A bone replacement material having reinforcing elements and a modelable mass which is curable on contact with water or an aqueous liquid. as well as a process for producing a bone replacement material, to a further bone replacement material and to medical kits for treatment of bone defects.

A discovery of the conversion of amorphous calcium polyphosphate (ACPP) or/and other polyphosphate salts with various type of calcium phosphate to new calcium phosphate product (i.e. dicalcium phosphate dihydrate (DCPD)) in a liquid environment. The discovery includes mixing a various type of calcium phosphate with an aqueous ACPP or/and other polyphosphate salts gel, which is fast setting and possessing strong mechanical strength, and can be gradually converted to DCPD/hydroxyapatites in physiological condition. This injectable past can be applied as alternative of conventional CPC bone cement that is suitable for bone void repair due to its excellent properties in osteoconductivity and osseointegration. It can also be applied as drug delivery device in tissue engineering for its strong bonding to drug molecules.

A bone replacement material having reinforcing elements and a modelable mass which is curable on contact with water or an aqueous liquid as well as a process for producing a bone replacement material, to a further bone replacement material and to medical kits for treatment of bone defects.

A discovery of the conversion of amorphous calcium polyphosphate (ACPP) or/and other polyphosphate salts with various type of calcium phosphate to new calcium phosphate product (i.e. dicalcium phosphate dihydrate (DCPD)) in a liquid environment. The discovery includes mixing a various type of calcium phosphate with an aqueous ACPP or/and other polyphosphate salts gel, which is fast setting and possessing strong mechanical strength, and can be gradually converted to DCPD/hydroxyapatites in physiological condition. This injectable past can be applied as alternative of conventional CPC bone cement that is suitable for bone void repair due to its excellent properties in osteoconductivity and osseointegration. It can also be applied as drug delivery device in tissue engineering for its strong bonding to drug molecules.