A61L2300/11

Antimicrobial hydrocolloid dressing containing sequestered peroxide and preparation thereof

This disclosure provides a hydrocolloid having a super absorbent material chemically bonded either directly or indirectly to a peroxide. The peroxide is within the hydrocolloid and the peroxide is in an amount of 0.05% to 2% by weight within the hydrocolloid.

STABILIZED ACTIVE OXYGEN-GENERATING ANTISEPTIC COMPOSITIONS, IRRIGATION SOLUTIONS, AND ARTICLES
20230218660 · 2023-07-13 ·

A stabilized active oxygen-generating antiseptic composition is disclosed including at least one of an antiseptic mixture or an antiseptic polymer. The antiseptic mixture includes a persulfate distributed in a matrix of a sulfate wherein the antiseptic composition is characterized by a ratio of the sulfate to the persulfate of at least 8:2. The antiseptic polymer is formed by the reaction of a sulfate, a persulfate, and amino acid in a reaction solution having a ratio of the sulfate to the persulfate of at least 6:4 and a ratio of the amino acid to the sulfate and the persulfate combined of 1:2 to 2:1. An antiseptic irrigation solution is disclosed including the antiseptic composition dispersed in a solvent. An antiseptic article is disclosed including an article and at least one of the antiseptic composition or an antiseptic coating formed from the antiseptic composition disposed on a surface of the article.

OXIDANT COMPOSITION FOR SUPPRESSING LOSS OF ADHESIVE DURABILITY, AND USE OF SAME

The disclosure relates to a microbicidal composition with excellent action of limiting a decrease in durability of synthetic adhesives as well as high microbicidal action. The microbicidal composition contains 0.03 to less than 1.0 mass % of peracetic acid, 0.045 to less than 1.5 mass % of hydrogen peroxide, and 0.036 mass % or more of glycine.

OXYGEN-GENERATING WOUNDING HEALING DRESSING
20220387660 · 2022-12-08 ·

The present disclosure provides for oxygen generating and free radical scavenging biomaterials, an article including the oxygen generating and free radical scavenging biomaterial, wound healing dressings or structures (e.g., bandage) that have the characteristic of generating oxygen and having redox modulating capabilities. In particular, the wound healing dressing can have the characteristics of being anti-inflammatory, antioxidant, and pro-healing for extended periods of time (e.g., at least 10 days, at least 30 days).

Methods of producing an osteoinductive calcium phosphate material for bone grafting
11504447 · 2022-11-22 · ·

The present invention relates to methods for producing biphasic calcium phosphate materials using chemical processing methods including exposure to peroxides. The resulting materials exhibit an osteoinductive needle-like surface morphology and are useful as artificial bone grafts.

Microenvironmental gas permeable layer capable of supplying hydrogen

A gas permeable layer capable of supplying hydrogen includes a thin layer, encapsulating a hydrogen production formula. An outer side of the thin layer is airtight. An inner side is air-permeable. An inner side surface has a plurality of small holes. The thin layer can be a single layer or a composite layer. The hydrogen production formula does not dissipate. The hydrogen production formula absorbs moisture in the air or liquid water, thereby generating hydrogen. The hydrogen is released onto the skin and into the human body through the small holes. The hydrogen production formula includes metal peroxides, metal hydroxides, or metal hydrides and aluminum powder, or microsilica. The gas permeable layer can be used in sanitary products including eye masks, mouth masks, face masks, cosmetic facial masks, bras, pasties, nursing pads, sanitary napkins (towels), diapers, panty liners, wound dressing, woundplasts, bandage gauze, decubitus pads.

Stabilized active oxygen-generating antiseptic compositions, irrigation solutions, and articles

A stabilized active oxygen-generating antiseptic composition is disclosed including at least one of an antiseptic mixture or an antiseptic polymer. The antiseptic mixture includes a persulfate distributed in a matrix of a sulfate wherein the antiseptic composition is characterized by a ratio of the sulfate to the persulfate of at least 8:2. The antiseptic polymer is formed by the reaction of a sulfate, a persulfate, and amino acid in a reaction solution having a ratio of the sulfate to the persulfate of at least 6:4 and a ratio of the amino acid to the sulfate and the persulfate combined of 1:2 to 2:1. An antiseptic irrigation solution is disclosed including the antiseptic composition dispersed in a solvent. An antiseptic article is disclosed including an article and at least one of the antiseptic composition or an antiseptic coating formed from the antiseptic composition disposed on a surface of the article.

Method for Treating Tissue

Methods for treating tissue are provided. In one embodiment, an adjunct material, when secured to tissue, can receive at least one physiological element released from the tissue during healing progression of the tissue, and can exhibit first and second stiffnesses in compression that are approximately constant during first and second time periods from contact with the tissue, with the second stiffness decreasing with time as a function of at least one of oxidation, enzyme-catalyzed hydrolysis, and change of pH resulting from interaction with the at least one physiological element. In another embodiment, the adjunct can receive a unit volume of fluid that causes first and second portions of the adjunct to expand according to first and second expansion behaviors that differ from one another to apply different pressures to the tissue.

METHODS OF PRODUCING AN OSTEOINDUCTIVE CALCIUM PHOSPHATE MATERIAL FOR BONE GRAFTING
20230181792 · 2023-06-15 ·

The present invention relates to methods for producing biphasic calcium phosphate materials using chemical processing methods including exposure to peroxides. The resulting materials exhibit an osteoinductive needle-like surface morphology and are useful as artificial bone grafts.