A flow path cassette includes superimposed first and second flexible sheets, where a plurality of flow paths are disposed therebetween and detection channel portions are disposed at one or more points along one or more of the plurality the flow paths. Each of the detection channel portions includes a first bulging portion and an opposing second bulging portion. A plate member is aligned with the second bulging portion, and a deformation preventative member is aligned with the first bulging portion. The plate member may move with the second bulging portion, while the deformation preventative member prevents deformation of the first bulging portion.

A system for regulating blood flow in extracorporeal circulation, and including a blood reservoir to receive blood from a patient, an oxygenator to condition the blood, a centrifugal pump to pump the blood from the blood reservoir to the oxygenator and back to the patient, an electronic remote clamp to regulate flow of the blood, and a controller to operate in a flow control mode and a speed control mode. The controller includes an operational element to set a blood flow value in the flow control mode and to set a speed of the centrifugal pump in the speed control mode. The controller to automatically switch between the flow control mode and the speed control mode in response to one or more trigger conditions and to automatically switch between the speed control mode and the flow control mode in response to opening the electronic remote clamp.

A blood pressure prediction method and an electronic device using the same are provided. The method includes the following steps. A training data set is collected. A first blood pressure prediction model is established according to the training data set. Hemodialysis parameter data of a target patient is received, wherein the hemodialysis parameter data includes a first hemodialysis parameter at a previous time point and a second hemodialysis parameter at a current time point. A hemodialysis parameter variation amount between the first hemodialysis parameter and the second hemodialysis parameter is calculated. The hemodialysis parameter variation amount is provided to the first blood pressure prediction model to generate a prediction blood pressure variation associated with a next time point. An operation is performed according to the prediction blood pressure variation of the target patient.

The invention relates to a blood treatment device for carrying out an extracorporeal blood treatment in which blood is guided in a blood guidance device having a main blood line and at least one secondary line, the latter being fluidically connected to the main blood line and the main blood line having a dialyzer and, downstream from the dialyzer, a blood treatment element, wherein the blood treatment device has a control device; and a pump configuration, which is equipped for generating blood flows in the main blood line and also in the at least one secondary line, wherein the control device is designed to operate the pump configuration in such a way that a first blood flow rate in the dialyzer is decoupled from a second blood flow rate in the blood treatment element. Furthermore, the invention relates to a blood guidance device for cooperation with the blood treatment device as well as for a blood treatment system.

Provided is an extracorporeal circulator capable of judging a timing suitable for detachment with high accuracy. The extracorporeal circulator includes a blood removal side catheter with a part that can be inserted into a patient and guide the blood taken from the patient; a pump that can take the blood from the patient and return the blood to the patient; a blood transfer side catheter provided downstream of the pump, and that has a part that can be inserted into the patient and guide the blood sent out from the pump back into the patient; a pump rotation speed detection unit that can detect a rotation speed of the pump; and a control system including at least one of an extracorporeal circulation management system that can judge stability of the extracorporeal circulation and a cardiac function measurement system that can judge stability of a heart function of the patient.

A pressure measurement pod for use in blood circuits includes a pressure sensing pod defining a chamber and having a rigid wall portion and an integral flexible wall portion forming a flexible, moveable, fluid-impermeable diaphragm with a first major side thereof facing an interior of the chamber and a second major side opposite the first major side. The second major side faces outwardly away from the chamber, and the pod has ports on sides of the chamber. The internal surfaces of the chamber and ports are shaped such that any contour following the internal surfaces to the outside of one of the ports traces only surfaces characterized by positive or neutral draft angles such that invasive mold portions may be withdrawn through the ports thereby permitting the pressure measurement pod to be molded in a single shot molding process.

Equipment for the control of biomedical devices during extracorporeal circulation. The equipment includes at least one basic structure and a (e.g., tangible) controller or a control unit/device/component/etc. that is assembled on the basic structure and provided with at least one control unit/etc. operationally connectable to at least one biomedical device for extracorporeal circulation and configured to control it. The controller/etc. comprise at least one emergency control unit, operationally connectable to the biomedical device and configured to control the latter following a malfunction of the control unit.

The invention relates to a medical device comprising a printable electrical component (1), the printable electrical component (1) comprising a plastic substrate (L1) wherein at least electrical component (E) is applied to the plastic substrate, wherein the electrical component (E) comprises a dried conductive ink, wherein the plastic substrate is selected from the group comprising polycarbonate, cycloolefin copolymers, polymethylacrylate, polypropylene and wherein the dried conductive ink comprise silver and/or gold, wherein the electrical component (E) comprises feather-like and/or meander-like and/or spiral-shaped sections, whereby the medical device further comprises a fluid line, wherein the printable electrical component is located on the outside of the fluid line. The invention also relates to a medical device comprising a printable electrical component (1) the printable electrical component (1) comprising a plastic substrate (L1), wherein at least one electrical component (E) is applied to the plastic substrate, wherein the electrical component (E) comprises a dried conductive ink, wherein the plastic substrate is selected from a group comprising polycarbonate, cycloolefin copolymers, polymethyl-methacrylate, polypropylene and wherein the dried, conductive ink comprises silver and/or gold, wherein the electrical component (E) comprises at least one conductor section or at least two electrodes, characterized in that the electrical component (E) is part of an expansion sensor and/or a pressure sensor and/or a thermal flow sensor.

A dialysis treatment system for hemodialysis includes a processor to acquire blood flow information and patient biological information in a blood circuit for hemodialysis, the patient biological information being peripheral vascular resistance information, blood pressure information, face information, body movement information, temperature information, and humidity information and to acquire patient individual difference information from the blood related information; and to perform dialysis treatment for the patients on the basis of the patient individual difference information.

A method controls a device for extracorporeal blood gas exchange. The device has a membrane as a gas-liquid barrier between a bloodstream and a gas stream. The membrane further makes possible a passing over of the carbon dioxide content from the bloodstream into the gas stream. The device has at least one actuator. A change in a value of an operating parameter of the actuator brings about a change in a value of the carbon dioxide content that passes over from the bloodstream into the gas stream. The method further includes providing breathing gas information that indicates a carbon dioxide concentration in breathing gas and providing a control signal, which indicates a request for setting a value of the operating parameter and changing of the value of the operating parameter as a function of the carbon dioxide concentration in the breathing gas.