A flow path cassette includes superimposed first and second flexible sheets, where a plurality of flow paths are disposed therebetween and detection channel portions are disposed at one or more points along one or more of the plurality the flow paths. Each of the detection channel portions includes a first bulging portion and an opposing second bulging portion. A plate member is aligned with the second bulging portion, and a deformation preventative member is aligned with the first bulging portion. The plate member may move with the second bulging portion, while the deformation preventative member prevents deformation of the first bulging portion.

A fluid diverting device for an apparatus for extracorporeal treatment of blood is configured to be placed in-line between a main portion (22) of the apparatus (1) and a vascular access of a patient (P) and comprises: a substantially H-shaped conduits assembly comprising a withdrawal conduit (23), a return conduit (24) and at least one bridging conduit (25, 125) connecting the withdrawal conduit (23) to the return conduit (24). The withdrawal conduit (23) is connectable upstream and downstream to a withdrawal line (6) of the apparatus (1), the return conduit (24) is connectable upstream and downstream to a return line (7) of the apparatus (1). A plurality of valves (26, 27, 28, 29, 30, 32) or distributors (201, 202) operate on the withdrawal conduit (23), on the return conduit (24) and on the at least one bridging conduit (25) and are configured to divert a flow of liquid and/or blood without disconnecting the patient (P).

The present invention relates to a method for disconnecting two fluid-conducting line sections of a medical device which are detachably interconnected, wherein a first line section of the two line sections has at least partially an elastic property. The method comprises the steps of enclosing a fluid volume in the two line sections, generating a reduced pressure in the two line sections, as a result of which elastic deformation from a starting position into a tensioned position takes place in and/or on the first line section, wherein a fluid volume contained in the first line section is lower in the tensioned position than a fluid volume contained in the starting position, and detaching the connection of the line sections, wherein the fluid volume contained in the first line section in the tensioned position increases. Furthermore, the invention relates to a medical device which is configured to carry out a method of this kind.

Described are embodiments that include methods and devices for separating composite liquids into components. Embodiments involve the use of a flexible membrane for separating a composite liquid into components. The composite liquid may include, in embodiments, a cellular containing liquid, such as whole blood or components of whole blood. In one specific embodiment, the composite liquid is a buffy coat.

A hemodiafiltration system with a disposable pumping unit is disclosed. An example system includes a medical fluid pump actuator, a medical fluid heater, a blood filter and a disposable unit. The example disposable unit includes a medical fluid cassette portion including a medical fluid cassette housing configured to be operatively connected to the medical fluid pump actuator to pump medical fluid through the medical fluid cassette portion when the medical fluid cassette portion is in fluid communication with a medical fluid source. The example medical fluid cassette portion is also configured to be placed in fluid communication with the blood filter and with an extracorporeal circuit communicating with the blood filter, the fluid communication enabling hemodiafiltration to be performed. The example disposable unit also includes a heater bag configured to be placed in operable communication with the medical fluid heater and in fluid communication with the medical fluid cassette portion.

A biological component cassette includes a cassette main body having a flow path for the liquid in an interior of the cassette main body. The cassette main body is flexible and has a sheet-like shape. The biological component cassette includes a frame that is less flexible than the cassette main body. The frame includes an accommodation chamber in which the cassette main body is accommodated. A side portion of the frame forms at least part of the accommodation chamber. When the cassette main body is accommodated in the accommodation chamber, one surface of the cassette main body is covered by a bottom portion of the accommodation chamber, and another surface of the cassette main body is exposed to an external environment.

A hemodiafiltration system with a disposable pumping unit is disclosed. An example system includes a medical fluid pump actuator, a medical fluid heater, a blood filter and a disposable unit. The example disposable unit includes a medical fluid cassette portion including a medical fluid cassette housing configured to be operatively connected to the medical fluid pump actuator to pump medical fluid through the medical fluid cassette portion when the medical fluid cassette portion is in fluid communication with a medical fluid source. The example medical fluid cassette portion is also configured to be placed in fluid communication with the blood filter and with an extracorporeal circuit communicating with the blood filter, the fluid communication enabling hemodiafiltration to be performed. The example disposable unit also includes a heater bag configured to be placed in operable communication with the medical fluid heater and in fluid communication with the medical fluid cassette portion.

The present disclosure relates to a calculation device for determining an interdialytic sodium intake of a patient and/or for determining a non-osmotically triggered interdialytic liquid intake, including a storage device and/or an input device configured for storing or for entering parameter values of the patient; a computing device, configured for calculating the interdialytic sodium intake of the patient and/or for calculating his non-osmotically triggered interdialytic liquid intake; and an output device for outputting a signal for controlling or closed-loop controlling a communication device and/or a medical blood treatment apparatus.

Provided is a blood component sampling cassette which can be efficiently manufactured at low cost compared to a conventional cassette, a method for manufacturing the blood component sampling cassette, a blood sampling circuit set and a blood component sampling system. The blood component sampling cassette includes a cassette main body having a plurality of flow paths including an introduction line, a blood component transfer line and a retransfusion line. The cassette main body includes a first sheet and a second sheet which are formed of a soft material compatible with autoclave sterilization. The first sheet and the second sheet are overlaid in a thickness direction and bonded to each other. A plurality of flow paths is formed between the first sheet and the second sheet.

A blood bag system includes a BC pooling bag for centrifugation of a buffy coat, a filter for removing white blood cells from a supernatant liquid transferred from the BC pooling bag, a platelet preserving bag for reserving the supernatant liquid that has passed through the filter, a first tube connecting the BC pooling bag and an inlet of the filter, a second tube connecting the platelet preserving bag and an outlet of the filter, and a cassette to be fixed in the centrifugation and separation apparatus. The first tube and the second tube are disposed within the cassette. The cassette includes a first clamp section for closing and opening the first tube, and a second clamp section for closing and opening the second tube.