae Radix praeparata, 10-20 parts of Actyranthes bidentata, 6-15 parts of Jujubae fructus, 6-15 parts of Lycii fructus, 6-15 parts of parched Ziziphi spinosae semen, 6-12 parts of Angelicae smensis radix, 3-9 parts of Carthami flos, 6-15 parts of Poria, 6-15 parts of parched Atractylodis macrocephalae rhizoma and 10-20 parts of Zaocys. The compound preparation can be used for preparing drugs to treat nerve damage diseases, and can be prepared into oral liquids, granules, dissolved granules and tablets.

[Problem] To provide a novel medicine that is capable of promoting cholesterol metabolism to thereby treat, ameliorate or prevent various symptoms associated with increase in blood cholesterol level. [Solution] The present inventors newly found that arctigenin has an effect of promoting the conversion of cholesterol into bile acid. The present invention provides a bile acid synthesis promoter, a composition for promoting bile acid synthesis and a food composition for promoting bile acid synthesis each comprising arctigenin and/or arctiin as active ingredient(s).

A pharmaceutical composition, dietary supplement, or food containing a Perilla frutescens fermented extract is disclosed. The composition is useful for prevention or treatment of a sleep disorder. A composition or a fiber or fragrance composition containing a Perilla frutescens fermented extract is also disclosed. A method for treating sleep disorder employing the pharmaceutical composition, dietary supplement, food, or the fiber or fragrance composition is disclosed.

Provided are: a method of preparing a cannabis processed product having an increased CBD content in an efficient and economic manner, through a decarboxylation reaction by continuous microwave irradiation of a cannabis extract; and use of a processed product having an increased CBD content prepared by the method, a fraction thereof, and a single ingredient of CBD, in foods, drugs, and cosmetics.

This invention relates to a method of treating Major depressive disorder by orally administering to a subject a composition containing a Radix Polygalae (Polygala tenuifolia Willd) extract (PDC-1421). A solid dosage form of PDC-1421 can be prepared into the gelatin capsule. The oral administration of PDC-1421 in healthy volunteers was safe and well-tolerated for the daily dose from 380 mg to 3800 mg. The composition can be administered chronically over at least 25 days; the daily dose is administered once per day, twice per day, or three times per day, wherein each dose is 380-760 mg of the botanical extraction.

A vitamin D2-enriched biomass of an edible fungus, extracts and compositions thereof are provided, for use in delaying onset of, treating, ameliorating or protecting from an immune-related or inflammatory related disease, disorder or condition, wherein the level of vitamin D2 in said biomass is at least 80 IU/gr.

The present invention refers to the use of an extract from chestnut shells (CSE), peeling waste of the chestnut, (fruit of the tree Castanea sativa Mill., European Chestnut), or fractions of said extract, with specific antiviral activity in the treatment and/or prevention of Herpesviridae, Retroviridae, and Coronaviridae infections.