This invention relates to oral care compositions comprising herbal extracts including, e.g., Gymnema sylvestre, Emblica officinalis, Eugenia jambolana, Azadirachta indica, and combinations thereof and zinc salts, e.g., zinc citrate and zinc oxide. Additionally, the invention relates to methods of using and of making these compositions, e.g., method of using the oral care compositions to treat gingivitis in diabetic consumers.

This invention relates to oral care compositions comprising herbal extracts including, e.g., Gymnema sylvestre, Emblica officinalis, Eugenia jambolana, Azadirachta indica, and combinations thereof and zinc salts, e.g., zinc citrate and zinc oxide. Additionally, the invention relates to methods of using and of making these compositions, e.g., method of using the oral care compositions to treat gingivitis in diabetic consumers.

A nutritional supplement composition that enhances the incorporation of calcium and other bone building elements in bone and that prevents bone breakdown, specifically due to the chronic metabolic acidosis that the typical Western diet generates each day. The transcription factor NFKB (Nuclear Factor Kappa B), which underlies some of this physiology, has also been shown to adversely affect fat metabolism. The enzymatic protein complex, AMP Kinase (Adenosine Monophosphate Kinase), a key regulator of energy metabolism, has been shown to reverse the effects of excessive NFKB activity on bone and fat metabolism. The novel nutrients modulate nutrient partitioning and fat metabolism in a human or animal so as to increase oxidation of fat, decrease storage of fat and promote increased storage of glycogen. They are composed of one or more of nutrients selected from the group consisting of Hesperidin, Berberine, Epigallocatechin 3-Gallate (EGCG), Resveratrol, Curcumin, Ginsenosides, Gingerols, Hispidulin, Honokiol, Magnolol and Quercetin. A method for modulating nutrient partitioning in a human involves orally or parenterally administering the aforementioned composition to the human or animal, preferably on a daily basis, for a therapeutically effective period of time. Preferably, the method further involves having the recipient follow a specific dietary regimen wherein the glycemic index is less than 60 and the daily calorie consumption from carbohydrates is less than about 50% and the daily calorie consumption from protein is at least about 20%. Optionally, the method further involves an exercise program, a stress reduction program and/or a blood donation program.

A nutritional supplement composition that enhances the incorporation of calcium and other bone building elements in bone and that prevents bone breakdown, specifically due to the chronic metabolic acidosis that the typical Western diet generates each day. The transcription factor NFKB (Nuclear Factor Kappa B), which underlies some of this physiology, has also been shown to adversely affect fat metabolism. The enzymatic protein complex, AMP Kinase (Adenosine Monophosphate Kinase), a key regulator of energy metabolism, has been shown to reverse the effects of excessive NFKB activity on bone and fat metabolism. The novel nutrients modulate nutrient partitioning and fat metabolism in a human or animal so as to increase oxidation of fat, decrease storage of fat and promote increased storage of glycogen. They are composed of one or more of nutrients selected from the group consisting of Hesperidin, Berberine, Epigallocatechin 3-Gallate (EGCG), Resveratrol, Curcumin, Ginsenosides, Gingerols, Hispidulin, Honokiol, Magnolol and Quercetin. A method for modulating nutrient partitioning in a human involves orally or parenterally administering the aforementioned composition to the human or animal, preferably on a daily basis, for a therapeutically effective period of time. Preferably, the method further involves having the recipient follow a specific dietary regimen wherein the glycemic index is less than 60 and the daily calorie consumption from carbohydrates is less than about 50% and the daily calorie consumption from protein is at least about 20%. Optionally, the method further involves an exercise program, a stress reduction program and/or a blood donation program.

The present invention pertains to: the provision of a method for promoting skin wound healing and a composition to be used for promoting skin wound healing; the provision of a method useful for preventing or ameliorating ulcers and bedsores or a composition therefor; the provision of a method for preventing skin aging and a composition to be used for preventing skin aging; the provision of a composition useful for preventing or ameliorating skin damage caused by an anticancer agent; and, furthermore, the provision of a method for enhancing the regeneration ability of epidermal stem cells and a composition for enhancing the regeneration ability of epidermal stem cells. More specifically, use of a composition, said composition being characterized by comprising, as an active ingredient, a substance selected from the group consisting of a substance which induces or maintains the expression of COL17A1 in cells, a substance which inhibits the degradation of COL17A1 in cells, a substance which promotes the competitive amplification ability of epidermal stem cells, a substance which suppresses genomic stress or oxidative stress in cells and a substance which prevents DNA damage in cells, enables the promotion of skin wound healing, protection from an anticancer agent and prevention of skin aging. Thus, the regeneration ability of epidermal stem cells can be enhanced.

A composition for treating respiratory diseases and strengthening the immune system is provided including a synergic mixture of a) oil extracted from seeds of the plant Nigella sativa diluted in propylene glycol with b) an alcoholic extract with ethanol obtained from aerial parts of the plant Asclepias curassavica. The composition is prepared by (a) extracting seed oil from the Nigella sativa plant, adding the extracted seed oil to propylene glycol; (b) macerating aerial parts of Asclepias curassavica plants in ethanol with a resting time if subjected to a water bath or another resting time without the water bath, straining and filtering; c) mixing a volume of the alcoholic extract of Asclepias curassavica with a volume of oil extracted from the seeds of the Nigella sativa plant diluted in propylene glycol; d) shaking and letting it rest.

A composition for treating respiratory diseases and strengthening the immune system is provided including a synergic mixture of a) oil extracted from seeds of the plant Nigella sativa diluted in propylene glycol with b) an alcoholic extract with ethanol obtained from aerial parts of the plant Asclepias curassavica. The composition is prepared by (a) extracting seed oil from the Nigella sativa plant, adding the extracted seed oil to propylene glycol; (b) macerating aerial parts of Asclepias curassavica plants in ethanol with a resting time if subjected to a water bath or another resting time without the water bath, straining and filtering; c) mixing a volume of the alcoholic extract of Asclepias curassavica with a volume of oil extracted from the seeds of the Nigella sativa plant diluted in propylene glycol; d) shaking and letting it rest.

A composition for treating respiratory diseases and strengthening the immune system is provided including a synergic mixture of a) oil extracted from seeds of the plant Nigella sativa diluted in propylene glycol with b) an alcoholic extract with ethanol obtained from aerial parts of the plant Asclepias curassavica. The composition is prepared by (a) extracting seed oil from the Nigella sativa plant, adding the extracted seed oil to propylene glycol; (b) macerating aerial parts of Asclepias curassavica plants in ethanol with a resting time if subjected to a water bath or another resting time without the water bath, straining and filtering; c) mixing a volume of the alcoholic extract of Asclepias curassavica with a volume of oil extracted from the seeds of the Nigella sativa plant diluted in propylene glycol; d) shaking and letting it rest.

The present invention relates to a composition for improving, preventing or treating an anxiety disorder, and a tranquilizing composition.

The present invention relates to a composition for improving, preventing or treating an anxiety disorder, and a tranquilizing composition.