Described is a milling blank for producing an indirect dental restoration, composed of resin or a resin-based composite, containing water in an amount of at least 25% of the water sorption W.sub.sp. Described is further a method for producing such a milling blank or a moulded part produced therefrom for use as an indirect dental restoration, a use of the water sorption method, a kit for producing indirect dental restorations and a method for indirect dental restoration.

Described is a milling blank for producing an indirect dental restoration, composed of resin or a resin-based composite, containing water in an amount of at least 25% of the water sorption W.sub.sp. Described is further a method for producing such a milling blank or a moulded part produced therefrom for use as an indirect dental restoration, a use of the water sorption method, a kit for producing indirect dental restorations and a method for indirect dental restoration.

A natural and sustainable material is derived from the nut of the tagua palm tree that may be fashioned into devices for humans and animals. A pulverized and reconstituted material is disclosed herein that is also treated with a low temperature atmospheric plasma treatment. In an embodiment, a biocompatible carrier gas is ionized to form a biocompatible atmospheric plasma stream. Material, such as nano-scale powdered hydroxyapatite, is introduced into the plasma stream, which is then applied to the natural nut material.

Provided is a dental pretreatment material for dental tissue regeneration by use of dental pulp stem cells, particularly a dental pretreatment material effectively enabling dental tissue regeneration even by use of dental pulp stem cells of middle-aged or older individuals. The dental pretreatment material is characterized by comprising a serine protease, specifically trypsin. The dental pretreatment material comprising trypsin is used as an injection into a root canal before a root canal filling material comprising dental pulp stem cells and an extracellular matrix is inserted into the root canal as an attempt to regenerate a dental pulp and a dentin. The root canal filling material includes an ALK5 inhibitor, a CCR3 antagonist, or a CCL11 neutralizing antibody.

Provided is a dental pretreatment material for dental tissue regeneration by use of dental pulp stem cells, particularly a dental pretreatment material effectively enabling dental tissue regeneration even by use of dental pulp stem cells of middle-aged or older individuals. The dental pretreatment material is characterized by comprising a serine protease, specifically trypsin. The dental pretreatment material comprising trypsin is used as an injection into a root canal before a root canal filling material comprising dental pulp stem cells and an extracellular matrix is inserted into the root canal as an attempt to regenerate a dental pulp and a dentin. The root canal filling material includes an ALK5 inhibitor, a CCR3 antagonist, or a CCL11 neutralizing antibody.

The present invention relates to a composition for a single-paste type hydraulic endodontic filling material comprising dimethyl sulfoxide (DMSO). According to one aspect of the invention, there is provided a single-paste type hydraulic endodontic filling composition, comprising a calcium silicate component and DMSO.

The present invention relates to a composition for a single-paste type hydraulic endodontic filling material comprising dimethyl sulfoxide (DMSO). According to one aspect of the invention, there is provided a single-paste type hydraulic endodontic filling composition, comprising a calcium silicate component and DMSO.

A natural and sustainable material is derived from the nut of the tagua palm tree that may be fashioned into devices for humans and animals. A pulverized and reconstituted material is disclosed herein that is also treated with a low temperature atmospheric plasma treatment. In an embodiment, a biocompatible carrier gas is ionized to form a biocompatible atmospheric plasma stream. Material, such as nano-scale powdered hydroxyapatite, is introduced into the plasma stream, which is then applied to the natural nut material.

The present invention provides a dental curable composition that shows fluorescence sufficient to enable highly aesthetic harmonious restoration almost indistinguishable from surrounding natural teeth, and that, while having sufficient mechanical strength and radiopacity and good ease of polishing as a restorative material, desirably resists discoloration not only in the intraoral environment but under accelerated heating conditions and under xenon light, without losing fluorescence even under these conditions. The present invention also provides a cured product of such a dental curable composition. The present invention relates to a dental curable composition comprising a polymerizable monomer (A), an inorganic filler (B), a polymerization initiator (C), and a fluorescent agent (D), wherein the fluorescent agent (D) comprises a 9- to 11-membered benzo-fused heterocyclic compound containing two or more heteroatoms (excluding benzoimidazole compounds).

The present invention provides a dental curable composition that shows fluorescence sufficient to enable highly aesthetic harmonious restoration almost indistinguishable from surrounding natural teeth, and that, while having sufficient mechanical strength and radiopacity and good ease of polishing as a restorative material, desirably resists discoloration not only in the intraoral environment but under accelerated heating conditions and under xenon light, without losing fluorescence even under these conditions. The present invention also provides a cured product of such a dental curable composition. The present invention relates to a dental curable composition comprising a polymerizable monomer (A), an inorganic filler (B), a polymerization initiator (C), and a fluorescent agent (D), wherein the fluorescent agent (D) comprises a 9- to 11-membered benzo-fused heterocyclic compound containing two or more heteroatoms (excluding benzoimidazole compounds).