Methods of inhibiting the growth of Porphyromonas gingivalis (“P. gingivalis”) in the oral cavity using cannabinoid compounds are described herein. The cannabinoid compounds can include one or more of cannabinol cannabigerol (“CBG”), cannabigerolic acid (“CBGA”), cannabidiolic acid (“CBDA”), and (+)-cannabidiol (“((+)-CBD”), cannabichromene (“CBC”), cannabinol (“CBN”), cannabidivarin (“CBDV”), cannabidol (“CBD”), cannabidol-C.sub.4 (“CBD-C.sub.4”), cannabigerivarin (“CBGV”), cannabigerol butyl (“CBG-C4”), cannabichromenic acid (“CBCA”), cannabicyclolic acid (“CBLA”), and cannabinolic acid (“CBNA”), cannabidol-C.sub.2 (“CBD-C.sub.2”) and cannabigerolic acid butyl (“CBGA-C4”). The methods can be used to treat or prevent periodontal disease. Compositions and articles including the cannabinoid compounds are further disclosed.

Methods of inhibiting the growth of Porphyromonas gingivalis (“P. gingivalis”) in the oral cavity using cannabinoid compounds are described herein. The cannabinoid compounds can include one or more of cannabinol cannabigerol (“CBG”), cannabigerolic acid (“CBGA”), cannabidiolic acid (“CBDA”), and (+)-cannabidiol (“((+)-CBD”), cannabichromene (“CBC”), cannabinol (“CBN”), cannabidivarin (“CBDV”), cannabidol (“CBD”), cannabidol-C.sub.4 (“CBD-C.sub.4”), cannabigerivarin (“CBGV”), cannabigerol butyl (“CBG-C4”), cannabichromenic acid (“CBCA”), cannabicyclolic acid (“CBLA”), and cannabinolic acid (“CBNA”), cannabidol-C.sub.2 (“CBD-C.sub.2”) and cannabigerolic acid butyl (“CBGA-C4”). The methods can be used to treat or prevent periodontal disease. Compositions and articles including the cannabinoid compounds are further disclosed.

[Problem to be Solved] An object of the present invention is to provide an aqueous antimicrobial composition which exhibits excellent antibacterial and antifungal activities even at a low concentration and has high safety, low skin irritation, and excellent long-term stability. [Solution] Aqueous antimicrobial compositions comprising two or more compounds selected from (a) benzoic acid or a salt thereof, (b) δ-gluconolactone, (c) ketonic acid or a salt thereof, and (d) sorbic acid or a salt thereof; and at least one or more dicarboxylic acid represented by General Formula (I) or a salt thereof.

[Problem to be Solved] An object of the present invention is to provide an aqueous antimicrobial composition which exhibits excellent antibacterial and antifungal activities even at a low concentration and has high safety, low skin irritation, and excellent long-term stability. [Solution] Aqueous antimicrobial compositions comprising two or more compounds selected from (a) benzoic acid or a salt thereof, (b) δ-gluconolactone, (c) ketonic acid or a salt thereof, and (d) sorbic acid or a salt thereof; and at least one or more dicarboxylic acid represented by General Formula (I) or a salt thereof.

The present invention relates to personal care compositions comprising malodor reduction compositions and methods of making and using such personal care compositions. Such personal care compositions comprising the malodor control technologies disclosed herein provide malodor control without leaving an undesireable scent and when perfume is used to scent such compositions, such scent is not unduely altered by the malodor control technology.

The present invention relates to personal care compositions comprising malodor reduction compositions and methods of making and using such personal care compositions. Such personal care compositions comprising the malodor control technologies disclosed herein provide malodor control without leaving an undesireable scent and when perfume is used to scent such compositions, such scent is not unduely altered by the malodor control technology.

The present disclosure relates to antiperspirant cosmetic agents, in the case of which the total amount of antiperspirant compounds can be clearly reduced without the antiperspirant effect of said agents or the storage stability of said agents being impaired, comprising—in each case with respect to the total weight of the antiperspirant cosmetic agent—a) 1 to 30 wt % of at least one antiperspirant compound, b) 0.1 to 10 wt % of salicylic acid, c) at least one compound of formula (I), in which n represents 0 or 1, X represents —H, Na+, K+, or NH4+, R1 is selected from —H, —COOX, or —(CH2)—COOX, R2 is selected from —H, C1-10 alkyl, or COOX, R3 is selected from —(CH2)—COOX, —(CH2)2-N[(CH2)—COOX]2, —CH(R1)—COOX, —(CH2)2-NH[CH(COOX)(CH2COOX)], —CH(R4)—C(R5)(R6)—COOX, R4 is selected from —H, C1-10 alkyl, or COOX, and R5 and R6 are, independently of each other, —H, —OH, or C1-10 alkyl.

The present disclosure relates to antiperspirant cosmetic agents, in the case of which the total amount of antiperspirant compounds can be clearly reduced without the antiperspirant effect of said agents or the storage stability of said agents being impaired, comprising—in each case with respect to the total weight of the antiperspirant cosmetic agent—a) 1 to 30 wt % of at least one antiperspirant compound, b) 0.1 to 10 wt % of salicylic acid, c) at least one compound of formula (I), in which n represents 0 or 1, X represents —H, Na+, K+, or NH4+, R1 is selected from —H, —COOX, or —(CH2)—COOX, R2 is selected from —H, C1-10 alkyl, or COOX, R3 is selected from —(CH2)—COOX, —(CH2)2-N[(CH2)—COOX]2, —CH(R1)—COOX, —(CH2)2-NH[CH(COOX)(CH2COOX)], —CH(R4)—C(R5)(R6)—COOX, R4 is selected from —H, C1-10 alkyl, or COOX, and R5 and R6 are, independently of each other, —H, —OH, or C1-10 alkyl.

In some embodiments, a composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals. In some embodiments, a composition is disclosed that includes silk fibroin-based protein fragments and is suitable for use in consumer applications. In some embodiments, a preserved composition is disclosed that includes silk fibroin-based protein fragments. In some embodiments, a method of preserving a solution using silk fibroin-based protein fragments is disclosed.

In some embodiments, a composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals. In some embodiments, a composition is disclosed that includes silk fibroin-based protein fragments and is suitable for use in consumer applications. In some embodiments, a preserved composition is disclosed that includes silk fibroin-based protein fragments. In some embodiments, a method of preserving a solution using silk fibroin-based protein fragments is disclosed.