A61K6/097

PHOSPHOCALCIC CEMENT COMPOSITION COMPRISING BLOOD

A method for promoting spine fusion inside intersomatic cages, comprising placing a fusion cage between two vertebral bodies, and injecting a bone cement paste inside said fusion cage, said bone cement paste containing a powder component comprising -tricalcium phosphate (-TCP) particles having an average size greater than or equal to 9 m, and a liquid component comprising blood.

METHOD AND APPARATUS FOR IMPROVING OSSEOINTEGRATION, FUNCTIONAL LOAD, AND OVERALL STRENGTH OF INTRAOSSEOUS IMPLANTS

The present invention enables modification of an intraosseous implant device that is not only biologically non-inert, but can stimulate bone and vascular growth; decrease localized inflammation; and fight local infections. The method of the present invention provides a fiber with any of the following modifications: (1) Nanofiber with PDGF, (2) Nanofiber with PDGF+BMP2, and (3) Nanofiber with BMP2 and Ag. Nanofiber can be modified with other growth factors that have been shown to improve bone growth and maturationBMP and PDGF being the most common. Nanofiber can be applied on the surface of the implant in several ways. First, a spiral micro-notching can be applied on the implant in the same direction as the threads with the nanofibers embedded into the notches. Second, the entire surface of the implant may be coated with a mesh of nanofibers. Third, it can be a combination of both embedding and notching.

CHITOSAN-CALCIUM PHOSPHATE COMPOSITE AS ODONTOINDUCTIVE DENTAL FILLINGS AND METHODS OF MAKING AND USING
20190224373 · 2019-07-25 ·

A dental or bone material comprising a polysaccharide, diepoxide and calcium phosphate. The polysaccharide can be a chitosan, and the polysaccharide is modified to be soluble. The combination of the polysaccharide and diepoxide form a gel, which can be cured to form the implant. The curing does not require equipment, but instead the material is self-curing. Methods of making and using the material are also disclosed.

Injectable, biodegradable bone cements and methods of making and using same

Compositions of, methods of making, and methods of using alkaline earth phosphate bone cements are disclosed. A bone cement composition includes a powder comprising a basic source of calcium, magnesium, or strontium, a setting solution comprising H3PO4 and a buffer, and a biocompatible polymer that is incorporated into the setting solution. The powder is mixed with the setting solution to form a bone cement paste that either (a) sets into a hardened mass, or (b) is irradiated with electromagnetic radiation to form dry powders, the dry powders then being mixed with a second setting solution to form a radiation-assisted bone cement paste that sets into a hardened mass.

Cellulose cyanoacrylate and method of employment
10327998 · 2019-06-25 ·

Cellulose cyanoacrylate is employed to bond two surfaces, fill voids or duplicate the shape of a three-dimensional object, Two surfaces may be bonded by placing a sheet of cellulose material between the surfaces and applying cyanoacrylate glue around the edge of the sheet until saturated and allowing it to cure. Paper toweling may favorably be employed as the cellulose material. A break or fracture in an article can be overlaid with a sheet of cellulose that when saturated with cyanoacrylate glue and temporarily held in place and shaped with a releasable film, the fracture can be corrected. A dry powder comprising highly abrasion-resistant particles can be mixed with the cellulose material to enhance abrasion resistance and to improve long-term color stabilityespecially important for dental cavity treatment. To duplicate the shape of a three-dimensional object, a sheet of releasable film is placed over the object, followed by a sheet of cellulose that is then saturated with cyanoacrylate glue. A sheet of releasable film is then placed over the cellulose and used to hold the cellulose in place and shape it as it hardens.

PHOSPHOCALCIC CEMENT COMPOSITION COMPRISING BLOOD

A bone cement paste containing a powder component comprising -tricalcium phosphate (-TCP) particles having an average size greater than or equal to 9 m, and a liquid component comprising blood is disclosed. A method for preparation of the phosphocalcic cement composition is also disclosed.

Dental curable composition

The present invention relates to providing a dental curable composition that, when cured, has high metal ion release ability and highly durable physical properties. The dental curable composition of the present invention includes: a sugar compound having an XM group, where X is an acid anion group and M is a metal cation; and a curable component.

Fine and Uniform Methyl Vinyl Ether-Maleic Acid Inorganic Salt Copolymers and Their Use in Oral Care and Pharmaceutical Applications

The invention relates to fine and uniform copolymer powders of partial mixed metal salts of lower alkyl vinyl ether-maleic acid copolymers having a defined particle size distribution. In particular; it relates to powders that are suitably used in the areas of oral care and pharmaceuticals and to methods for preparing the powders. Provided is a composition of powders of partial mixed metal salts of lower alkyl vinyl ether-maleic acid copolymers having: (i) a Dv50 of less than or equal to 25 microns; a Dv90 of less than or equal to 50 microns; and (ii) a particle uniformity reflected by a Dv90/Dv10 ratio of less than or equal to 10.

KIT OF PARTS FOR PRODUCING A PASTE TYPE GLASS IONOMER CEMENT, PROCESS OF PRODUCTION AND USE THEREOF

The invention relates to a kit of parts for preparing a glass ionomer composition for dental use, the kit comprising a Paste A and a Paste B, Paste A comprising water, acid-reactive inorganic filler A, phyllo silicate(s), Paste B comprising water, poly-acid, non acid-reactive filler B, optionally chelating agent. The invention also relates to a hardenable composition obtainable by combining the pastes of the kit or parts and to the use of such a composition as or for preparing a dental cement, dental filling mater ial, dental core build up material or dental root channel filling material.

Curable dental retraction composition, method of production and use thereof

The invention relates to a curable dental retraction composition comprising alginate and a solvent, with the proviso that essentially no crosslinker in an amount effective to start setting of the curable dental retraction composition is present. The invention also relates to a container containing said composition and to a kit comprising two parts, wherein the first part comprises the curable dental retraction composition of the present invention and the second part comprises a crosslinker being able to start setting of the dental retraction composition.