A61K8/65

DEGRADABLE DELIVERY PARTICLES BASED FROM AMINE CONTAINING NATURAL MATERIALS
20230049775 · 2023-02-16 · ·

An improved delivery particle comprising a benefit agent core material and a shell encapsulating the core material is described, along with a process for forming such a delivery particle and articles of manufacture. The shell is the reaction product of: i) an isocyanate or acid chloride or acrylate with ii) an amine-containing natural material having free amino moieties, and iii) an a, β -unsaturated compound, the a, β -unsaturated compound forming C-N covalent bonds with the amine moieties of the natural material. The delivery particle of the invention has improved release characteristics, with enhanced degradation characteristics in OECD test method 301B.

PHYSICAL MIX HA-COLLAGEN DERMAL FILLERS

The disclosure relates to compositions comprising crosslinked hyaluronic acid physically mixed with collagen. Also contemplated are methods of improving an aesthetic quality of an anatomic feature of a human being.

PHYSICAL MIX HA-COLLAGEN DERMAL FILLERS

The disclosure relates to compositions comprising crosslinked hyaluronic acid physically mixed with collagen. Also contemplated are methods of improving an aesthetic quality of an anatomic feature of a human being.

CROSSLINKED HA-COLLAGEN HYDROGELS AS DERMAL FILLERS

The present disclosure relates to a crosslinked macromolecular matrix comprising lysine; hyaluronic acid; and collagen; wherein the hyaluronic acid is crosslinked to the collagen by at least one endogenous amine group on the collagen and/or by at least one amine group present on the lysine.

CROSSLINKED HA-COLLAGEN HYDROGELS AS DERMAL FILLERS

The present disclosure relates to a crosslinked macromolecular matrix comprising lysine; hyaluronic acid; and collagen; wherein the hyaluronic acid is crosslinked to the collagen by at least one endogenous amine group on the collagen and/or by at least one amine group present on the lysine.

BIOLOGICAL HAIR SHAPE CHANGE COMPOSITION AND KIT, AND METHOD FOR CHANGING HAIR SHAPE

A biological hair shape change composition including a macromolecular component, a small molecular component and an alkali agent component is provided. The macromolecular component includes a protease belonging to the class of alkaline proteases, and the small molecular component includes a peptide with reduction activity. Both the macromolecular component and the small molecular component are obtained from a fermentation product of Bacillus licheniformis and a keratin and/or keratin polymer-containing medium. Molecular weights of ingredients in the macromolecular component are greater than or equal to 3 kDa and are 3-1000 kDa, and molecular weights of ingredients in the small molecular component are less than 3 kDa and are 0.01-2.99 kDa.

BIOLOGICAL HAIR SHAPE CHANGE COMPOSITION AND KIT, AND METHOD FOR CHANGING HAIR SHAPE

A biological hair shape change composition including a macromolecular component, a small molecular component and an alkali agent component is provided. The macromolecular component includes a protease belonging to the class of alkaline proteases, and the small molecular component includes a peptide with reduction activity. Both the macromolecular component and the small molecular component are obtained from a fermentation product of Bacillus licheniformis and a keratin and/or keratin polymer-containing medium. Molecular weights of ingredients in the macromolecular component are greater than or equal to 3 kDa and are 3-1000 kDa, and molecular weights of ingredients in the small molecular component are less than 3 kDa and are 0.01-2.99 kDa.

Pet cleansing composition
11590069 · 2023-02-28 ·

A composition and method are provided. The composition may be a cleansing and conditioning composition for an animal. The composition may include, a solvent, a thickening agent, a conditioning agent comprising a rice protein, and a botanical agent. The composition may be free of a lathering agent and suitable for use in cleansing and conditioning an animal.

PEPTIDIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES OF SAID COMPOUNDS, IN PARTICULAR COSMETIC USES

The peptidic compound comprises at least an aminoacid which is lysine, ornithine, diaminopropionic acid or diaminobutyric acid or a derivative of these aminoacids, on which a carboxylic acid is grafted via a peptidic bound on the nitrogen of the lateral chain, said carboxylic acid comprising a (poly)cycle or (poly)heterocycle. Preferably, the grafted carboxylic acid is an aminoacid or a derivative, in particular selected from, a proline, a hydroxyproline or pyroglutamic acid.

The peptidic compound can stimulate the synthesis of the main molecules constituting the extracellular matrix of the skin, especially collagen 1 and 4 and elastin. It can be used for topical cosmetic treatment such as a global anti-aging treatment, or for specific activities, including anti-wrinkles, moisturizing, to improve the mechanical properties of the skin, firmness/tone/elasticity/flexibility, to increase density and volume of the skin, improve skin radiance, for a restructuring effect and/or to fight stretch marks.

PEPTIDIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES OF SAID COMPOUNDS, IN PARTICULAR COSMETIC USES

The peptidic compound comprises at least an aminoacid which is lysine, ornithine, diaminopropionic acid or diaminobutyric acid or a derivative of these aminoacids, on which a carboxylic acid is grafted via a peptidic bound on the nitrogen of the lateral chain, said carboxylic acid comprising a (poly)cycle or (poly)heterocycle. Preferably, the grafted carboxylic acid is an aminoacid or a derivative, in particular selected from, a proline, a hydroxyproline or pyroglutamic acid.

The peptidic compound can stimulate the synthesis of the main molecules constituting the extracellular matrix of the skin, especially collagen 1 and 4 and elastin. It can be used for topical cosmetic treatment such as a global anti-aging treatment, or for specific activities, including anti-wrinkles, moisturizing, to improve the mechanical properties of the skin, firmness/tone/elasticity/flexibility, to increase density and volume of the skin, improve skin radiance, for a restructuring effect and/or to fight stretch marks.