Patent classifications
A61K36/532
FRUCTUS FORSYTHIAE AND RADIX ASTRAGALI COMPOUND PREPARATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF
A Fructus Forsythiae and Radix Astragali compound preparation, and a preparation method therefor and a use thereof is provided. Traditional Chinese medicine formulation components consist of the following raw materials or raw material extracts in parts by mass: 9-11 parts of Flos Lonicerae, 9-11 parts of Fructus Forsythiae, 9-11 parts of Radix Scutellariae, 9-11 parts of Herba Artemisiae Annuae, 9-11 parts of Radix Astragali, 9-11 parts of stir-fried Rhizoma Atractylodis Macrocephalae, 9-11 parts of Herba Pogostemonis, 5-7 parts of Radix Saposhnikoviae, 9-11 parts of Radix Ophiopogonis, and 5-7 parts of Radix Glycyrrhizae. The components can be made into an oral liquid, a granule, a dissolved medicine, or a tablet. Further disclosed is a use of the Fructus Forsythiae and Radix Astragali compound preparation in preparation of medicines for preventing and/or treating a viral influenza disease.
FRUCTUS FORSYTHIAE AND RADIX ASTRAGALI COMPOUND PREPARATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF
A Fructus Forsythiae and Radix Astragali compound preparation, and a preparation method therefor and a use thereof is provided. Traditional Chinese medicine formulation components consist of the following raw materials or raw material extracts in parts by mass: 9-11 parts of Flos Lonicerae, 9-11 parts of Fructus Forsythiae, 9-11 parts of Radix Scutellariae, 9-11 parts of Herba Artemisiae Annuae, 9-11 parts of Radix Astragali, 9-11 parts of stir-fried Rhizoma Atractylodis Macrocephalae, 9-11 parts of Herba Pogostemonis, 5-7 parts of Radix Saposhnikoviae, 9-11 parts of Radix Ophiopogonis, and 5-7 parts of Radix Glycyrrhizae. The components can be made into an oral liquid, a granule, a dissolved medicine, or a tablet. Further disclosed is a use of the Fructus Forsythiae and Radix Astragali compound preparation in preparation of medicines for preventing and/or treating a viral influenza disease.
COMPOSITION FOR THE PREVENTION OR TREATMENT OF RESPIRATORY DISEASES CAUSED BY FINE DUST COMPRISING AGASTACHE RUGOSA AND LICORICE EXTRACT
The present invention relates to a composition for the prevention or treatment of respiratory diseases containing an Agastacherugosa and licorice extract as an active ingredient, and more specifically, the present invention relates to a composition for the prevention or treatment of respiratory diseases caused by fine dust containing an extract, in which Agastacherugosa and licorice are mixed at a weight ratio of 1:1 to 6:1, as an active ingredient.
The Agastacherugosa and licorice extract of the present invention has the efficacies of reducing cough through inhibition of TRPV1 activity, reducing lung inflammation through inhibition of CXCR1 and CXCR2 activities and GR-1+CD11b+ cell ratio reduction, and suppressing sputum production through inhibition of MUC5AC activity. In particular, since it is confirmed that the efficacy of the Agastacherugosa and licorice complex mixture is maximized at a specific mixing ratio, it can be widely utilized as a composition for the prevention or treatment of respiratory diseases caused by fine dust.
COMPOSITION FOR THE PREVENTION OR TREATMENT OF RESPIRATORY DISEASES CAUSED BY FINE DUST COMPRISING AGASTACHE RUGOSA AND LICORICE EXTRACT
The present invention relates to a composition for the prevention or treatment of respiratory diseases containing an Agastacherugosa and licorice extract as an active ingredient, and more specifically, the present invention relates to a composition for the prevention or treatment of respiratory diseases caused by fine dust containing an extract, in which Agastacherugosa and licorice are mixed at a weight ratio of 1:1 to 6:1, as an active ingredient.
The Agastacherugosa and licorice extract of the present invention has the efficacies of reducing cough through inhibition of TRPV1 activity, reducing lung inflammation through inhibition of CXCR1 and CXCR2 activities and GR-1+CD11b+ cell ratio reduction, and suppressing sputum production through inhibition of MUC5AC activity. In particular, since it is confirmed that the efficacy of the Agastacherugosa and licorice complex mixture is maximized at a specific mixing ratio, it can be widely utilized as a composition for the prevention or treatment of respiratory diseases caused by fine dust.
