Temperature control device for use in fluid-based hyper/hypothermia systems, comprising a connection unit for connecting the device to a local power network, and a fluid temperature control unit for heating or cooling a fluid. The device includes a power supply unit, by which electrical consuming components of the fluid temperature control unit are supplied with power, and which effects supply of the electrical consuming components with direct current.

The described invention is a hyperthermia and hyperoxygenation medical apparatus for treating diseases of the blood and purification of stored blood supplies. The invention comprises a hollow chamber through which blood is made to flow. Within the hollow chamber are a heating element and a gas diffuser. As blood flows through the chamber, blood is heated to a preset limit while ozone or other beneficial gas is diffused into the blood by a diffuser with pores to a preset concentration. After heating and gasification, blood exits the hollow chamber and is either returned to the patient or returned to storage. The hollow chamber, heating element and gas diffuser are designed to maintain efficient, linear blood flow through the invention, in part by taking advantage of die radial symmetry of the hollow chamber and diffuser designs. Linear flow ensures uniform and controlled heating and gasification of the blood with negligible undesirable turbulence to the blood components.

A catheter includes a tubular body to be inserted into a living body. The tubular body has a lumen that is held in fluid communication with an injection port defined in a distal end of the tubular body and a suction port near a proximal end of the tubular body, and the suction port is closed when the injection port is open, and the injection port is closed when the suction port is open.

A system including tubing and a filter configured to be fluidly coupled to a vacuum source and to a heater/cooler unit by the tubing. The filter includes a filter container having negative air pressure in the filter container provided by the vacuum source to pull aerosol from the heater/cooler unit into the filter container and eliminate and/or reduce the aerosol emitted from the heater/cooler unit.

An extracorporeal blood treatment apparatus comprises: a blood treatment device (2); an extracorporeal blood circuit comprising a blood withdrawal line (6) and a blood return line (7) coupled to the extracorporeal blood treatment device (2), wherein the blood return line (7) presents a heating zone (14) coupled or configured to be coupled to a blood warmer (15); a blood pump (6) configured to be coupled to a pump section of the blood withdrawal line (6); at least a post-infusion line (13, 13′) connected to the blood return line (7) upstream of the heating zone (14); an air trapping device (9) placed on the blood return line (7) upstream of the heating zone (14).

A system for reducing toxicity from intravascular triggered drug delivery includes a chamber comprising an inflow port, an outflow port, and a filter positioned upstream of the outflow port. A trigger module is configured to trigger the release of a drug from an intravascular triggered drug delivery system present in blood in the chamber. A method for reducing toxicity from intravascular triggered drug delivery includes the steps of removing blood comprising an intravascular triggered drug delivery system from a patient's vascular system and delivering the blood to a chamber, applying a trigger to the blood to release a drug from the intravascular triggered drug delivery system, filtering the drug from the blood, and returning the filtered blood to the patient.

The present invention generally relates to a process suitable for extracorporeal lung support. The process comprises contacting blood with a dialysis liquid separated by a semipermeable membrane. Oxygen is introduced into blood and/or into the dialysis liquid prior to contacting blood and dialysis liquid being separated by the semipermeable membrane. The process is versatile and allows for blood oxygenation as well as removal of at least one undesired substance occurring in the blood, selected from carbon dioxide, bicarbonate and hydrogen cations, from blood. Thereby, the present invention takes advantage of the Haldane effect in the extracorporeal contacting step. The undesired substance can be efficiently transported across a semipermeable membrane to the dialysis liquid. In contrast to extracorporeal carbon dioxide removal methods of the prior art (ECCCbR), the present invention employs a versatile dialysis liquid that allows to adjust the pH and buffering capacity of the dialysis liquid, to add fluids to the dialysis liquid and/or to the blood and to remove substances from the blood in the extracorporeal circuit, depending on the conditions and needs. The present invention also provides regeneration and recycling of the dialysis liquid, and thus for its repeated use. The present invention is suitable for treating human or animal subjects suffering from lung failure or lung disorders.

A pump cassette is disclosed. The pump cassette includes a housing having at least one fluid inlet line and at least one fluid outlet line. The cassette also includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps a fluid from the fluid inlet line to the fluid outlet line. A hollow spike is also included on the housing as well as at least one metering pump. The metering pump is fluidly connected to the hollow spike on the housing and to a metering pump fluid line. The metering pump fluid line is fluidly connected to the fluid outlet line.

A renal replacement apparatus (100), having a hemofilter (108); an extracorporeal blood circuit (102) configured to communicate blood from a patient (104), through the hemofilter, and back to the patient; and a flow measuring device (150) configured to measure at least one blood flow property as the blood is leaving the hemofilter and before the blood returns to the patient at a flow measuring device location (152), wherein the flow measuring device comprises at least one of a viscometer and a rheometer. Alternately, or in addition, the renal replacement apparatus may include thermomodulator system (222) including at least one thermomodulator configured to selectively heat and cool the blood in the extracorporeal blood circuit. The renal replacement apparatus (100) may have a controller (160). The controller may use artificial intelligence. Other embodiments are described herein.

A multi-stage system for warming blood that enables safe and rapid blood transfusions in the field. The first stage of the system is a rapid blood warming device that heats blood quickly from cold storage to body temperature. This stage may use a high-energy power source, such as AC power, that is available in a facility such as a hospital. The second stage is a portable heated blood transport device into which heated blood bags are placed for transportation to a patient. This device keeps the blood bags warm using battery power. Because blood bags are pre-heated with the rapid warming device, the transport device can be lightweight and portable. An optional third stage is a transfusion temperature regulating device that boosts the final temperature of blood just before it enters the patient. All three devices may have sensors and controllers that maintain blood temperature within desired ranges.