Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic acid-based compositions described herein include a therapeutically effective amount of at least one anesthetic agent, for example, lidocaine. The present hyaluronic acid-based compositions including lidocaine have an enhanced stability and cohesivity, relative to conventional compositions including lidocaine, for example when subjected to sterilization techniques or when stored for long periods of time. Methods and processes of preparing such hyaluronic acid-based compositions are also provided.

A system for detecting presence of coronavirus in a subject, the system including a first pad for placing a first hand, the pad including a contact to measure conductance of the subject's body, a conductance meter connected to the contact, a second pad for placing a second hand, a source of electromagnetic radiation for irradiating the second pad. A system for detecting presence of coronavirus in a subject, the system including a chip with a plurality of wires disposed on or in the chip, a conductance meter arranged to measure conductance between the wires, and biological material associated with the coronavirus disposed on or in the chip. Related apparatus and methods are also described.

The invention relates to a container (1) for holding a transplant object (2) and to a closure lid (4) and a vessel (3) for such a container (1). To facilitate an improved and reliable analysis and treatment of transplant objects (2), the intention being to implement particularly sparing handling, which is also protected against environmental influences, of the transplant object (2), it is proposed that the container (1) be transmissive for radiation that facilitates radiological imaging and/or a sterilization by means of ionizing radiation of the transplant object (2) held in the container (1) and that the closure lid (4) and/or the vessel (3) have one or more affixment structures (5) for fastening the transplant object (2) in the container (1). Moreover, a method and a system for providing three-dimensional structure data of a transplant object are proposed, by means of which the information obtained by the analysis is rendered better usable for medical staff. Moreover, a method and a system for sterilizing a transplant object (2) by means of ionizing radiation are described.

Sterilisation apparatus comprising a sterilisation instrument configured to be inserted through the instrument channel of a surgical scoping device and a withdrawal device for withdrawing the sterilisation instrument from the instrument channel at a predetermined rate. The sterilisation instrument comprises an elongate probe having a probe tip with a first electrode and a second electrode arranged to produce an electric field from received RF and/or microwave frequency EM energy. In operation the instrument may disinfect an inner surface of the instrument channel by emitting energy whilst being withdrawn through the channel.

Disclosed is an activation device. The activation device, which serves as a device coming into contact with an object to activate surrounding materials according to a dielectric barrier discharge principle, includes: a dielectric having a predetermined thickness and formed with an outer surface coming into contact with the object and an inner surface facing the outer surface; and an electrode provided inside the dielectric and having an outer surface facing the inner surface of the dielectric, wherein the outer surface of the electrode includes a contact area that comes into contact with the inner surface of the dielectric, and a non-contact area that does not come into contact with the inner surface of the dielectric.

Disclosed herein are soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. Some of the hyaluronic acid-based compositions can include a therapeutically effective amount of at least one anesthetic agent, for example, lidocaine. Compared to conventional compositions that include lidocaine, some of the hyaluronic acid-based compositions disclosed herein can have an enhanced stability, for example, when subjected to sterilization techniques or when stored for long periods of time. Methods and processes of preparing such compositions are also provided.

A system for detecting presence of coronavirus in a subject, the system including a first pad for placing a first hand, the pad including a contact to measure conductance of the subject's body, a conductance meter connected to the contact, a second pad for placing a second hand, a source of electromagnetic radiation for irradiating the second pad.

A system for detecting presence of coronavirus in a subject, the system including a chip with a plurality of wires disposed on or in the chip, a conductance meter arranged to measure conductance between the wires, and biological material associated with the coronavirus disposed on or in the chip.

Related apparatus and methods are also described.

A method for the inactivation of viruses and/or bacteria by at least 50%, or the disinfection and sanitization from bacteria and/or viruses, in spaces, surfaces or objects uses an electromagnetic radiation having a wavelength comprised between 410 nm and 430 nm. In particular, it relates to irradiating the area to be disinfected or sanitized with an electromagnetic radiation having a wavelength comprised between 410 nm and 430 nm for a time interval between 5 minutes and 180 minutes, a power density comprised between 13 mW/cm.sup.2 and 120 mW/cm.sup.2 and an energy density comprised between 30 J/cm.sup.2 and 220 J/cm.sup.2. The electromagnetic radiation is irradiated at a distance between the source of the electromagnetic radiation and the irradiated space, surface or object between 30 centimeters to 1.5 meters.

Provided are methods for preparing pathogen-inactivated platelet compositions, as well as processing sets and compositions related thereto.

Disclosed herein are methods of making sterilized ciprofloxacin compositions. In some embodiments, the method includes the steps of: (a) forming an aqueous suspension comprising ciprofloxacin particles; (b) heating the aqueous suspension comprising ciprofloxacin particles at a temperature range of from about 100° C. to about 120° C.; and (c) allowing the aqueous suspension comprising ciprofloxacin particles to cool down. Also described herein are otic formulations containing ciprofloxacin formed by the disclosed methods, and therapeutic use of such otic formulation for providing sustained release of ciprofloxacin into the ear for treating various otic disorders and conditions.