The present invention relates to a method for preparing a macromolecular composition comprising phenylglyoxaldehyde-derivatives. The invention also relates to the macromolecular compositions per se, and to methods of using the macromolecular compositions. The macromolecular compositions are useful for undergoing subsequent reactions with small molecules, for instance to remove such small molecules from a solution.

A system and method for producing fluid for peritoneal dialysis (PD) is disclosed. The system comprises a fluid path including one or more PD-concentrate connectors each connected to one or more sources of PD-concentrate fluid, and a water connector connected to a source of water. The system further includes a forward osmosis FO-unit including a draw side and a feed side separated by a FO-membrane. The FO-unit is fluidly connected to the fluid path. The FO-unit receives the one or more PD-concentrate fluids at the draw side, and receives the water at the feed side. Purified water is transported to one or more PD-concentrate fluids through the FO-membrane by means of an osmotic pressure gradient between the draw side and the feed side. The transported purified water is further purified by the FO-membrane and the one or more PD-concentrate fluids is diluted to produce a diluted PD-concentrate fluid.

Systems, methods, and/or apparatuses may be operative to perform a dialysis process that includes a displacer infusion process. The dialysis machine may include at least one processor and a memory coupled to the at least one processor, the memory comprising instructions that, when executed by the processor, may cause the at least one processor to access dialysis information for a dialysis process performed by a dialysis machine, the dialysis information indicating a target substance to be displaced from a binding compound by a displacer, and determine an infusion profile for infusing the displacer into a patient during a displacer infusion process of the dialysis process, the infusion profile determined based on the dialysis information and an infusion constraint. Other embodiments are described.

A processor of a medical device configured to communicate with a remote server can be programmed to protect the medical device from exposure to unauthorized or malicious software. A system or method to implement this form of protection can include, for example, at least one processor on the medical device, a control software module that controls the operation of the medical device and is executable on the processor, a data management module that manages data flow to and from the control software module from sources external to the medical device, and an agent module that has access to a limited number of designated memory locations in the medical device. In addition, a hemodialysis apparatus can be configured to operate in conjunction with an apparatus for providing purified water from a source such as a municipal water supply or a well. A system for controlling delivery of purified water to the hemodialysis apparatus can comprise a therapy controller of the hemodialysis apparatus configured to communicate with a controller of a water purification device, and a user interface controller of the hemodialysis apparatus configured to communicate with the therapy controller, and to send data to and receive data from a user interface.

Provided herein are methods for maintaining physiological levels of nitrite in a subject undergoing hemodialysis. Also provided herein are methods of administering pharmaceutically acceptable sodium nitrite to a subject undergoing hemodialysis.

A method includes collecting used dialysis fluid in a container and combining the dialysis fluid with an acid to lower the pH value of the used dialysis fluid.

A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient to the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. In addition, the hemodialysis system includes two reservoirs which can be alternately placed in the dialysis flow path using various controllable fluid valves. The weight, and therefore the level of dialysate, of each reservoir is measured by a preferred level sensor having a lever arm, a load cell, and a tilt sensor. The load cell and tilt sensor are electrically connected to a processor for sending force and tilt measurements to the processor. The processor may analyze the tilt measurements to correct for any inaccurate measurements of the load cell caused by the tilt.

A system for blood treatment can include a dialysis machine and an ultrasonic authentication device connected to the blood treatment machine, the ultrasonic authentication device configured to scan a label and send signals containing label information to the dialysis machine.

Provided are methods and arrangements wherein gases are removed via semipermeable membranes from aqueous, optionally complex biological substance mixtures, by dialysis in an aqueous medium. Special carrier molecules for gases are included in the dialysate that are regenerated in the dialysate circuit so that they can be used for further gas exchange cycles on the membrane.

The invention relates to a device for removing a gas from an aqueous liquid, particularly a blood liquid, comprising a first compartment permeated by the aqueous liquid during operation of the device; a second compartment permeated by a purging gas during operation of the device, the first compartment and the second compartment being separated from each other by a semipermeable membrane; and a third compartment permeated by a liquid proton donor during operation of device, said proton donor being an organic or inorganic acid, the first compartment and the third compartment being separated from each other by a membrane permeable to ions, and the membrane permeable to ions comprising at least one cation conductor.