An anxiolytic composition includes a synergistic combination of one or more of an extract of magnolia, an extract of phellodendron, an L-theanine, a whey protein composition, and/or an s-adenosylmethionine (SAMe).

An anxiolytic composition includes a synergistic combination of one or more of an extract of magnolia, an extract of phellodendron, an L-theanine, a whey protein composition, and/or an s-adenosylmethionine (SAMe).

An anxiolytic composition includes a synergistic combination of one or more of an extract of magnolia, an extract of phellodendron, an L-theanine, a whey protein composition, and/or an s-adenosylmethionine (SAMe).

Compositions for treating a sleep disorder or modifying or improving the sleep-wake cycle in a subject are disclosed herein. In some examples, the composition can comprise one or more sleep promoting active agents, one or more sleep quality active agents, one or more sleep recovery active agents, and optionally one or more next day active agents. The composition can provide an immediate burst release of the one or more sleep promoting active agents, a delayed burst or delayed sustained release of the one or more sleep quality active agents, a delayed burst or delayed sustained release of the one or more sleep recovery active agents, and a delayed burnt or delayed sustained release of the one or more next day active agents. The composition can be provided as a daily oral uni-dosage form. Methods of making and using the compositions are also provided.

Compositions for treating a sleep disorder or modifying or improving the sleep-wake cycle in a subject are disclosed herein. In some examples, the composition can comprise one or more sleep promoting active agents, one or more sleep quality active agents, one or more sleep recovery active agents, and optionally one or more next day active agents. The composition can provide an immediate burst release of the one or more sleep promoting active agents, a delayed burst or delayed sustained release of the one or more sleep quality active agents, a delayed burst or delayed sustained release of the one or more sleep recovery active agents, and a delayed burnt or delayed sustained release of the one or more next day active agents. The composition can be provided as a daily oral uni-dosage form. Methods of making and using the compositions are also provided.

Provided is an A.C.C. extract from a combination of medicinal herbs, which are Phellodendron bark, Scutellaria baicalensis, Paeonia lactiflora Pall, Dictamnus dasycarpus Turcz, Anemarrhena asphodeloides, Alumen, Dryobalanops aromatica Gaertner, Mentha arvensis var. piperascens, Inula helenium, Syringa velutina var. kamibayashii, Corydalis incisa, Eclipta prostrata, Lonicera japonica, and Glycyrrhiza uralensis, and a composition having the same as an active ingredient. The A.C.C. extract of the present invention reduces production of TNF-α IL-1β and IL-6, thereby regulating the expression of iNOS and thus exhibiting an anti-inflammatory effect inhibiting NO production. Also clinically, the A.C.C. extract of the present invention is a substance that alleviates symptoms such as diaper rash and miliaria through anti-inflammatory and antimicrobial activitities and can be used as an effective anti-inflammatory agent.

Provided is an A.C.C. extract from a combination of medicinal herbs, which are Phellodendron bark, Scutellaria baicalensis, Paeonia lactiflora Pall, Dictamnus dasycarpus Turcz, Anemarrhena asphodeloides, Alumen, Dryobalanops aromatica Gaertner, Mentha arvensis var. piperascens, Inula helenium, Syringa velutina var. kamibayashii, Corydalis incisa, Eclipta prostrata, Lonicera japonica, and Glycyrrhiza uralensis, and a composition having the same as an active ingredient. The A.C.C. extract of the present invention reduces production of TNF-α IL-1β and IL-6, thereby regulating the expression of iNOS and thus exhibiting an anti-inflammatory effect inhibiting NO production. Also clinically, the A.C.C. extract of the present invention is a substance that alleviates symptoms such as diaper rash and miliaria through anti-inflammatory and antimicrobial activitities and can be used as an effective anti-inflammatory agent.

Provided is an A.C.C. extract from a combination of medicinal herbs, which are Phellodendron bark, Scutellaria baicalensis, Paeonia lactiflora Pall, Dictamnus dasycarpus Turcz, Anemarrhena asphodeloides, Alumen, Dryobalanops aromatica Gaertner, Mentha arvensis var. piperascens, Inula helenium, Syringa velutina var. kamibayashii, Corydalis incisa, Eclipta prostrata, Lonicera japonica, and Glycyrrhiza uralensis, and a composition having the same as an active ingredient. The A.C.C. extract of the present invention reduces production of TNF-α IL-1β and IL-6, thereby regulating the expression of iNOS and thus exhibiting an anti-inflammatory effect inhibiting NO production. Also clinically, the A.C.C. extract of the present invention is a substance that alleviates symptoms such as diaper rash and miliaria through anti-inflammatory and antimicrobial activitities and can be used as an effective anti-inflammatory agent.

A traditional Chinese medicine composition for treating EGFR-TKIs related skin rash and a use thereof, characterized by comprising a therapeutically effective amount of the following components: honeysuckle, dandelion, radix sophorae flavescentis, Kochia scoparia, Dictamnus dasycarpus, tree peony root barks, Cortex Phellodendri, and peppermint. The traditional Chinese medicine composition for treating EGFR-TKIs related skin rash has a certain effect for the treatments of EGFR-TKIs related skin rash and paronychia. The raw materials coordinate with each other, thus can play medicinal effects to a maximum extent, thus significantly improving life quality of patients and prolonging survival period of patients. In addition, the traditional Chinese medicine composition also has advantages of non-toxic side effects and lower treatment cost.

A traditional Chinese medicine composition for treating EGFR-TKIs related skin rash and a use thereof, characterized by comprising a therapeutically effective amount of the following components: honeysuckle, dandelion, radix sophorae flavescentis, Kochia scoparia, Dictamnus dasycarpus, tree peony root barks, Cortex Phellodendri, and peppermint. The traditional Chinese medicine composition for treating EGFR-TKIs related skin rash has a certain effect for the treatments of EGFR-TKIs related skin rash and paronychia. The raw materials coordinate with each other, thus can play medicinal effects to a maximum extent, thus significantly improving life quality of patients and prolonging survival period of patients. In addition, the traditional Chinese medicine composition also has advantages of non-toxic side effects and lower treatment cost.