The present invention relates to a two-component cosmetic composition for wrinkle reduction. The two-component cosmetic composition for wrinkle reduction according to the present invention forms a coating having a sufficient strength to reduce a scrubbing phenomenon caused by external force and has a suitable viscosity as well as no cloudiness phenomena arising.

The present invention relates to a structure for accelerating transdermal absorption, a manufacturing method thereof, and a cosmetic composition comprising the same, and the structure for accelerating transdermal absorption comprises an acicular body; a hydrophilic group binded to the acicular body; and a carrier binded to the hydrophilic group.

Surface-modified zinc oxide particles which have a silane coupling agent having an alkoxy group on surfaces thereof, in which d50 when measured with a laser diffraction/scattering type particle size distribution-measuring instrument by the following measurement method is 4 μm or less. (Measurement method) 10 g of the surface-modified zinc oxide particles, 88 g of cyclopentasiloxane, and 2 g of polyglyceryl-3 polydimethylsiloxyethyl dimethicone are mixed to obtain a liquid mixture, a dispersion treatment is performed on the obtained liquid mixture at 9,500 rpm for 5 minutes using a homogenizer to obtain a liquid dispersion, the liquid dispersion is diluted with cyclopentasiloxane so that a content of the surface-modified zinc oxide particles in the obtained liquid dispersion is 0.01% by mass to produce a measurement solution, and d50 is measured with the laser diffraction/scattering type particle size distribution-measuring instrument using the obtained measurement solution.

Photochromic formulations including a core material and a photochromic layer overlying the core material and forming a particle are provided. The photochromic layer may include a plurality of photochromic materials, including a first photo-responsive pigment characterized by reversible diffuse reflectance at a first central wavelength from 490 nm to 520 nm in response to irradiation by photons of a first characteristic wavelength, a second photo-responsive pigment characterized by reversible diffuse reflectance at a second central wavelength from 570 nm to 590 nm in response to irradiation by photons of a second characteristic wavelength, and a third photo-responsive pigment characterized by reversible diffuse reflectance at a third central wavelength from 450 nm to 495 nm and a fourth central wavelength from 625 nm to 740 nm in response to irradiation by photons of a third characteristic wavelength. The first, second, and third characteristic wavelengths may be different.

A low-viscosity water-in-oil cosmetic emulsion preparation gives a smooth use feeling, lightly spreads when applied, and has excellent dispersed-powder stability. The cosmetic emulsion preparation has (A) a polar oil which is liquid at 25° C. and has an IOB value exceeding 0.1, (B) a hydrocarbon oil, (C) a polyoxyalkylene; and alkyl-modified organopolysiloxane represented by general formula (I), and (D) a powder surface-treated with both an N-acylamino acid and methylpolysiloxane. (In formula (I), R represents a hydrogen atom or a C1-5 alkyl group, x is an integer of 5-50, y is an integer of 1-30, z is an integer of 20-200, a is an integer of 2-20, b is an integer of 1-5, c is an integer of 2-20, and d is an integer of 0-20). ##STR00001##

The present application is related to cancer immunotherapy, e.g. stimulation of T cell mediated anti-tumor therapy. Accordingly, described herein are methods of inducing or enhancing an adaptive immune response to a cancer in a subject and methods of treating cancer in a subject. In some embodiments, the methods hyperactivate dendritic cells (DCs), which induce T helper type I (TH1) and cytotoxic T lymphocyte (CTL) responses in the absence of TH2 immunity.

Disclosed is a composite for forming a coacervate interfacial film. The composite for forming the coacervate interfacial film contains a cationic hectorite nanoplate-shaped particle structure containing a hectorite nanoplate-shaped particle and a cationic surfactant coupled to a surface of the hectorite nanoplate-shaped particle, and an anionic cellulose nanofibril containing an anionic functional group in at least a portion thereof, in which the composite may form the coacervate interfacial film at an interface of an oil phase and a water phase through electrostatic interaction between the cationic surfactant and the anionic functional group.

The present disclosure relates to a skin film forming agent, and provides a skin film forming agent which comprises dimethiconol, hydride dimethicone and a cross-linking component, and thereby provides a skin film forming agent which has no problem of safety, and forms a film with high intensity, and thereby can solve peeling and slipping of the film and effectively improve skin disadvantages, particularly, wrinkles and elasticity.

[Problem] To provide a decorating powder composition for decorating the surface of a solid cosmetic material, in particular, for obtaining a solid cosmetic material having a beautiful appearance which is decorated with a glossy powder, and a decorating method using the decorating powder composition. [Solution] Provided are a decorating powder composition including a glossy powder which has been surface-treated with a silane compound or a silazane compound, and a method for decorating a solid cosmetic material, the method including causing the decorating powder composition to adhere to a printing plate and then bringing the printing plate into contact with a surface of the solid cosmetic material to transfer the decorating powder composition to the surface of the solid cosmetic material and decorate the solid cosmetic material.

One aspect of the present disclosure is an organic/inorganic composite powder and a composition including the same in which a coating film on a surface of an inorganic powder is not easily fall off under various conditions such as pH, temperature, physical force, etc., so that has excellent moisture retention and less transferring and allows for natural makeup.