The invention provides compositions featuring chitosan and methods for using such compositions for the local delivery of biologically active agents to an open fracture, complex wound or other site of infection. Advantageously, the degradation and drug elution profiles of the chitosan compositions can be tailored to the needs of particular patients at the point of care (e.g., in a surgical suite, clinic, physician's office, or other clinical setting).

Multifunctional crosslinkers are a reaction product between a polyaziridine compound and two or more functionalized benzophenones. The polyaziridine compound is linked to the functionalized benzophenones through two or more reacted aziridine groups. Coating compositions, comprising: a polymer, and multifunctional crosslinkers. Coated medical devices, comprise a lubricious coating bonded adjacent to an exterior surface of the medical device. The lubricious coating is prepared by UV-curing a coating composition, wherein the coating composition comprises: a water/isopropyl alcohol (IPA) soluble polymer and/or a UV-curable polymer, and a water/IPA soluble multifunctional crosslinker.

The invention provides compositions featuring chitosan and methods for using such compositions for the local delivery of biologically active agents to an open fracture, complex wound or other site of infection. Advantageously, the degradation and drug elution profiles of the chitosan compositions can be tailored to the needs of particular patients at the point of care (e.g., in a surgical suite, clinic, physician's office, or other clinical setting).

A catheter drainage accessory adapted to be connected to a urinary catheter including a connector configured to be operably connected to a drainage member of a urinary catheter and a drainage conduit. At least one of the connector and conduit are made of a water flushable material.

A catheter drainage accessory adapted to be connected to a urinary catheter including a connector configured to be operably connected to a drainage member of a urinary catheter and a drainage conduit. At least one of the connector and conduit are made of a water flushable material.

Urinary catheters and methods for preventing bacterial infections.

Several embodiments of NO releasing structures are disclosed. In some embodiments, the structures are covalently modified to store and release nitric oxide. Some embodiments pertain to methods of making and use of these structures. The covalently modified polymer structures may be tailored to release nitric oxide in a controlled manner and are useful for treatment of various medical conditions.

The invention relates to a method for producing a storable molded body made of bacterial cellulose and a molded body produced according to the method. A preferred method includes providing a molded body made of bacterial cellulose. Optionally, mechanically pressing the entire molded body or parts of the molded body at temperatures in the range of 10° C. to 100° C. and pressures in the range of 0.01 to 1 MPa for a pressing time of 10-200 min. Treating the molded body with a solution of 20% by weight to 50% by weight of glycerol and 50% by weight to 80% by weight of a C1-C3-alcohol/water mixture. Drying the treated molded body.

Described are coatings for medical devices and methods of forming same.

A medical device for insertion into a natural or artificial body opening, such as a urinary catheter is described. The medical device comprises a substrate having a wall enclosing an internal cavity that forms a tubular body. The wall extends between a proximal insertion end and a distal rearward end. The wall comprises at least 30 wt % of natural fibers, such as cellulose fibers. One example medical device is, at least to a large extent, made of paper.