A blood treatment machine includes a patient comfort feedback mechanism configured to be adjusted by a patient to indicate comfort levels of the patient. The machine is configured to adjust one or more treatment parameters based on the patient feedback.

Microbubbles detached from a blood circuit and a blood purification unit are discharged with the use of a backflow generated at the instant that a roller of a blood pump releases a squeezable tube. In a normal rotation step, a region filled with a priming solution after a priming step is closed by a closing unit, and a rotor of a blood pump is rotated normally until a roller of the blood pump releases a squeezable tube to generate a backflow. After the backflow is generated at the release of the squeezable tube by the roller of the blood pump, bubbles are moved by reversely rotating the rotor while disabling the closing by the closing unit. Thus, the bubbles are discharged through a discharge unit.

Methods and systems for controlling one or more pumps of a heart-lung-machine. An illustrative method may comprise receiving an actual flow rate of a pump, determining the actual flow rate is from a primary pump, determining an available amount of the actual flow rate of the primary pump that is available to one or more subordinate pumps, comparing the available amount of the actual flow rate of the primary pump to a sum of set flow rates of the one or more subordinate pumps, and operating the one or more subordinate pumps in a proactive control mode or a reactive control mode.

A heart lung machine (HLM) includes: a pump actuator; an actuator control unit (ACU) operably connected to the pump actuator; a processing unit configured to receive a set of parameter data from the actuator; a display device configured to present a subset of the set of parameter data; and an input control device operably connected to the pump actuator. The input control device includes a rotatable knob. The ACU may be configured to: determine that the pump actuator has been stopped in response to a pump-stop trigger event; determine that the rotatable knob has been rotated to a first position; and in response to determining that the rotatable knob has been rotated to the first position, starting the pump actuator.

A perfusion system includes a fluid reservoir configured to hold a portion of fluid, the portion of fluid having a volume, the fluid reservoir having a total capacity that is greater than the volume; an imaging device, the imaging device configured to obtain image data corresponding to the fluid reservoir; and a controller. The controller is configured to receive the image data from the imaging device; determine the volume based on the image data; and facilitate control, in response to at least one of a user input and the determined volume of the portion of fluid, of an operating parameter corresponding to the fluid reservoir to facilitate changing or maintaining the volume of the portion of the fluid.

The present disclosure relates to a control device or closed-loop control device programmed to control or regulate a blood treatment apparatus during an administered treatment of a patient's blood using an extracorporeal blood tubing set and the blood treatment apparatus based on set adjustable values of treatment parameters set by using the blood treatment apparatus or using another device optionally connected to the extracorporeal blood tubing set, wherein the control device or closed-loop control device is further programmed, after reading, to compare at least one measurement value collected during the administered treatment, as the actual value of a blood parameter with a stored target value of the blood parameter. Based on this comparison and observation of a set adjustable value of one of the treatment parameters, either a correction value or correction factor to change the set adjustable value or a new adjustable value is determined in each case.

This document describes medical systems for monitoring parameters of a patient during a medical procedure. A user, such as a practitioner, can provide input of parameter settings for ranges of patient parameters and semi-autonomous adjustments to the parameters. The semi-autonomous adjustments can be executed at a later time during the procedure, based on sensed real-time changes to the patient parameters. A computer system can monitor, in real-time, the patient parameters and generate GUI displays to be presented at the user's device. The GUI displays can output sensed real-time changes in the patient parameters, controls to adjust ranges for each of the parameters, and controls to perform semi-autonomous adjustments. The computer system can also generate projected trends for the real-time parameters, which can be used by the user to adjust patient parameters during the procedure. User selection of semi-autonomous adjustments can be executed by the computer system at a heart/lung machine.

An extracorporeal photopheresis system includes a separator with a disposable fluid circuit including a treatment container, an irradiation device configured to treat the contents of the treatment container, and a controller configured to control the system to perform a procedure including drawing anticoagulated whole blood into the fluid circuit from a blood source and returning to the blood source a treated target cell component, a portion of a red blood cell component remaining in the fluid circuit, and/or a portion of a plasma component remaining in the fluid circuit. The controller is further configured to estimate an end-of-procedure fluid balance estimated based on manual or automatic inputs including a patient body weight associated with the blood source and a total blood volume of the blood source, indicate the fluid balance to an operator, and receive one or more changes that affect the fluid balance after indicating the fluid balance.

A method of dialysis is provided that includes sensing the concentration of potassium in a patient's blood serum, in used dialysate resulting from treating the patient, or in both. The method involves generating a sensed value of the concentration of potassium, comparing the sensed value with one or more values stored in a memory, and generating a control signal based on the comparison. Supplemental potassium solution is infused into the treatment dialysate, based on the control signal. The comparison can be made to patient-historical data, population data, or both.

Extracorporeal blood treatment systems and methods to display graphical user interfaces displaying a plurality of fluids areas, each including a flow rate, and displaying adjustment notifications proximate one or more fluid areas. For example, when a user adjusts a flow rate to a limit, one or more notifications may be displayed proximate other flow rates that may be adjusted to modify the limit.