A61L33/04

Infusion pump and infusion method dedicated for stem cell

The infusion pump for stem cells includes a liquor storage device and an infusion pipe. The inner wall of the liquor storage sac of the liquor storage device and inner walls of the infusion pipe are provided with an anionic protective film to prevent stem cells from adhering to the infusion pump by mutual repulsion between anions. The infusion method includes checking an infusion pump for integrity, losing a liquor stop clamp, injecting a mixed liquor of stem cells and medicine, covering a protective cap, opening the liquor stop clamp, closing the liquor stop clamp for use, connecting an external cone joint with a venous cannula, and then opening the liquor stop clamp. The method also includes steadily placing the liquor storage sac on a horizontal plane using an auxiliary placing device, and after infusion ends, closing the liquor stop clamp, and disconnecting the external cone joint.

Infusion pump and infusion method dedicated for stem cell

The infusion pump for stem cells includes a liquor storage device and an infusion pipe. The inner wall of the liquor storage sac of the liquor storage device and inner walls of the infusion pipe are provided with an anionic protective film to prevent stem cells from adhering to the infusion pump by mutual repulsion between anions. The infusion method includes checking an infusion pump for integrity, losing a liquor stop clamp, injecting a mixed liquor of stem cells and medicine, covering a protective cap, opening the liquor stop clamp, closing the liquor stop clamp for use, connecting an external cone joint with a venous cannula, and then opening the liquor stop clamp. The method also includes steadily placing the liquor storage sac on a horizontal plane using an auxiliary placing device, and after infusion ends, closing the liquor stop clamp, and disconnecting the external cone joint.

Hemocompatibility of superhemophobic titania surfaces

In this work, we investigated the blood platelet adhesion and activation of truly superhemophobic surfaces and compared them with that of hemophobic surfaces and hemophilic surfaces. Our analysis indicates that only those superhemophobic surfaces with a robust Cassie-Baxter state display significantly lower platelet adhesion and activation. The understanding gained through this work will lead to the fabrication of improved hemocompatible, superhemophobic medical implants.

Hemocompatibility of superhemophobic titania surfaces

In this work, we investigated the blood platelet adhesion and activation of truly superhemophobic surfaces and compared them with that of hemophobic surfaces and hemophilic surfaces. Our analysis indicates that only those superhemophobic surfaces with a robust Cassie-Baxter state display significantly lower platelet adhesion and activation. The understanding gained through this work will lead to the fabrication of improved hemocompatible, superhemophobic medical implants.

NEEDLE SURFACE FOR REDUCED COAGULATION AND METHOD FOR SAME
20170281835 · 2017-10-05 · ·

A medical needle may include a lumen coating configured to reduce surface energy of the lumen-facing/lumen defining surface, in a manner effective to slow and/or reduce coagulation of biomaterial (particularly blood) that contacts the needle lumen surface. Such a coating may include a hydrophobic coating such as a silane and/or siloxane material on at least the needle lumen surface. The coating reduces a surface energy of coated needle regions below the surface energy of uncoated regions, and particularly reduces the polar component of the surface energy in the coated needle regions. The needle may be a metallic biopsy needle with the coating comprised by at least a distalmost length of sample-collection lumen.

NEEDLE SURFACE FOR REDUCED COAGULATION AND METHOD FOR SAME
20170281835 · 2017-10-05 · ·

A medical needle may include a lumen coating configured to reduce surface energy of the lumen-facing/lumen defining surface, in a manner effective to slow and/or reduce coagulation of biomaterial (particularly blood) that contacts the needle lumen surface. Such a coating may include a hydrophobic coating such as a silane and/or siloxane material on at least the needle lumen surface. The coating reduces a surface energy of coated needle regions below the surface energy of uncoated regions, and particularly reduces the polar component of the surface energy in the coated needle regions. The needle may be a metallic biopsy needle with the coating comprised by at least a distalmost length of sample-collection lumen.

Catheter locking solution having antimicrobial and anticoagulation properties

The present invention includes a catheter locking solution having both antimicrobial and anticoagulant properties including a local anesthetic and a viscosifying agent. The local anesthetic of the present invention may be an amino amide; an amino ester; an aminoacylanilide; an aminoalkyl benzoate; an amino carbonate; an N-phenylamidine compound; an N-aminoalkyl amid; an aminoketone, or combinations and mixtures thereof. In a particular embodiment of the present invention, the local anesthetic is tetracaine or dibucaine.

Catheter locking solution having antimicrobial and anticoagulation properties

The present invention includes a catheter locking solution having both antimicrobial and anticoagulant properties including a local anesthetic and a viscosifying agent. The local anesthetic of the present invention may be an amino amide; an amino ester; an aminoacylanilide; an aminoalkyl benzoate; an amino carbonate; an N-phenylamidine compound; an N-aminoalkyl amid; an aminoketone, or combinations and mixtures thereof. In a particular embodiment of the present invention, the local anesthetic is tetracaine or dibucaine.

CLOT ADHESION PREVENTING AGENT AND BLOOD COLLECTION CONTAINER

Provided is a clot adhesion preventing agent capable of suppressing adhesion of clot to the inner wall surface of a blood collection container. The clot adhesion preventing agent according to the present invention includes a polyether compound or a silicone oil, and an amino acid.

CLOT ADHESION PREVENTING AGENT AND BLOOD COLLECTION CONTAINER

Provided is a clot adhesion preventing agent capable of suppressing adhesion of clot to the inner wall surface of a blood collection container. The clot adhesion preventing agent according to the present invention includes a polyether compound or a silicone oil, and an amino acid.