Systems, methods, and/or apparatuses may be operative to perform a dialysis process that includes a displacer infusion process. The dialysis machine may include at least one processor and a memory coupled to the at least one processor, the memory comprising instructions that, when executed by the processor, may cause the at least one processor to access dialysis information for a dialysis process performed by a dialysis machine, the dialysis information indicating a target substance to be displaced from a binding compound by a displacer, and determine an infusion profile for infusing the displacer into a patient during a displacer infusion process of the dialysis process, the infusion profile determined based on the dialysis information and an infusion constraint. Other embodiments are described.

A CRRT apparatus comprising a filtration unit (2), a blood circuit (17), a blood pump (21), a dialysate line (13) and one or more lines (8; 51; 57; 58; 63; 69; 67; 74) to transfer a respective solution into blood; a fluid source for each of said one or more lines, wherein said solution comprises at least one buffer agent in the form of bicarbonate or bicarbonate precursor. A control unit (12) is configured to receive a patient prescription and to determine a parameter (J.sub.buffer_load/BW) indicative of a steady state acid-base balance in the blood of the patient who has to undergo a CRRT blood treatment, wherein said parameter is determined as a function of the concentration of said buffer agent in said fluid source and as a function of the estimated or calculated patient systemic steady state concentration of bicarbonate and/or bicarbonate precursors.

Systems, methods, and/or apparatuses may be operative to perform a dialysis process that includes a displacer infusion process. The dialysis machine may include at least one processor and a memory coupled to the at least one processor, the memory comprising instructions that, when executed by the processor, may cause the at least one processor to access dialysis information for a dialysis process performed by a dialysis machine, the dialysis information indicating a target substance to be displaced from a binding compound by a displacer, and determine an infusion profile for infusing the displacer into a patient during a displacer infusion process of the dialysis process, the infusion profile determined based on the dialysis information and an infusion constraint. Other embodiments are described.

A dialysis fluid system includes a dialysis fluid inlet; a dialysis fluid outlet; a pump positioned and arranged to pump dialysis fluid through the dialysis fluid inlet and the dialysis fluid outlet; and an inductive heater located between the dialysis fluid inlet and the dialysis fluid outlet, the inductive heater including a fluid flowpath positioned and arranged to receive non-heated dialysis fluid from the dialysis fluid inlet and to output heated dialysis fluid to the a dialysis fluid outlet, a conductive heater element located within the fluid flowpath so as to be or act as a secondary coil of a transformer, and a primary coil of the transformer located outside of the fluid flowpath and positioned so as to magnetically induce a current into the conductive heater element, causing the conductive heater element and surrounding fluid to heat.

An apparatus for extracorporeal blood treatment comprising a filtration unit, a blood circuit comprising a blood with-line and a blood return line, and a fluid circuit. The fluid circuit comprises at least one or more water inlet ducts for receiving water, a dialysis preparation assembly comprising one or more concentrated sources housing a respective concentrate solution and configured to prepare a mixed solution of a dialysis fluid, wherein the water inlet duct is configured to provide water to the dialysis preparation assembly for preparing said mixed solution of dialysis fluid. The fluid circuit further comprises an infusion preparation assembly comprising one or more concentrated sources housing a respective concentrate solution and configured to prepare a mixed solution of an infusion fluid, wherein the water inlet duct is configured to provide water to the infusion preparation assembly for preparing said mixed solution of infusion fluid.

The invention relates to a blood line (108) comprising an infusion site (145) intended to inject into the line a solution, comprising: a first main channel (200) having a first passage section, a second main channel (220) having a second passage section, means for the formation (210) of a turbulence area located downstream from the first main channel, located upstream from the second main channel, these formation means comprising a first fluid passage means (224) defining a reduction (225) in the passage section and whose smallest passage section is smaller than the first passage section and smaller than the second fluid passage section, a secondary channel (230) comprising an inlet (231) for letting in the solution and an outlet (232) in fluid communication with the first main channel or the means for the formation of a turbulence area or the second main channel.

The present disclosure relates to a blood line (108) comprising an infusion site (145) intended to inject into the line a solution comprising: —a first main channel (200) having a first passage section, —a second main channel (220) having a second passage section, —means for the formation (210) of a turbulence area located downstream from the first main channel, located upstream from the second main channel, these formation means comprising a first fluid passage means (224) defining a reduction (225) in the passage section and whose smallest passage section is smaller than the first passage section and smaller than the second fluid passage section, —a secondary channel (230) comprising an inlet (231) for letting in the solution and an outlet (232) in fluid communication with the first main channel or the means for the formation of a turbulence area or the second main channel.

The specification discloses a portable dialysis machine having a detachable controller unit and base unit with an improved reservoir heating system. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a reservoir with an internal pan and external pan, separated by a space that holds a heating element. The heating element is electrically coupled to electrical contacts attached to the external surface of the external pan.

A method of preparing a solution for use during a dialysis, hemodialysis, or Continuous Renal Replacement Therapy (CRRT) treatment of a patient is provided. An antibiotic or other drug is added (48, 50, 52) to a solution and the concentration or dosing of the antibiotic or other drug within the solution is adjusted (72) as required based on a determination (64) of serum level of the antibiotic in a blood sample of a patient.

There is provided a blood purification apparatus with which the efficiency of dialysate purification can be improved and the reduction in the amount of electrolytes contained in dialysate and necessary for treatment can be suppressed. The blood purification apparatus includes a storage device capable of storing a predetermined amount of dialysate that is necessary for blood purification treatment, a dialysate circulation line through which the dialysate is allowed to circulate by introducing the dialysate in the storage device into the dialyzer and draining waste liquid from the dialyzer into the storage device, and the dialysate purification device that purifies the dialysate in the dialysate circulation line. A treatment state in which the dialysate is allowed to be introduced into the dialyzer without flowing through the dialysate purification device and a purification state in which the dialysate is allowed to be purified by the dialysate purification device are taken switchably.