An article, at least a surface of the article being made of or containing an organic material, and a thermally sprayed layer of coating material on the surface.

This invention relates to the field of medical technology, and can be used in dentistry and traumatology, in particular when creating dental implants. Namely, the invention relates to the development and creation of a method for producing a dental implant characterized by high strength, as well as increased ability to activate the process of osteogenesis and osseointegration. The implant obtained by this method is characterized by high biocompatibility, bactericidal properties (reduces pronounced dystrophic and necrotic processes of living tissue), and an increased level of implant surface strength.

Disclosed are an implantable medical device, a preparation method thereof and an implantable medical device preform for the preparation of the implantable medical device. The implantable medical device comprises a metal basal body (21) and a polymer film layer (22) covering the surface of the metal basal body (21) and preventing endothelium growth and covering, and also comprises a transitional body (23), which is located between the metal basal body (21) and the polymer film layer (22) and covers at least part of the surface of the metal basal body (21), wherein the transitional body (23) is connected to the polymer film layer (22) and the metal basal body (21). By arranging the transitional body (23) to be connected to the polymer film layer (22) and the metal basal body (21), the polymer film layer (22) will not easily fall off when being implanted into a human body.

A carbo nanofiber nerve scaffold includes a cylindrical helix, a bundle of aligned carbon nanofiber yarns, and a carbon nanofiber sheet. The cylindrical helix includes a surgical suture material, and the cylindrical helix defines an interior of the carbon nanofiber nerve scaffold. The bundle of aligned carbon nanofiber yarns is disposed within the interior of the cylindrical helix. The carbon nanofiber sheet is disposed around the cylindrical helix on a side of the cylindrical helix opposite of the interior.

Orthopedic replacements include are formed at least partially of composite materials including a metal matrix with reinforcing carbon fiber integrated into the matrix. The composite materials have substantially lower density than metal, and are expected to have appreciable strength. The orthopedic replacements can include a bone attachment portion and a load bearing portion. In some versions, the orthopedic replacements can include a core formed of the composite material, with a shape completion portion, formed for example from plastic, at least partially coating the core.

Various embodiments disclosed relate to curable calcium phosphate compositions for use with porous structures and methods of using the same. In various embodiments, the present invention provides a curable calcium phosphate composition or a cured product thereof, with the curable calcium phosphate composition including calcium phosphate and a perfusion modifier. In various embodiments, the present invention provides an apparatus comprising a porous structure at least partially in contact with the curable calcium phosphate composition or a cured product thereof. The porous structure can include a porous substrate including a plurality of ligaments that define pores of the porous substrate, and a biocompatible metal coating on the plurality of ligaments of the porous substrate.

Various embodiments disclosed relate to curable calcium phosphate compositions for use with porous structures and methods of using the same. In various embodiments, the present invention provides a curable calcium phosphate composition or a cured product thereof, with the curable calcium phosphate composition including calcium phosphate and a perfusion modifier. In various embodiments, the present invention provides an apparatus comprising a porous structure at least partially in contact with the curable calcium phosphate composition or a cured product thereof. The porous structure can include a porous substrate including a plurality of ligaments that define pores of the porous substrate, and a biocompatible metal coating on the plurality of ligaments of the porous substrate.

Nerve scaffolds are described that include a tubular outer housing fabricated from a biocompatible polymer, within which are disposed a plurality of carbon nanofiber yarns. The carbon nanofiber yarns, which can be separated by distances roughly corresponding to an average nerve fiber diameter, provide surfaces on which nerve fibers can regrow. Because the proximate carbon nanofiber yarns can support individual nerve fibers, a nerve can be regenerated with a reduced likelihood of undesirable outcomes, such as nerve pain or reduced nerve function.

Orthopedic replacements include are formed at least partially of composite materials including a metal matrix with reinforcing carbon fiber integrated into the matrix. The composite materials have substantially lower density than metal, and are expected to have appreciable strength. The orthopedic replacements can include a bone attachment portion and a load bearing portion. In some versions, the orthopedic replacements can include a core formed of the composite material, with a shape completion portion, formed for example from plastic, at least partially coating the core.

Nerve scaffolds are described that include a tubular outer housing fabricated from a biocompatible polymer, within which are disposed a plurality of carbon nanofiber yarns. The carbon nanofiber yarns, which can be separated by distances roughly corresponding to an average nerve fiber diameter, provide surfaces on which nerve fibers can regrow. Because the proximate carbon nanofiber yarns can support individual nerve fibers, a nerve can be regenerated with a reduced likelihood of undesirable outcomes, such as nerve pain or reduced nerve function.