A method of increasing the solubility of a water-insoluble or slightly water-soluble hydrophobic organic compound in an aqueous solvent includes adding a saponin component selected from escin, glycyrrhizin, and Quillaya saponaria extract to the aqueous solvent in an amount sufficient to trigger the formation of micelles, wherein in a first step the hydrophobic organic compound is pre-dissolved in an organic solvent, and in a second step the organic solvent comprising the pre-dissolved compound is admixed to the aqueous solvent, whereby at least a part of the insoluble or slightly soluble hydrophobic organic compound gets solubilized and dissolved in the aqueous solvent, yielding an aqueous composition having an increased concentration of said organic compound dissolved therein. Also indicated are pharmaceutical or cosmetic compositions including a water-insoluble or slightly water-soluble organic compound dissolved in an aqueous solvent at substantially increased concentrations.

Improved formulations for topical treatment that ensure at least localized transdermal or systemic delivery of an active agent through skin, nails or hair follicles are disclosed.

The present invention relates to a gas-generating micelle for reducing localized fat. In the present invention, by forming a micelle using a material having high biocompatibility and also introducing a cell-targeting ligand (peptide) onto the surface of the micelle, delivery to surrounding cells and tissues other than adipocytes can be minimized, and delivery into adipocytes can be maximized. The gas-generating micelle for reducing localized fat according to the present invention can be produced as an injectable preparation, and can be applied to local lipolysis supplements or diet beauty products that break down localized fat.

A personal cleansing composition includes a surfactant system, wherein the surfactant system includes from 0.1% to 5% of a fatty acyl isethionate surfactant by weight of the composition; from 0.5% to 40% of a co-surfactant by weight of the composition; from 0.05% to 5% of a natural polysaccharide or a chemically modified natural polysaccharide by weight of the composition; wherein the personal cleansing composition includes a first and second phase, wherein the first phase is an isotropic and micellar surfactant phase; wherein the second phase is a polymer liquid crystalline phase; wherein the composition is free of alkyl sulfate and alkyl ether sulfate type of surfactants; wherein the composition exhibits a yield stress value τ.sub.y from 0.005 Pa to 3 Pa; and wherein the composition exhibits a flow viscosity from 3 Pa.Math.s to 100 Pa.Math.s at 25° C. at a shear rate of 1.5 s.sup.−1.

A non-rinse micellar water composition; method of manufacture for a non-rinse micellar water composition; and a method of use for a micellar water composition are disclosed.

Improved formulations for topical treatment that ensure at least localized transdermal or systemic delivery of an active agent through skin, nails or hair follicles are disclosed.

The present invention relates to potassium hydrogen alkylhydroxamate compounds and compositions and formulations comprising same, processes for preparing the inventive potassium hydrogen alkylhydroxamate compounds, as well as applications thereof including the use of the inventive compounds and compositions in formulations of products or components of products.

The present invention relates to biobased polyglyceryl ester compounds and compositions and formulations comprising same, processes for preparing the inventive biobased polyglyceryl ester compositions, as well as applications thereof including the use of the inventive compounds and compositions in formulations of products or components of products. The biobased polyglyceryl ester composition may comprise a mixture including one or more compounds of Formula (I):

##STR00001## wherein: PG is a polyglyceryl group comprising greater than 40% hexaglycerol and higher polyglycerols and less than 60% pentaglycerol and lower polyglycerols, R is a linear or branched C.sub.5-C.sub.8 alkyl group, n=from 1 to 3, and wherein substantially all of the carbon present in the one or more compounds of Formula (I) is biobased.

A personal cleansing composition includes a surfactant system, wherein the surfactant system includes from 0.1% to 5% of a fatty acyl isethionate surfactant by weight of the composition; from 0.5% to 40% of a co-surfactant by weight of the composition; from 0.05% to 5% of a natural polysaccharide or a chemically modified natural polysaccharide by weight of the composition; wherein the personal cleansing composition includes a first and second phase, wherein the first phase is an isotropic and micellar surfactant phase; wherein the second phase is a polymer liquid crystalline phase; wherein the composition is free of alkyl sulfate and alkyl ether sulfate type of surfactants; wherein the composition exhibits a yield stress value τ.sub.y from 0.005 Pa to 3 Pa; and wherein the composition exhibits a flow viscosity from 3 Pa.Math.s to 100 Pa.Math.s at 25° C. at a shear rate of 1.5 s.sup.−1.

A composition comprising lipid and surfactant, characterised in that the surfactant has an HLB number of less than 20 and in that the lipid and surfactant are in the form of macromolecular assemblies of less than 10 nm in diameter.