A61K31/22

Wound honey with a pump dispenser
20230046815 · 2023-02-16 ·

An improved wound honey using a combination of buckwheat honey, honeydew honey, a natural thickening agent of blackstrap molasses and tangerine puree, and fragrance comprising lavender essential oil. The wound honey is sterilized using a flowing UV light sanitizing system. The bottles are disinfected using a combination parecetic acid, formic acid, vanillin, clove essential oil, monolaurin, aloe vera, and hydrogen peroxide disinfectant. The product comes in a container with a pump dispenser that dispenses a quantifiable amount of product. This new wound honey with pump dispenser may be used multiple times, is cheaper than manuka honey, and may be produced outside of New Zealand and Australia.

Wound honey with a pump dispenser
20230046815 · 2023-02-16 ·

An improved wound honey using a combination of buckwheat honey, honeydew honey, a natural thickening agent of blackstrap molasses and tangerine puree, and fragrance comprising lavender essential oil. The wound honey is sterilized using a flowing UV light sanitizing system. The bottles are disinfected using a combination parecetic acid, formic acid, vanillin, clove essential oil, monolaurin, aloe vera, and hydrogen peroxide disinfectant. The product comes in a container with a pump dispenser that dispenses a quantifiable amount of product. This new wound honey with pump dispenser may be used multiple times, is cheaper than manuka honey, and may be produced outside of New Zealand and Australia.

PHARMACEUTICAL COMPOSITION COMPRISING TRANS - CINNAMALDEHYDE AND ITS USE IN THE TREATMENT OF INFECTIONS
20230049807 · 2023-02-16 · ·

This invention pertains to an anti-microbial, in particular anti-bacterial, more particularly against Gram negative bacteria, and/or anti-fungal composition comprising as active blend trans-cinnamaldehyde and a potentiating agent. In particular this composition is intended for preventing and/or treating microbial infection in an animal.

PHARMACEUTICAL COMPOSITION COMPRISING TRANS - CINNAMALDEHYDE AND ITS USE IN THE TREATMENT OF INFECTIONS
20230049807 · 2023-02-16 · ·

This invention pertains to an anti-microbial, in particular anti-bacterial, more particularly against Gram negative bacteria, and/or anti-fungal composition comprising as active blend trans-cinnamaldehyde and a potentiating agent. In particular this composition is intended for preventing and/or treating microbial infection in an animal.

PHARMACEUTICAL COMPOSITION COMPRISING TRANS - CINNAMALDEHYDE AND ITS USE IN THE TREATMENT OF INFECTIONS
20230049807 · 2023-02-16 · ·

This invention pertains to an anti-microbial, in particular anti-bacterial, more particularly against Gram negative bacteria, and/or anti-fungal composition comprising as active blend trans-cinnamaldehyde and a potentiating agent. In particular this composition is intended for preventing and/or treating microbial infection in an animal.

COMPOSITIONS AND METHODS FOR TREATING HOT FLASHES

The present disclosure relates to compositions comprising an aqueous solution of at least about 70% by weight water in combination with selected fatty acid salts and optionally an alcohol and/or a cooling sensate, as well as methods of using the same to treat symptoms of hot flashes. The fatty acid salts form fiber-like crystalline particles that together form a self-supporting mesh structure with voids, the aqueous solution being contained in the voids. When the composition is compressed above a critical stress, the mesh allows for the entrapped aqueous solution to be expressed.

COMBINATION THERAPY APPROACH TO ELIMINATE HIV INFECTIONS
20230011398 · 2023-01-12 ·

By a Selective Elimination of Host Cells Capable of Producing HIV (SECH) approach, which includes a combination of latency reversal, blocking of new infections, inhibition of autophagy and induction of apoptosis, host cells harboring productive HIV infections can be cleared from a subject. Disclosed herein are methods for treating or inhibiting HIV in a subject, comprising a) reactivating latent HIV integrated into the genome of a cell infected with HIV in the subject, b) optionally administering to the subject an effective amount of a therapeutic agent to inhibit HIV infection, and c) administering to the subject an effective amount of a therapeutic agent to eliminate or reduce the number of cells containing replication-competent HIV. Kits for treating or inhibiting HIV in a subject are also disclosed.

COMBINATION THERAPY APPROACH TO ELIMINATE HIV INFECTIONS
20230011398 · 2023-01-12 ·

By a Selective Elimination of Host Cells Capable of Producing HIV (SECH) approach, which includes a combination of latency reversal, blocking of new infections, inhibition of autophagy and induction of apoptosis, host cells harboring productive HIV infections can be cleared from a subject. Disclosed herein are methods for treating or inhibiting HIV in a subject, comprising a) reactivating latent HIV integrated into the genome of a cell infected with HIV in the subject, b) optionally administering to the subject an effective amount of a therapeutic agent to inhibit HIV infection, and c) administering to the subject an effective amount of a therapeutic agent to eliminate or reduce the number of cells containing replication-competent HIV. Kits for treating or inhibiting HIV in a subject are also disclosed.

COMPOSITIONS AND METHODS FOR TREATMENT OF PLATINUM-BASED CHEMOTHERAPEUTIC RESISTANT TUMORS
20230012172 · 2023-01-12 ·

Embodiments of the instant disclosure relate to novel methods and compositions for treating tumors resistant to platinum-based chemotherapy. In certain embodiments, methods of treating tumors herein can include administering an effective amount of at least one ursolic acid derivative. In certain embodiments, methods of treating tumors herein can include administering an effective amount of at least one ursolic acid derivative in combination with at least one platinum-based chemotherapeutic separately or in a combination therapy. In some embodiments, methods of treating tumors disclosed herein can include screening and/or selecting a subject suitable for treatment on the basis of SENP1 tumor expression. In other embodiments, methods of treating tumors can include administering a composition disclosed herein to a subject, the composition having a combination of at least one ursolic acid derivative and at least one platinum-based chemotherapeutic.

COMPOSITIONS AND METHODS FOR TREATMENT OF PLATINUM-BASED CHEMOTHERAPEUTIC RESISTANT TUMORS
20230012172 · 2023-01-12 ·

Embodiments of the instant disclosure relate to novel methods and compositions for treating tumors resistant to platinum-based chemotherapy. In certain embodiments, methods of treating tumors herein can include administering an effective amount of at least one ursolic acid derivative. In certain embodiments, methods of treating tumors herein can include administering an effective amount of at least one ursolic acid derivative in combination with at least one platinum-based chemotherapeutic separately or in a combination therapy. In some embodiments, methods of treating tumors disclosed herein can include screening and/or selecting a subject suitable for treatment on the basis of SENP1 tumor expression. In other embodiments, methods of treating tumors can include administering a composition disclosed herein to a subject, the composition having a combination of at least one ursolic acid derivative and at least one platinum-based chemotherapeutic.