COMPOSITION FOR STRENGTHENING SKIN BARRIER OR MOISTURIZING SKIN COMPRISING TILIANIN
A composition for strengthening a skin barrier or moisturizing skin is provided. The composition includes tilianin. The composition may be a food, a health functional food composition, a quasi-drug composition and/or a composition for external use on the skin. The composition increases the contents of moisture and hyaluronic acid in the skin and exhibits an upregulating effect on HAS. A method for strengthening a skin barrier or enhancing skin moisture using tilianin, and provides a use of tilianin in the preparation of food or medicine for strengthening a skin barrier or enhancing skin moisture are also provided.
COMPOSITION FOR STRENGTHENING SKIN BARRIER OR MOISTURIZING SKIN COMPRISING TILIANIN
A composition for strengthening a skin barrier or moisturizing skin is provided. The composition includes tilianin. The composition may be a food, a health functional food composition, a quasi-drug composition and/or a composition for external use on the skin. The composition increases the contents of moisture and hyaluronic acid in the skin and exhibits an upregulating effect on HAS. A method for strengthening a skin barrier or enhancing skin moisture using tilianin, and provides a use of tilianin in the preparation of food or medicine for strengthening a skin barrier or enhancing skin moisture are also provided.
COMPOSITION FOR INHIBITING OSTEOCLASTS CONTAINING AGASTACHE RUGOSA EXTRACT AS ACTIVE INGREDIENT, AND USE THEREOF
The Agastache rugosa extract or the isoagastachoside or crude polysaccharide fraction included in the extract according to the present invention can be prepared based on plants being domestically cultivated, and thus is advantageous in terms of time and cost, and can effectively inhibit the differentiation, growth, and bone resorption functions of osteoclast progenitor cells, thus increasing bone density and the like, and accordingly, can be effectively used for the prevention, amelioration, or treatment of diseases related to bone loss caused by differentiation into osteoclasts or excessive activity of osteoclasts. In addition, the active ingredient, which is a plant-derived natural substance, is safe due to fewer side effects on the human body compared to chemical drugs, and inhibits osteoclast progenitor cells independently of estrogen, and thus can be widely used in osteoporosis occurring due to various causes other than menopause.
COMPOSITION FOR INHIBITING OSTEOCLASTS CONTAINING AGASTACHE RUGOSA EXTRACT AS ACTIVE INGREDIENT, AND USE THEREOF
The Agastache rugosa extract or the isoagastachoside or crude polysaccharide fraction included in the extract according to the present invention can be prepared based on plants being domestically cultivated, and thus is advantageous in terms of time and cost, and can effectively inhibit the differentiation, growth, and bone resorption functions of osteoclast progenitor cells, thus increasing bone density and the like, and accordingly, can be effectively used for the prevention, amelioration, or treatment of diseases related to bone loss caused by differentiation into osteoclasts or excessive activity of osteoclasts. In addition, the active ingredient, which is a plant-derived natural substance, is safe due to fewer side effects on the human body compared to chemical drugs, and inhibits osteoclast progenitor cells independently of estrogen, and thus can be widely used in osteoporosis occurring due to various causes other than menopause.
Traditional Chinese medicine for dispersing lung qi and detoxicating
Provided are a traditional Chinese medicine for dispersing lung qi and detoxicating, a preparation method therefor, use thereof, and an analysis method. The traditional Chinese medicine contains a traditional Chinese medicine active extract. The active extract is composed of a first extract and, a second extract, herein the first extract is a water extract or an alcohol-water extract of ephedra, bitter apricot seed, raw gypsum, coix seed, rhizome of swordlike atractylodes, patchouli, Polygonum cuspidatum, verbena, reed rhizome, lepidium seed, pummelo peel, and artemisia annua, the second extract is a water extract or an alcohol-water extract of licorice, and the first extract and the second extract are separately obtained. This traditional Chinese medicine may be used for treating coronavirus diseases, such as novel coronavirus pneumonia.
Traditional Chinese medicine for dispersing lung qi and detoxicating
Provided are a traditional Chinese medicine for dispersing lung qi and detoxicating, a preparation method therefor, use thereof, and an analysis method. The traditional Chinese medicine contains a traditional Chinese medicine active extract. The active extract is composed of a first extract and, a second extract, herein the first extract is a water extract or an alcohol-water extract of ephedra, bitter apricot seed, raw gypsum, coix seed, rhizome of swordlike atractylodes, patchouli, Polygonum cuspidatum, verbena, reed rhizome, lepidium seed, pummelo peel, and artemisia annua, the second extract is a water extract or an alcohol-water extract of licorice, and the first extract and the second extract are separately obtained. This traditional Chinese medicine may be used for treating coronavirus diseases, such as novel coronavirus pneumonia.