Described herein are Mpro cysteine protease inhibitors and methods of utilizing such inhibitors in the treatment of diseases, disorders, or conditions. Also described herein are pharmaceutical compositions containing such compounds.

Described herein are Mpro cysteine protease inhibitors and methods of utilizing such inhibitors in the treatment of diseases, disorders, or conditions. Also described herein are pharmaceutical compositions containing such compounds.

A method for improving body shape and improving skin condition using a noni fruit ferment is provided, and the method includes: administrating a composition to a subject in need thereof. The composition includes an effective amount of noni fruit ferment. The noni fruit ferment is prepared by (a) mixing glucose and noni fruit with water for extraction, to obtain a noni fruit broth, and (b) fermenting the noni fruit broth with a plurality of bacteria strains. The bacteria strains include yeast, lactic acid bacteria, and acetic acid bacteria. In step (b), the noni fruit broth and the bacteria strains are irradiated with a red light source with a wavelength of 620 nm to 750 nm. In addition, the noni fruit ferment also has at least one of the following functions: removing free radicals, improving defecation status, and improving gastrointestinal motility.

A method for improving body shape and improving skin condition using a noni fruit ferment is provided, and the method includes: administrating a composition to a subject in need thereof. The composition includes an effective amount of noni fruit ferment. The noni fruit ferment is prepared by (a) mixing glucose and noni fruit with water for extraction, to obtain a noni fruit broth, and (b) fermenting the noni fruit broth with a plurality of bacteria strains. The bacteria strains include yeast, lactic acid bacteria, and acetic acid bacteria. In step (b), the noni fruit broth and the bacteria strains are irradiated with a red light source with a wavelength of 620 nm to 750 nm. In addition, the noni fruit ferment also has at least one of the following functions: removing free radicals, improving defecation status, and improving gastrointestinal motility.

A method for improving body shape and improving skin condition using a noni fruit ferment is provided, and the method includes: administrating a composition to a subject in need thereof. The composition includes an effective amount of noni fruit ferment. The noni fruit ferment is prepared by (a) mixing glucose and noni fruit with water for extraction, to obtain a noni fruit broth, and (b) fermenting the noni fruit broth with a plurality of bacteria strains. The bacteria strains include yeast, lactic acid bacteria, and acetic acid bacteria. In step (b), the noni fruit broth and the bacteria strains are irradiated with a red light source with a wavelength of 620 nm to 750 nm. In addition, the noni fruit ferment also has at least one of the following functions: removing free radicals, improving defecation status, and improving gastrointestinal motility.

The present invention relates to a composition for enhancing exercise capacity and recovery from fatigue containing fermented and aged noni, coconut sugar or muscovado sugar as an active ingredient, and more specifically, to a composition enhancing exercise capacity and recovery from fatigue, which has the effects of enhancing exercise capacity and inhibiting the accumulation of fatigue substances in blood by increasing glycogen storage in tissue and liver function. The present invention provides a food composition for exercise capacity enhancement and anti-fatigue, which is useful in the food industry. The composition of the present invention enables recovery from fatigue or enhancement of athletic ability to be achieved quickly by promoting the reduction of fatigue substances, and may provide sports drink products, functional food products and pharmaceutical composition products that are effective in enhancing recovery from fatigue and exercise capacity.

The present invention relates to a composition for enhancing exercise capacity and recovery from fatigue containing fermented and aged noni, coconut sugar or muscovado sugar as an active ingredient, and more specifically, to a composition enhancing exercise capacity and recovery from fatigue, which has the effects of enhancing exercise capacity and inhibiting the accumulation of fatigue substances in blood by increasing glycogen storage in tissue and liver function. The present invention provides a food composition for exercise capacity enhancement and anti-fatigue, which is useful in the food industry. The composition of the present invention enables recovery from fatigue or enhancement of athletic ability to be achieved quickly by promoting the reduction of fatigue substances, and may provide sports drink products, functional food products and pharmaceutical composition products that are effective in enhancing recovery from fatigue and exercise capacity.

A composition of nutritional powder from germinated dragon fruit seeds was obtained from the process steps performed in the following specific order: (i) preparing materials, (ii) creating a dried germinated dragon fruit seeds mixture having moisture content lower than 10%, (iii) creating a foundation mixture, (iv) checking homogeneously of the foundation mixture, (v) determining whether adding the noni powder ingredient, (vi) creating a first temporary mixture, (vii) determining whether adding the dragon fruit powder ingredient, (viii) creating a second temporary mixture, (ix) determining whether adding the other ingredients, (x) creating a third temporary mixture, (xi) checking homogeneously of the third temporary mixture, (xii) grinding, and (xiii) adjusting humidity having less than 10%, then packing, and storing at room temperature. The composition of nutritional powder from germinated dragon fruit seeds is convenient for users to bring to eat/drink directly or to dilute with water and/or other food solutions when using.

A composition of nutritional powder from germinated dragon fruit seeds was obtained from the process steps performed in the following specific order: (i) preparing materials, (ii) creating a dried germinated dragon fruit seeds mixture having moisture content lower than 10%, (iii) creating a foundation mixture, (iv) checking homogeneously of the foundation mixture, (v) determining whether adding the noni powder ingredient, (vi) creating a first temporary mixture, (vii) determining whether adding the dragon fruit powder ingredient, (viii) creating a second temporary mixture, (ix) determining whether adding the other ingredients, (x) creating a third temporary mixture, (xi) checking homogeneously of the third temporary mixture, (xii) grinding, and (xiii) adjusting humidity having less than 10%, then packing, and storing at room temperature. The composition of nutritional powder from germinated dragon fruit seeds is convenient for users to bring to eat/drink directly or to dilute with water and/or other food solutions when using.

A composition of nutritional powder from germinated dragon fruit seeds was obtained from the process steps performed in the following specific order: (i) preparing materials, (ii) creating a dried germinated dragon fruit seeds mixture having moisture content lower than 10%, (iii) creating a foundation mixture, (iv) checking homogeneously of the foundation mixture, (v) determining whether adding the noni powder ingredient, (vi) creating a first temporary mixture, (vii) determining whether adding the dragon fruit powder ingredient, (viii) creating a second temporary mixture, (ix) determining whether adding the other ingredients, (x) creating a third temporary mixture, (xi) checking homogeneously of the third temporary mixture, (xii) grinding, and (xiii) adjusting humidity having less than 10%, then packing, and storing at room temperature. The composition of nutritional powder from germinated dragon fruit seeds is convenient for users to bring to eat/drink directly or to dilute with water and/or other food solutions when using.