A blood component collection cassette that can trap a substance where blood components coagulate by using a simple and economical configuration, and a manufacturing method of the blood component collection cassette are provided. A blood component collection cassette (28) includes a cassette main body (40) where a flow path (42) is formed and is configured to be mountable to a centrifugal separation device (14). The cassette main body (40) has a first sheet (40a) and a second sheet (40b) which are formed of a soft material. The flow path (42) is formed between the first sheet (40a) and the second sheet (40b). A filter member (60) for trapping a substance where blood components coagulate is arranged on the flow path (42) in the cassette main body (40).

Provided is a blood component sampling cassette which can be efficiently manufactured at low cost compared to a conventional cassette, a method for manufacturing the blood component sampling cassette, a blood sampling circuit set and a blood component sampling system. The blood component sampling cassette includes a cassette main body having a plurality of flow paths including an introduction line, a blood component transfer line and a retransfusion line. The cassette main body includes a first sheet and a second sheet which are formed of a soft material compatible with autoclave sterilization. The first sheet and the second sheet are overlaid in a thickness direction and bonded to each other. A plurality of flow paths is formed between the first sheet and the second sheet.

The present invention relates to a blood bag system, a method for its manufacture, and a process for reducing pathogens and leucocytes in biological fluids in particular in therapeutic quantities of platelet concentrates (PC) contained in the blood bag system, using UV-light and agitation, wherein part of the plasma of the PC is optionally exchanged against a platelet additive solution.

Filtration systems and methods using a pump and pressure sensor are provided for improved efficiency in fluid filtration systems. A filtration system includes a pre-filter container joined to a post-filter container by a filter line having a filter. To reduce the time required for filtration a pump and pressure sensor are included in a filter inlet flow path. The pump also is used to provide air management in the system via pre-filtration evacuation of air from at least the filter.

A flow path device of a biological component bag system is equipped with a device main body. The device main body includes a first sheet and a second sheet, and flow paths are formed between the first sheet and the second sheet. The flow paths include a first flow path, a second flow path, a filter accommodating chamber, and a third flow path. In the device main body, flow path sealed portions that join the first sheet and the second sheet to each other in a liquid-tight manner are disposed along the flow paths.

A fluid processing system for controlling fluid flow comprising a cassette comprising defined passageways within a first portion of the cassette and a filter receptacle within a second portion of the cassette, an inlet port in communication with one or more of the defined passageways and an inlet side of the filter receptacle, an outlet port in communication with an outlet side of the filter receptacle, and a filter medium disposed within the filter receptacle between the inlet port and outlet port.

In a blood transfusion system (a blood transfusion kit, a blood transfusion kit for emergency blood transfusion, or a method of using a blood transfusion kit), a flow path through which blood flows is formed using a tube having a channel therein. The flow path includes: a first path that connects an upstream path and a downstream path and has a leukocyte removal filter removing leukocytes at an intermediate position of the channel and a second path that connects the upstream path and the downstream path and bypasses the leukocyte removal filter.

A blood component collection system (10) includes a first internal pressure calculation unit (110) adapted to calculate a first internal pressure of a first pressed portion (60) using first calibration curve data (118), a second internal pressure calculation unit (112) adapted to calculate a second internal pressure of a second pressed portion (62) using second calibration curve data (120), and a correction unit (114) adapted to correct the first calibration curve data (118) in a manner so that the first internal pressure becomes equal to the second internal pressure in a state in which operation of a collection and returning pump (100) is stopped during at least one of a collection operation and a returning operation of a first cycle.

In a blood transfusion system (a blood transfusion kit, a blood transfusion kit for emergency blood transfusion, or a method of using a blood transfusion kit), a flow path through which blood flows is formed using a tube having a channel therein. The flow path includes: a first path that connects an upstream path and a downstream path and has a leukocyte removal filter removing leukocytes at an intermediate position of the channel; and a second path that connects the upstream path and the downstream path and bypasses the leukocyte removal filter.

A collapsible fluid reservoir may include a flexible container, a flexible filter, a first inflow line, a second inflow line, and an outflow line. The container may include a first sheet and a second sheet defining an internal space therebetween for containing a biological fluid. The filter may be disposed within the internal space and attached to the container along an entire periphery of the filter. The filter may include a first side facing the first sheet and a second side facing the second sheet. The first inflow line and the second inflow line each may be disposed at least partially within the interior space and between the first side of the filter and the first sheet. The outflow line may be disposed at least partially within the interior space and between the second side of the filter and the second sheet.