The present application includes a method for introducing a hormone directly into an affected area within a tumor. The method includes penetrating the affected area of the tumor with a biopsy needle in order to obtain a biopsy specimen. The specimen is withdrawn along with the biopsy needle. A hormone implant is inserted into the void space left behind as the specimen was removed. The method may also include directly inserting the implant and a treating substance into the tumor without the removal of the biopsy specimen. The implant may have various shapes in order to maximize surface contact. The implant is also configured to have a time release function to regulate dosage delivery.

This invention relates generally to methods for increasing bioactivity of lunasin in liquid formulations, sonicated bioactive lunasin compositions and methods of using sonicated bioactive lunasin. More specifically, this invention relates to methods of increasing bioactivity of lunasin in liquid formulations by administering sonication. One embodiment the present invention provides a method of increasing the bioactivity of lunasin comprising: a) providing a composition comprising lunasin, b) putting said composition into solution, and c) administering sonication to the composition.

The present disclosure provides a pathogen inactivation method, which is low-frequency sonication together with illumination of a photosensitizer-containing blood sample; and the low-frequency sonication is conducted at a frequency of 15-500 KHz. Through the combination of sonication and photochemical pathogen inactivation technology that enhance and complement each other, the blood pathogen inactivation method provided by the present disclosure enhances a pathogen inactivation effect, reduces a dosage of the photosensitizer, photosensitizer-related blood quality damage, energy demand for the illumination, and pathogen inactivation treatment time, increases the blood illumination thickness for effective pathogen inactivation, saves illumination bag materials, shortens the size of illumination equipment, saves costs, and helps the pathogen inactivation technology go to the market.

Reactive oxygen species (ROS) generated with noninvasive ultrasound and sonosensitizers, potently synergize with selected immunomodulators to hyperactivate dendritic cells and macrophages at desired locations and times within the body. Together with the tumor antigens provided by dying/dead tumor cells, these signals can result in activation of adaptive immune responses. This approach is useful for eliciting T cell responses within tumors present in any tissue of the body.

Reactive oxygen species (ROS) generated with noninvasive ultrasound and sonosensitizers, potently synergize with selected immunomodulators to hyperactivate dendritic cells and macrophages at desired locations and times within the body. Together with the tumor antigens provided by dying/dead tumor cells, these signals can result in activation of adaptive immune responses. This approach is useful for eliciting T cell responses within tumors present in any tissue of the body.

The present invention refers to a process for preparing a salt solution comprising sodium chloride and extracts of parts of officinal plants, preferably extracts of olive tree leaves; the invention is further directed to the salt solution itself, optionally enriched in iodine, particularly in a spray formulation, and to its uses as food supplement, as flavour enhancer for reducing salt consumption and for preventing cardiovascular and renal diseases, osteoporosis, and diseases related to salt abuse and/or iodine insufficiency in the diet.

The present invention refers to a process for preparing a salt solution comprising sodium chloride and extracts of parts of officinal plants, preferably extracts of olive tree leaves; the invention is further directed to the salt solution itself, optionally enriched in iodine, particularly in a spray formulation, and to its uses as food supplement, as flavour enhancer for reducing salt consumption and for preventing cardiovascular and renal diseases, osteoporosis, and diseases related to salt abuse and/or iodine insufficiency in the diet.

The invention provides compositions and methods for targeted controlled drug release. The compositions and methods can be used for treating or imaging vascular stenosis, stenotic lesions, occluded lumens, embolic phenomena, thrombotic disorders and internal hemorrhage.

The invention provides compositions and methods for targeted controlled drug release. The compositions and methods can be used for treating or imaging vascular stenosis, stenotic lesions, occluded lumens, embolic phenomena, thrombotic disorders and internal hemorrhage.

The present invention refers to a process for preparing a salt solution comprising sodium chloride and extracts of parts of officinal plants, preferably extracts of olive tree leaves; the invention is further directed to the salt solution itself, optionally enriched in iodine, particularly in a spray formulation, and to its uses as food supplement, as flavour enhancer for reducing salt consumption and for preventing cardiovascular and renal diseases, osteoporosis, and diseases related to salt abuse and/or iodine insufficiency in the diet.