A61K6/56

Dental pulp construct

Disclosed is a method for filling a root canal in a tooth. The method includes positioning a fiber in the root canal of the tooth, filling at least a portion of the root canal with an unset hydrogel composition, such that the unset hydrogel composition contacts at least a portion of the fiber, setting the hydrogel composition, thereby forming a set hydrogel, and removing the fiber from the set hydrogel, thereby leaving a channel in the set hydrogel. Methods and kits for repairing teeth are also described.

Dental pulp construct

Disclosed is a method for filling a root canal in a tooth. The method includes positioning a fiber in the root canal of the tooth, filling at least a portion of the root canal with an unset hydrogel composition, such that the unset hydrogel composition contacts at least a portion of the fiber, setting the hydrogel composition, thereby forming a set hydrogel, and removing the fiber from the set hydrogel, thereby leaving a channel in the set hydrogel. Methods and kits for repairing teeth are also described.

PHOTOSENSITISING COMPOSITION AND USES THEREOF

The present invention provides a photosensitising composition comprising a mixture of: at least one surfactant; at least one alcohol; and/or water, with the proviso that when the at least one surfactant is an alcohol, it is different from the at least one alcohol. In particular, the composition may comprise a mixture of glycerol, ethanol and water. Alternatively, the composition may comprise a mixture of polyethylene glycol, ethanol and water. The photosensitising composition may further comprise at least one photosensitising compound. The present invention also provides a method of treating and/or preventing conditions caused by microorganisms in a subject.

PHOTOSENSITISING COMPOSITION AND USES THEREOF

The present invention provides a photosensitising composition comprising a mixture of: at least one surfactant; at least one alcohol; and/or water, with the proviso that when the at least one surfactant is an alcohol, it is different from the at least one alcohol. In particular, the composition may comprise a mixture of glycerol, ethanol and water. Alternatively, the composition may comprise a mixture of polyethylene glycol, ethanol and water. The photosensitising composition may further comprise at least one photosensitising compound. The present invention also provides a method of treating and/or preventing conditions caused by microorganisms in a subject.

Composition for single-paste type hydraulic endodontic filling material comprising dimethyl sulfoxide
11517508 · 2022-12-06 · ·

The present invention relates to a composition for a single-paste type hydraulic endodontic filling material comprising dimethyl sulfoxide (DMSO). According to one aspect of the invention, there is provided a single-paste type hydraulic endodontic filling composition, comprising a calcium silicate component and DMSO.

Composition for single-paste type hydraulic endodontic filling material comprising dimethyl sulfoxide
11517508 · 2022-12-06 · ·

The present invention relates to a composition for a single-paste type hydraulic endodontic filling material comprising dimethyl sulfoxide (DMSO). According to one aspect of the invention, there is provided a single-paste type hydraulic endodontic filling composition, comprising a calcium silicate component and DMSO.

Composition for single-paste type hydraulic endodontic filling material comprising dimethyl sulfoxide
11517508 · 2022-12-06 · ·

The present invention relates to a composition for a single-paste type hydraulic endodontic filling material comprising dimethyl sulfoxide (DMSO). According to one aspect of the invention, there is provided a single-paste type hydraulic endodontic filling composition, comprising a calcium silicate component and DMSO.

PULP REGENERATION COMPOSITIONS AND METHODS OF FORMING AND USING THE SAME
20230037361 · 2023-02-09 ·

A dental tissue regenerative composition. The composition includes a combination of (1) human dental pulp stem cells and (2) at least one of human umbilical vein endothelial cells or vascular endothelial growth factor. The combination is encapsulated in a light-activated gelatin methacrylate hydrogel.

PULP REGENERATION COMPOSITIONS AND METHODS OF FORMING AND USING THE SAME
20230037361 · 2023-02-09 ·

A dental tissue regenerative composition. The composition includes a combination of (1) human dental pulp stem cells and (2) at least one of human umbilical vein endothelial cells or vascular endothelial growth factor. The combination is encapsulated in a light-activated gelatin methacrylate hydrogel.

Electro-conductive and anti-bacterial composite material, for endodontic use

A gutta-percha-silver composite with determined weight percentage and particle size, is provided. The composite exhibits electro-conductivity greater than the standard gutta-percha composites. The new material simplifies root canal treatments, shortens the times both for clinician and patients, and reduces the exposure to patients from X-rays. The material is not only electro-conductive; it is anti-bacterial, which improves the outcomes of the procedures. Also, it has improved thermal conductivity, and mechanical properties.