A vascular stent assembly includes at least a first and a second strut, each including a thickness and a depth. The assembly includes a pair of end radii, with each of the first and second struts extending from one of the pair of end radii. A thickness of at least one of the first and second struts includes a tapering profile extending from one of the end radii to another of the end radii, the tapering profile following a continuously increasing or decreasing function through at least half a length of the at least one strut.

A device for reducing pulsatile pressure within a vessel to treat heart disease, such as pulmonary hypertension, includes a compliant body structured to expand and contract upon changes in pressure within the vessel, a reservoir structured for holding a fluid therein, and a conduit extending between and fluidly coupling the reservoir and the compliant body, wherein the device includes a graphene-polymer composite designed to resist diffusion of the fluid through the device.

A biomedical device includes a zinc-based material including a matrix including zinc, and nanostructures dispersed in the matrix. Embodiments of this disclosure are directed to zinc (Zn)-based materials including dispersed nanostructures for biomedical applications and devices, such as bioresorbable vascular stents, bioresorbable ureteral stents, endoluminal springs for distraction enterogenesis, biodegradable bone implants with tunable modulus, guided bone generation membranes, bioresorbable dental membranes, and other biomedical implants, as well as other functional applications, such as biodegradable electronics and sensors.

As detailed herein, a biocompatible apparatus comprises a porous material comprising ceramic nanotubes bound together with a filler material. The proportion of the filler material may be selected to provide porosity for the porous material that is biocompatible, and the porous material may be shaped to provide a compliant biomedical device. In one embodiment, the compliant biomedical device is a stent such as intravascular stent. A method for fabricating a biocompatible device is also described herein. The method may include growing ceramic nanotubes on a substrate, infiltrating the ceramic nanotubes with a filler material to provide a porous material having a porosity that is biocompatible, and removing the porous material from the substrate to provide a biocompatible ceramic device. The method may also include coating the biocompatible ceramic device with a drug-eluting material.

Provided are an iron-based absorbable and implantable medical device and manufacturing method thereof. The iron-based absorbable and implantable medical device (1) comprises a substrate (11), a degradable polymer layer (12), and an anionic surfactant layer (13) located between the substrate (11) and the degradable polymer layer (12). The anionic surfactant, by using the hydrophobicity thereof, can form a hydrophobic barrier layer in a solution to isolate a surface of the iron-based substrate (11) from a body fluid environment, thereby avoiding direct contact with an acidic environment resulting from degradation of the degradable polymer layer (12) at the initial and early stages of implantation, thus preventing severe local corrosion of the iron-based substrate (11).

The present invention relates to composites for reflecting energy produced from a body to the body itself. Accordingly, the present invention provides composites comprising inert materials and methods of using the composites to enhance health conditions of animals by reflecting the energy produced from a body to the body itself.

A device for reducing pulsatile pressure within a vessel to treat heart disease, such as pulmonary hypertension, includes a compliant body structured to expand and contract upon changes in pressure within the vessel, a reservoir structured for holding a fluid therein, and a conduit extending between and fluidly coupling the reservoir and the compliant body, wherein the device includes a graphene-polymer composite designed to resist diffusion of the fluid through the device.

The invention entails metal alloy mono and poly-filament wire reinforced carbon fiber plating system for the fixation of skeletal fractures and osteotomies with electrical bone stimulation. For example, in some embodiments, systems and methods comprise a bone stimulation device by generating an electrical current from an implanted power pack, which travels through wire wrapped in the transverse/perpendicular plane around the mono-poly filament wires within the carbon fiber plate, creating an electromagnetic field. Such systems and methods find use in delayed or non-union events of bone and also in patients with acute bone fractures whom also suffer from other comorbidities predisposing the osteotomy or fracture to a non-union event.

Provided are an iron-based absorbable and implantable medical device and manufacturing method thereof. The iron-based absorbable and implantable medical device (1) comprises a substrate (11), a degradable polymer layer (12), and an anionic surfactant layer (13) located between the substrate (11) and the degradable polymer layer (12). The anionic surfactant, by using the hydrophobicity thereof, can form a hydrophobic barrier layer in a solution to isolate a surface of the iron-based substrate (11) from a body fluid environment, thereby avoiding direct contact with an acidic environment resulting from degradation of the degradable polymer layer (12) at the initial and early stages of implantation, thus preventing severe local corrosion of the iron-based substrate (11).

Drainage devices for draining a fluid from a patient during treatment of a medical condition body are disclosed. The drainage devices comprise a body defining at least one conduit through the body from a distal end of the body to a proximal end of the body. The body comprises at least one carbon-based structure configured to inhibit growth of fibroblasts in the conduit when the fluid flows through the conduit. Example embodiments of the drainage device may include an ophthalmic shunt, a hydrocephalus shunt, an artificial mesh, an arteriovenous shunt, a thoracic catheter, and a central venous access device.