Methods of forming a gel and related methods of treating subjects with such gels are described. The method may include preparing a composition by combining a macromer comprising a first polyethylene glycol (PEG)-based polymer, a poly(ethylenimine)-based polymer, or a poly(1,2-glycerol) carbonate-based polymer, the macromer including at least one first functional moiety, a crosslinking agent comprising a second PEG-based polymer that includes at least one second functional moiety, and a photoinitiator, and activating the photoinitiator via a light source to form the gel.

Methods of forming a gel and related methods of treating subjects with such gels are described. The method may include preparing a composition by combining a macromer comprising a first polyethylene glycol (PEG)-based polymer, a poly(ethylenimine)-based polymer, or a poly(1,2-glycerol) carbonate-based polymer, the macromer including at least one first functional moiety, a crosslinking agent comprising a second PEG-based polymer that includes at least one second functional moiety, and a photoinitiator, and activating the photoinitiator via a light source to form the gel.

A method of enhancing penetration of a topical composition of 5-aminolevulinic acid (ALA) into tissue for photodynamic therapy includes topically applying ALA to a treatment area to be treated with photodynamic therapy. The method further includes, after the ALA is applied to the treatment area, covering the treatment area with a low density polyethylene barrier. The treatment area is covered with the low density polyethylene barrier prior to light treatment to minimize transepidermal water loss from the treatment area.

A method of enhancing penetration of a topical composition of 5-aminolevulinic acid (ALA) into tissue for photodynamic therapy includes topically applying ALA to a treatment area to be treated with photodynamic therapy. The method further includes, after the ALA is applied to the treatment area, covering the treatment area with a low density polyethylene barrier. The treatment area is covered with the low density polyethylene barrier prior to light treatment to minimize transepidermal water loss from the treatment area.

The invention relates to a new combination of hyaluronic acid and macrogol, pharmaceutical compositions containing said combination and the use of the combination and compositions as laxatives.

The invention relates to a new combination of hyaluronic acid and macrogol, pharmaceutical compositions containing said combination and the use of the combination and compositions as laxatives.

A mixture for enhancing eye lubrication comprises a plurality of microspheres having diameters ranging from about 5-40 microns combined with an aqueous component comprising water. The microspheres can be coated with oil. When the mixture is applied to the surface of a user's eyes, the microparticles will enhance lubrication during blinking and partially lift eyelids so that other components of the mixture can be better distributed beneath the eyelids. An oil can be added to the mixture. Preferably the oil is configured so that, when the mixture is agitated, it forms a temporary, thermodynamically unstable emulsion from which the oil quickly disassociates when the mixture is applied to the eye. The oil thus is quickly available to enhance lubrication performance.

A mixture for enhancing eye lubrication comprises a plurality of microspheres having diameters ranging from about 5-40 microns combined with an aqueous component comprising water. The microspheres can be coated with oil. When the mixture is applied to the surface of a user's eyes, the microparticles will enhance lubrication during blinking and partially lift eyelids so that other components of the mixture can be better distributed beneath the eyelids. An oil can be added to the mixture. Preferably the oil is configured so that, when the mixture is agitated, it forms a temporary, thermodynamically unstable emulsion from which the oil quickly disassociates when the mixture is applied to the eye. The oil thus is quickly available to enhance lubrication performance.

A method of enhancing penetration of a topical composition of 5-aminolevulinic acid (ALA) into tissue for photodynamic therapy includes topically applying ALA to a treatment area to be treated with photodynamic therapy. The method further includes, after the ALA is applied to the treatment area, covering the treatment area with a low density polyethylene barrier. The treatment area is covered with the low density polyethylene barrier prior to light treatment to minimize transepidermal water loss from the treatment area.

A method of enhancing penetration of a topical composition of 5-aminolevulinic acid (ALA) into tissue for photodynamic therapy includes topically applying ALA to a treatment area to be treated with photodynamic therapy. The method further includes, after the ALA is applied to the treatment area, covering the treatment area with a low density polyethylene barrier. The treatment area is covered with the low density polyethylene barrier prior to light treatment to minimize transepidermal water loss from the treatment area.