A borate diester of chlorogenic acid is prepared by reacting a solution comprising chlorogenic acid and boric acid in a ratio of at least 2:1 in a superheated water solvent or an aqueous acetonitrile solvent. If aqueous acetonitrile is used as a solvent, the acetonitrile solvent is evaporated to leave a water solution. A product containing the desired borate diester is obtained by freeze-drying or air-drying the water solution. Insufficient levels of boron in a microbiome in a subject in need thereof may be treated by administering the borate diester of chlorogenic acid to the subject.

Disclosed is the obtaining of exosomes from coffee, ginkgo-biloba, and ginseng plants and making tablets from the exosomes. The use of plant-derived exosomes obtained from coffee, ginkgo-biloba, and ginseng, with high bio-compatibility, cellular uptake, stability, and much more ability to penetrate the blood-brain barrier is also disclosed in the treatment of Alzheimer's disease, cognitive dysfunction, forgetfulness, and poor concentration disorders.

Disclosed is a skin care composition providing anti-inflammation benefits. The composition is comprising of coffee seed oil and a hydroxy-substituted C.sub.8-C.sub.24 fatty acid being 12-hydroxy stearic acid, wherein the weight ratio of the coffee seed oil to the hydroxy-substituted C8-C24 fatty acid is 1:5 to 15:1.

A composition and its use in manufacturing a medicament or supplement for treating or reversing diabetes, particularly type 2 diabetes. The composition comprises Bitter melon fruit extract, Celery seed extract, Bakers yeast cell wall extract, Acerola fruit extract, Grape seed extract, Green tea leaf extract, Hydrolyzed soy protein powder, maybe also comprises Green coffee bean extract.

Various aspects of this patent document relate to liquid compositions comprising cannabidiol, which have either freezing points or glass-liquid transition temperatures less than the melting point of pure cannabidiol.

Generally, compositions effective for the reduction of fat deposition and/or enhancement of muscle mass. In particular, compositions including admixtures of dry ingredients or admixtures of dry ingredients combined with a carrier composition to aid delivery of constituents of the admixture of dry ingredients.

A composition for upregulating the immune system, endocannabinoid system and main bodily systems while promoting mental stability for optimal wellness. Also provided is a method for enhancing/stimulating the immune, endocannabinoid and/or main bodily systems of a patient, particularly a mammal with a disease or disorder, which includes a step of administering the composition to the patient. The composition includes a combination of Mushroom Spore Oil and/or Spore Powder and at and at least one of b1) a cannabinoid, b2) DMSO/Dimethyl Sulfoxide, b3) minerals, b4) botanicals, b5) Vitamins, b6) Amino Acids, and b7) fungi.

The present disclosure relates to a composition comprising an active ingredient or drug for degenerative disorders, one or more plant-derived neuroprotective ingredients and one or more nutraceutically or pharmaceutically acceptable excipient and a method of preparing the same. The composition delivers the active ingredient or the drug to the predetermined location of the body with success.

Various aspects of this patent document relate to liquid compositions comprising cannabidiol, which have either freezing points or glass-liquid transition temperatures less than the melting point of pure cannabidiol.

Particles, aqueous dispersions, and liquid compositions having high lipophilic component concentrations and high lipophilic component to surfactant ratios are described. The particles, aqueous dispersions, and liquid compositions can be used to efficiently deliver active compounds and/or active ingredients, such as cannabinoids including cannabidiol (CBD), through a variety of formulation types.