A dressing for treating tissue may be a composite of dressing layers, including a contact layer, a manifold layer, and an adhesive drape. The manifold layer may include one or more layers of felted open-cell foam in some examples. The manifold layer may be relatively thin to reduce the dressing profile and increase flexibility, which can enable it to conform to difficult geometry and other tissue sites under negative pressure. The dressing may have a length and a width less than the length. The manifold layer may include a population of holes extending at least partially therethrough, wherein the holes may be configured to promote anisotropic contraction of the dressing parallel to its width. The population of holes may have a circular, ovoid, triangular, square, hexagonal, irregular, or morphous shape. The dressing may be a bolster that may anisotropically contract to provide a closing force to a linear wound.

A system for managing female incontinence includes a body of biocompatible material configured to fit between the labia minora and the vestibule floor, the body having a surface configured to occlude the urethral meatus, an adhesive carried on at least a first portion of the surface and configured to provide a sealing engagement between the body and the urethral meatus, and a substance carried by at least one of the body and the adhesive and configured for controlling the odor of the general vaginal-urethral area of a female.

Provided is an absorbent article having excellent shape retention of an absorber even when an external force is applied thereto. The present invention is an absorbent article having: an aqueous-liquid absorbing part having crosslinked polymer particles having as essential constitutional units thereof a water-soluble vinyl monomer and/or a vinyl monomer which became the water-soluble vinyl monomer by hydrolysis, and a crosslinking agent; and a nonwoven fabric having porous fibers as an essential constituent thereof, the crosslinked polymer particles preferably absorbing 40 times the weight thereof of physiological saline 40 in 40-150 seconds.

A wound covering is provided that comprises a substrate and vitamin D, or analogues or metabolites thereof, embedded in the substrate. Methods of making a wound covering are also provided and include the steps of providing a solution that includes a polymer; adding vitamin D, or analogues or metabolites thereof, to the solution to form a mixture; and forming one or more fibers from the mixture that are then embedded with the vitamin D, or analogues or metabolites thereof. Methods of treating a subject are further provided and include the step of applying a wound covering including one or more fibers embedded with vitamin D, or analogues or metabolites thereof, to a site on a subject.

The present invention is directed to novel non-woven fabrics containing growth and differentiation factor proteins. Said fabrics are specifically designed to accelerate tissue regeneration and wound healing processes of mammalian tissues. Furthermore, the invention provides wound dressings, pads or implants comprising the novel non-woven fabrics.

An absorbent article having a liquid permeable topsheet, a liquid impermeable sheet, an absorbent core disposed between the topsheet and the backsheet, and a secondary topsheet disposed between the topsheet and the absorbent core is described. The secondary topsheet has a first layer and a second layer. The first layer is located between the topsheet and the second layer, and a mean pore size of the first layer is larger than a mean pore size of the topsheet.

A bandage to control bleeding from an open wound has a hemostatic gauze. An absorbent pad is removably attached to the hemostatic gauze.

A wound therapy device is disclosed. The wound therapy device may include a housing for covering at least a portion of a wound and for sealing to a body surface of a patient. The housing may also include a liquid collector for retaining liquid therein and a vacuum connection for coupling to a vacuum source. The vacuum connection may be in gaseous communication with the liquid collector. The vacuum connection may be separated from the liquid collector by a liquid barrier.

A method of promoting hemostasis in the mouth or oral cavity utilizes a non-absorbent, low surface energy and highly conformable non-disruptive hemostasis material. Traditional wound packing material is highly absorbent and has large open surfaces that allow clot forming materials, such as the platelet plug to adhere to the packing material and whereupon removal, the clot is disrupted. A non-disruptive highly conformable hemostasis material does not have large open pores and therefore does not adhere to forming clots. A non-disruptive hemostasis material may consist of expanded polytetrafluoroethylene that has a pore size of no more than about 10 microns. A non-disruptive hemostasis material may comprise a thin film of material over a portion of the outside surface that is non-absorbent and thin to allow for conforming into an oral cavity, such as from a tooth extraction. A thin film may cover porous material, such as a foam, that may be elastomeric.

A method for manufacturing a wound dressing having a substrate, and a wound dressing manufactured by such a method are described. The method has a step of providing a sacrificial layer of material to be perforated by means of a hot pin perforator, in order to remove any molten residues on the heated pins of the hot pin perforator, before the same pins are used to make holes in the substrate. The presented method is cost effective, robust and reduces the risk of contaminating substances being embedded in the substrate during the hole making process.