A rinse off hair treatment composition comprising; a. a pressure sensitive adhesive emulsion comprising one or more pressure sensitive polymer, wherein the pressure sensitive polymer is not silicone pressure sensitive polymer, and b. at least one material selected from the group consisting of i) a hair conditioning agent; ii) a hair cleansing agent, and, c. a deposition aid.

A cosmetic composition for make-up removal that provides aesthetically pleasing gliding application and is smudge resistant, the composition being provided in the form of a water-based micellar make-up removal composition that includes a blend of surfactants that includes one surfactant that has an HLB that is in the range from about 8 to about 16 and at least one surfactant that has an HLB that is greater than 16, and one or more powdered polysaccharides provided as essentially water-insoluble particles. In some embodiments the surfactant with an HLB greater than 16 is amphoteric. The composition can also include one or more of each or a combination of inorganic mineral powders, humectants, silicone-based defoaming agents, preservatives, and other cosmetically acceptable additives.

The invention relates to nano-sized complexes formed by associating amorphous calcium phosphate (ACP) and/or amorphous calcium fluoride phosphate (ACFP) with an amphiphilic polymer surfactant. The amphiphilic polymer surfactants can form nano-sized assemblies in aqueous solution, serving as a nano dispersant preventing ACP and/or ACFP from aggregation, and as a nano carrier associating or attaching ACP and/or ACFP, stabilizing ACP and/or ACFP against the conversion to a crystalline form as well, thus maintaining calcium and phosphate/and fluoride ions in a bioavailable state for dental re-mineralization and prevention of dental caries, dental calculus and dental hyper-sensitivity. A method for the nano-sized complex preparation and compositions comprising the nano-sized complexes are also provided.

The present invention provides nanoparticle compositions comprising AE nanoparticles. The present invention provides AE nanoparticles comprising one or more amphiphilic entities and pharmaceutical compositions comprising AE nanoparticles. The present invention provides methods of manufacturing AE nanoparticles. The present invention provides methods of delivering a biologically active agent to a subject by administering AE nanoparticles containing a biologically active agent to a subject.

A method for skin care and/or maintenance including applying or administering a preparation to a subject is provided. The preparation includes a biomedical composition, and the biomedical composition includes an effective amount of micelle, wherein the micelle includes a hyaluronic acid and/or a derivative thereof and a modified histidine. The modified histidine is grafted to at least one primary hydroxyl group of the hyaluronic acid and/or the derivative thereof, and a graft ratio of the modified histidine is 1-100%. Moreover, the hyaluronic acid and/or the derivative thereof and the modified histidine form the micelle on a weight percentage of 0.2-300:1.

Improved formulations for topical treatment that ensure at least localized transdermal or systemic delivery of an active agent through skin, nails or hair follicles are disclosed.

A cosmetic composition including a metal chelation system includes a combination of ascorbic acid, ferulic acid and phytic acid in a carrier system that includes water, and further includes one or more other ingredients for providing one of a variety of forms of cosmetic products. The cosmetic composition demonstrates removal of free metal ions in material contacted with the cosmetic composition, the removal of free metal ions in a range from at least about 40% and up to about 99%.

An antimicrobial personal cleansing composition comprises: (i) an aqueous continuous phase including cleansing surfactant, (ii) a dispersed phase including dispersed particles of zinc-containing antimicrobial agents; and (iii) a solubilised oily liquid conditioning agent for skin and/or hair; which is light mineral oil having a kinematic viscosity of 3 to 5 cS (mm.sup.2.Math.s.sup.−1) at 40° C. and is solubilised in wormlike micelles in the aqueous continuous phase via the incorporation of an inorganic electrolyte and a linker molecule of formula R(X).sub.n, wherein R is a C.sub.6-C.sub.10 aryl ring or a C.sub.3-C.sub.14 mono-, di- or trivalent alkyl or hydroxyalkyl chain; n is 1 to 3 and each X is independently selected from —OH, —COOH and —COO.sup.−M.sup.+ groups, where M is an alkali metal, ammonium or alkanolammonium cation; and in which the level of solubilised oily liquid conditioning agent is 0.45 to 3% by weight based on the total weight of the composition.

Methods for forming dermatological compositions that deliver water and/or other hydrophilic compounds into or through the dermis using reverse micelles. The methods include forming compositions with an oil-based continuous phase and an emulsifier that form nanoparticle micelles. The nanoparticle micelles are formulated into biocompatible topical ointments that are stable at room temperature and can be distributed in consumer packaging and consumer distribution channels.

A nonaqueous composition for external use on the skin including a strongly hydrophilic amphiphilic solid active ingredient-surfactant complex dissolved or dispersed as a particle having a particle size of 2 nm to 200 nm in an oil phase. A strongly hydrophilic amphiphilic solid active ingredient-surfactant complex dissolved or dispersed as a particle having a particle size of 2 nm to 200 nm in the oil phase can be prepared by: adding a strongly hydrophilic amphiphilic solid active ingredient to a water phase to obtain a water phase mixture; adding a surfactant to an oil phase to obtain an oil phase mixture; mixing the obtained water phase mixture with the oil phase mixture to obtain a water-in-oil emulsion; freeze-drying the water-in-oil emulsion to obtain a strongly hydrophilic amphiphilic solid active ingredient-surfactant complex; and dissolving or dispersing the obtained strongly hydrophilic amphiphilic solid active ingredient-surfactant complex in an oil.